저농도 유기용제 노출 사업장 근로자의 심혈관질환 위험인자 변화 추적(2008~2012)
Five Year’s Follow-up of the Cardiovascular Disease Risk Factors among the Low Level Organic Solvent Exposure Workers
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초록
Purpose: The objective of the present study was to evaluate the effects of occupational exposure to low dose organic solvents on the prevalence of cardiovascular risk factors. Methods: Study design was retrospective cohort study subjected on 191 exposures and 118 controls working in a petrochemical manufacture company. The eight indicators related to CVD risk were followed up for five years from 2008 to 2012. The risk level was compared during the follow up years and subject’s characteristics, and the change of risk level were analyzed with repeated measures ANOVA and multiple logistic regression analysis. Results: At the start year 2008, the rate over cutoff value (ROCV) of BS (p<.001) and mean systolic BP (p=.017) were higher in organic solvent exposure group and the others showed no difference. And by the subject’s characteristics, odds ratio of the ROCV of BS were higher in organic solvent exposure group and work shift group as 2.51 and 3.07. Comparing the results in 2012 to those of 2008, cardiovascular disease risk in organic solvent exposure group was about 1.5 times higher than that of in the control group. Conclusion: Gradual increase in the CVD risk was identified in organic solvent exposure group. However, the risk might be influenced by shift work and bad behaviors rather than organic solvent exposure.
Abstract
Purpose: The objective of the present study was to evaluate the effects of occupational exposure to low dose organic solvents on the prevalence of cardiovascular risk factors. Methods: Study design was retrospective cohort study subjected on 191 exposures and 118 controls working in a petrochemical manufacture company. The eight indicators related to CVD risk were followed up for five years from 2008 to 2012. The risk level was compared during the follow up years and subject’s characteristics, and the change of risk level were analyzed with repeated measures ANOVA and multiple logistic regression analysis. Results: At the start year 2008, the rate over cutoff value (ROCV) of BS (p<.001) and mean systolic BP (p=.017) were higher in organic solvent exposure group and the others showed no difference. And by the subject’s characteristics, odds ratio of the ROCV of BS were higher in organic solvent exposure group and work shift group as 2.51 and 3.07. Comparing the results in 2012 to those of 2008, cardiovascular disease risk in organic solvent exposure group was about 1.5 times higher than that of in the control group. Conclusion: Gradual increase in the CVD risk was identified in organic solvent exposure group. However, the risk might be influenced by shift work and bad behaviors rather than organic solvent exposure.
참고문헌 (23)
- 안희정, "제2형 당뇨병환자에서 식사의 규칙성을 중심으로 한 식습관 실태 분석", Diabetes and Metabolism Journal, 32(1), pp.68~76 (2008), 대한당뇨병학회
- Boden, G., "Fatty acids and insulin resistance", Diabetes Care, 19, pp.394~395 (1996)
- Chen, J. D., "Effects of occupational and nonoccupational factors on liver function tests in workers exposed to solvent mixtures", Archives of Environmental Health, 52, pp.270~274 (1997)
- 최은숙, "일개 전자 제조업체 남자 근로자의 대사증후군과 관련요인", Annals of Occupational and Environmental Medicine, 18(1), pp.35~45 (2006), 대한직업환경의학회
- Goetzel, R. Z., "Long-term impact of Johnson & Johnson's Health & Wellness Program on health care utilization and expenditures", Journal Occupational Environmental Medicine, 44(1), pp.21~29 (2002)
- Goh, V, H., "Effects of chronic exposure to low doses of trichloroethylene on steroid hormone and insulin levels in normal men", Environmental Health Perspectives, 106, pp.41~44 (1998)
- Goldstein, L. B., "Guidelines for the primary prevention of stroke a guideline for healthcare professionals from the American Heart Association", American Stroke Association, 2011, pp.42(2), 517~584
- Heo, K. H., "Effects of styrene exposure on the metabolic syndrome", 석사, pp.2008
- 허경화, "유해화학물질 노출 근로자의 대사증후군 발생위험에 대한 epinephrine과 norepinephrine의 영향", 한국직업건강간호학회지, 19(1), pp.88~96 (2010), 한국직업건강간호학회
- 허경화, "만성적인 스티렌 노출 근로자에 있어 대사증후군 유발에 관여하는 위험요인의 생리적 수준 변화", 한국산업보건학회지, 19(1), pp.30~38 (2009), 한국산업보건학회
- Kaukiainen, A., "Results of common laboratory tests in solvent-exposed workers", International Archives of Occupational Environmental & Health, 77, pp.39~46 (2004)
- Kim, H. J., "Health lifestyle behaviors associated with metabolic syndrome in a rural community", 석사, pp.2007
- "Statistics of occupational injuries and disease" (2011)[URL]
- "Korea National Health and Nutrition Examination Survey" (2011)[URL]
- "Cause of death statistics" (2014)[URL]
- "Occupational accidents and diseases statistics" (2012)[URL]
- "Risk assessment for the prevention of cardio-cerebrovascular disease at workplace"[URL]
- Kotseva, K., "Study of the cardiovascular effects of occupational exposure to organic solvents", International Archives of Occupational and Environmental Health, 71, pp.S87~S91 (1998)
- Kristensen, T. S., "Encyclopedia of environmental control technology" (1994), Gulf Publishing
- Lee, B. H., "The relations hip between body mass index and subjective health status perception in Korean women", 석사, pp.2000
- Mun, J. H., "The risk factors of metabolic syndrome and its relation with γ-GTP in steelmill workers", Diabetes Research Clinical Practice, 19(1), pp.17~25 (2007)
- Suh, I., "Alcohol use and mortality from coronary heart disease: The role of high density lipoprotein cholesterol. The Multiple Risk Factor Intervention Trial Research Group", Annals of Internal Medicine, 116(11), pp.881~887 (1992)
- Xiao, J. Q., "The diagnosis and management of solvent-related disorders", American Journal of Industrial Medicine, 37, pp.44~61 (2000)