확산텐서영상 팬텀 제작을 위한 식물섬유 재료의 특성에 관한 연구
A Study on the Characteristics of Plant Fiber Materials for Diffusion Tensor Imaging Phantom
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The purpose of this study was to reconstruct diffusion tensor tractography (DTT) using stem of garlic and asparagus for in vitro phantom of diffusion tensor imaging (DTI), and to compare and evaluate the fractional anisotropy (FA) value and the apparent diffusion coefficient (ADC) value to determine whether it can be used as materials for in vitro phantoms. Among various plant fibers such as stem of garlic, palmae, cotton, asparagus, etc., stem of garlic and asparagus, which are considered to be the most suitable for making phantoms, and whose shape is considered to be the most suitable for making phantoms, were selected and tests were conducted. Holes were made in a plastic bucket at an angle of 0°, 30°, 60°, 90°, and 120°, then tubes were inserted. In the tube, asparagus and stem of garlic were inserted as far in as possible, and the inserted tube was inserted into the center of the heat bathed gelatin to harden. We were able to reproduce DTT images in asparagus and stem of garlic. Fiber tissues of asparagus and stem of garlic did not show complete connectivity, but the reconstructed images of DTT showed good connectivity. The FA values of asparagus in the tubes were 0.198 at 0° (straight), 0.207 at 30°, 0.187 at 60°, 0.231 at 90°, and 0.204 at 120°. In addition, the FA values of stem of garlic in the tubes were 0.235 at 0°, 0.236 at 30°, 0.216 at 60°, 0.218 at 90°, and 0.257 at 120°. The ADC values of asparagus in the tubes were 1.545 at 0°, 1.677 at 30°, 1.629 at 60°, 1.535 at 90°, and 1.725 at 120°. In addition, the ADC values of stem of garlic in the tubes were 1.252 at 0°, 1.396 at 30°, 1.698 at 60°, 1.756 at 90°, and 1.466 at 120°. For the best expressed DTT reconstruction image, it showed the longest connectivity in the straight line as we hypothesized. In addition, when comparing the FA values and ADC values of fiber tissues of stem of garlic and asparagus, FA value was generally higher in stem of garlic and ADC value was slightly higher in asparagus.
Abstract
The purpose of this study was to reconstruct diffusion tensor tractography (DTT) using stem of garlic and asparagus for in vitro phantom of diffusion tensor imaging (DTI), and to compare and evaluate the fractional anisotropy (FA) value and the apparent diffusion coefficient (ADC) value to determine whether it can be used as materials for in vitro phantoms. Among various plant fibers such as stem of garlic, palmae, cotton, asparagus, etc., stem of garlic and asparagus, which are considered to be the most suitable for making phantoms, and whose shape is considered to be the most suitable for making phantoms, were selected and tests were conducted. Holes were made in a plastic bucket at an angle of 0°, 30°, 60°, 90°, and 120°, then tubes were inserted. In the tube, asparagus and stem of garlic were inserted as far in as possible, and the inserted tube was inserted into the center of the heat bathed gelatin to harden. We were able to reproduce DTT images in asparagus and stem of garlic. Fiber tissues of asparagus and stem of garlic did not show complete connectivity, but the reconstructed images of DTT showed good connectivity. The FA values of asparagus in the tubes were 0.198 at 0° (straight), 0.207 at 30°, 0.187 at 60°, 0.231 at 90°, and 0.204 at 120°. In addition, the FA values of stem of garlic in the tubes were 0.235 at 0°, 0.236 at 30°, 0.216 at 60°, 0.218 at 90°, and 0.257 at 120°. The ADC values of asparagus in the tubes were 1.545 at 0°, 1.677 at 30°, 1.629 at 60°, 1.535 at 90°, and 1.725 at 120°. In addition, the ADC values of stem of garlic in the tubes were 1.252 at 0°, 1.396 at 30°, 1.698 at 60°, 1.756 at 90°, and 1.466 at 120°. For the best expressed DTT reconstruction image, it showed the longest connectivity in the straight line as we hypothesized. In addition, when comparing the FA values and ADC values of fiber tissues of stem of garlic and asparagus, FA value was generally higher in stem of garlic and ADC value was slightly higher in asparagus.
