유전자 칩 및 다변량 분석방법을 이용한 사상체질 유전자 선별에 관한 연구
A Study on Sasang Constitutional Gene Selection Using DNA Chips by Multivariate Analysis
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Abstract
A Study on Sasang Constitutional Gene Selection Using DNA Chips by Multivariate Analysis Kim Pan-Joon, Seo Eun-Hee, Lee Jung-Hwan, Ha Jin-Ho, Choi Hong-Sik*, Jung Tae-Young**, Goo Deok-Mo Dept. of Constitutional Medicine, College of Oriental Medicine, Daegu Haany Univ. *Dept. of Internal Medicine, College of Oriental Medicine, Daegu Haany Univ. **Jaehan Hospital, College of Oriental Medicine, Daegu Haany Univ. 1. Objectives This research uses the DNA chip, which includes 16,383 gene code, and various statistic prediction way that shows objectification index for the objectification of constitution diagnosis. 2. Methods Drawing blood whose constitution is confirmed, and analyze its gene information by using 1.7k DNA chip to find the gene correlation through multivariate statistical method. 3. Results and Conclusions Distinctive genes such as AK001919, U09384, NM_001805, X99962, NM_004796, AK026738, AL050148, BC002538, AK027074, AK026219, AF087962, AL390142, NM_015372, AL157466, NM_002446, AK024523, NM_014706, NM_014746 and AL137544 were related to Taeumin; AL157448, NM_005957, NM_005656, NM_017548, AK027246, NM_003025, NM_012302 and NM_005905 were represented in Soeumin, while AK026503, AF147325, NM_002076, AF147307, AK001375, NM_003740, NM_005114, AB007890, NM_005505, NM_015900, NM_014936, Z70694, AB023154, U52076, NM_004360, NM_005835, NM_017528, AF087987, NM_014897, AK021720, NM_006420, AJ277915, AK002118 and AK021918 were for Soyangin. This study figured out the possibility to develop the prediction system by sorting each constitution`s gene, and research each constitution`s distinctive character of manifestation pattern.
참고문헌 (14)
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