참고문헌 (21)
- 이정훈, "디지털 감산 혈관조영술과 자기 공명 혈관조영술에서 중대뇌동맥의 협착 측정을 위한 North American Symptomatic Carotid Endarterectomy Trial 및 Warfarin-Aspirin Symptomatic Intracranial Disease 방법의 비교 평가", 방사선기술과학, 42(5), pp.351~356 (2019), 대한방사선과학회[DOI]
- 이정훈, "인공 무릎관절에서 자화율 인공물의 감소를 위한 O-MAR XD 기법의 평가", 방사선기술과학, 41(5), pp.413~419 (2018), 대한방사선과학회[DOI]
- Pierpaoli C, "Toward a quantitative assessment of diffusion anisotropy", Magnetic Resonance in Medicine, 36(6), pp.893~906 (1996)
- Basser PJ, "Diffusion-tensor MRI : Theory, experimental design and data analysis–a technical review", NMR in Biomedicine: An International Journal Devoted to the Development and Application of Magnetic Resonance In Vivo, 15(78), pp.456~467 (2002)
- Werring DJ, "Diffusion tensor imaging of lesions and normal-appearing white matter in multiple sclerosis", Neurology, 52(8), pp.1626~ (1999)
- Assaf Y, "Diffusion tensor imaging(DTI)-based white matter mapping in brain research : A review", Journal of Molecular Neuroscience, 34(1), pp.51~61 (2008)
- Lichenstein SD, "Diffusion capillary phantom vs. human data: Outcomes for reconstruction methods depend on evaluation medium", Frontiers in Neuroscience, 10, pp.407~ (2016)
- Watanabe M, "Flexible ex vivo phantoms for validation of diffusion tensor tractography on a clinical scanner", Radiation Medicine, 24(9), pp.605~609 (2006)
- Ni H, "Effects of number of diffusion gradient directions on derived diffusion tensor imaging indices in human brain", American Journal of Neuroradiology, 27(8), pp.1776~1781 (2006)
- 김상준, "Effects of MR Parameter Changes on the Quantification of Diffusion Anisotropy and Apparent Diffusion Coefficient in Diffusion Tensor Imaging: Evaluation Using a Diffusional Anisotropic Phantom", Korean Journal of Radiology, 16(2), pp.297~303 (2015), 대한영상의학회[DOI]
- Reischauer C, "Construction of a temperature-controlled diffusion phantom for quality control of diffusion measurements", Journal of Magnetic Resonance Imaging: An Official Journal of the International Society for Magnetic Resonance in Medicine, 29(3), pp.692~698 (2009)
- 박명환, "자기공명 확산텐서영상용 팬텀에 관한 연구 : 다방향 확산영상을 위한 구조개발", 석사, 의료영상공학전공, pp.2012
- Lorenz R, "Anisotropic phantoms for quantitative diffusion tensor imaging and fiber-tracking validation", Applied Magnetic Resonance, 33(4), pp.419~ (2008)
- Perrin M, "Validation of q-ball imaging with a diffusion fibre-crossing phantom on a clinical scanner", Philosophical Transactions of the Royal Society B : Biological Sciences, 360(1457), pp.881~891 (2005)
- Reischauer C, "Construction of a temperature-controlled diffusion phantom for quality control of diffusion measurements", Journal of Magnetic Resonance Imaging: An Official Journal of the International Society for Magnetic Resonance in Medicine, 29(3), pp.692~698 (2009)
- Madi S, "Diffusion tensor imaging of in vivo and excised rat spinal cord at 7 T with an icosahedral encoding scheme", Magnetic Resonance in Medicine: An Official Journal of the International Society for Magnetic Resonance in Medicine, 53(1), pp.118~125 (2005)
- Parker GJ, "Initial demonstration of in vivo tracing of axonal projections in the macaque brain and comparison with the human brain using diffusion tensor imaging and fast marching tractography", Neuroimage, 15(4), pp.797~809 (2002)
- Pfefferbaum A, "Postmortem MR imaging of formalin-fixed human brain", Neuroimage, 21(4), pp.1585~1595 (2004)
- Kunimatsu A, "Three-dimensional white matter tractography by diffusion tensor imaging in ischaemic stroke involving the corticospinal tract", Neuroradiology, 45(8), pp.532~535 (2003)
- Yamada K, "Tractography for arteriovenous malformations near the sensorimotor cortices", American Journal of Neuroradiology, 26(3), pp.598~602 (2005)
- Aoki S, "Quantitative evaluation of the pyramidal tract segmented by diffusion tensor tractography : Feasibility study in patients with amyotrophic lateral sclerosis", Radiation Medicine, 23(3), pp.195~199 (2005)
