족부족관절 질환에서 히알루론산과 혈소판 풍부 혈장 주사치료
Hyaluronic Acid and Platelet-Rich Plasma Injections in Foot and Ankle Disorders
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초록
Numerous nonoperative treatments have been used to reduce pain and improve the clinical outcomes of patients with foot and ankle disorders. Among these treatments, hyaluronic acid and platelet-rich plasma (PRP) injections have been used increasingly. This review analyzes the recent literature reporting the efficacy and indications for hyaluronic acid and PRP injections. Hyaluronic acid and PRP can be used safely as adjuncts. Hyaluronic acid injections have shown efficacy and have a promising role as an adjuvant treatment method. In addition, its indication has expanded to various foot and ankle diseases over osteoarthritis. On the other hand, the efficacy of PRP injection has not yet been clarified, and the lack of standardization of procedures for the preparation and administration of PRP makes it difficult to establish definitive treatment indications.
Abstract
Numerous nonoperative treatments have been used to reduce pain and improve the clinical outcomes of patients with foot and ankle disorders. Among these treatments, hyaluronic acid and platelet-rich plasma (PRP) injections have been used increasingly. This review analyzes the recent literature reporting the efficacy and indications for hyaluronic acid and PRP injections. Hyaluronic acid and PRP can be used safely as adjuncts. Hyaluronic acid injections have shown efficacy and have a promising role as an adjuvant treatment method. In addition, its indication has expanded to various foot and ankle diseases over osteoarthritis. On the other hand, the efficacy of PRP injection has not yet been clarified, and the lack of standardization of procedures for the preparation and administration of PRP makes it difficult to establish definitive treatment indications.
참고문헌 (72)
- David J. Keene, "PATH-2 Trial group. Platelet-rich plasma injection for acute Achilles tendon rupture : two-year follow-up of the PATH-2 randomized, placebo-controlled, superiority trial", Bone Joint J, 104-B(11), pp.1256~1265 (2022), British Editorial Society of Bone & Joint Surgery[DOI]
- Gun-Woo Lee, "Effects and Safety of Intra-Articular Sodium Hyaluronate Injection for the Treatment of Ankle Osteoarthritis: A Prospective Clinical Trial", The Journal of Foot and Ankle Surgery, 61(2), pp.345~349 (2022), Elsevier BV[DOI]
- 송하헌, "족부족관절 질환에서 주사 치료는 얼마나 효과가 있는가?", 대한족부족관절학회지, 25(1), pp.10~16 (2021), 대한족부족관절학회[DOI]
- Le ADK, "Current clinical recommendations for use of platelet-rich plasma", Curr Rev Musculoskelet Med, 11, pp.624~634 (2018)[DOI]
- Sabino Padilla, "Platelet-Rich Plasma Applications for Achilles Tendon Repair: A Bridge between Biology and Surgery", International Journal of Molecular Sciences, 22(2), pp.824~ (2021), MDPI AG[DOI]
- Xi-Liang Shang, "Clinical and MRI outcomes of HA injection following arthroscopic microfracture for osteochondral lesions of the talus", Knee Surgery, Sports Traumatology, Arthroscopy, 24(4), pp.1243~1249 (2015), Wiley[DOI]
- Paul Creamer, "Osteoarthritis", The Lancet, 350(9076), pp.503~509 (1997), Elsevier BV[DOI]
- Angelique GH Witteveen, "Hyaluronic acid and other conservative treatment options for osteoarthritis of the ankle", Cochrane Database of Systematic Reviews, 2015(10), pp.CD010643~ (2015), Wiley[DOI]
- Gianluca Testa, "Intra-Articular Injections in Knee Osteoarthritis: A Review of Literature", Journal of Functional Morphology and Kinesiology, 6(1), pp.15~ (2021), MDPI AG[DOI]
- Wan-Hsin Chang, "Applications of Hyaluronic Acid in Ophthalmology and Contact Lenses", Molecules, 26(9), pp.2485~ (2021), MDPI AG[DOI]
- RD Altman, "The mechanism of action for hyaluronic acid treatment in the osteoarthritic knee: a systematic review", BMC Musculoskeletal Disorders, 16(1), pp.321~ (2015), Springer Science and Business Media LLC[DOI]
- Juliana Davies de Oliveira, "Genetic basis for hyper production of hyaluronic acid in natural and engineered microorganisms", Microbial Cell Factories, 15(1), pp.119~ (2016), Springer Science and Business Media LLC[DOI]
- Mat Nicholls, "A Comparison Between Rheological Properties of Intra-articular Hyaluronic Acid Preparations and Reported Human Synovial Fluid", Advances in Therapy, 35(4), pp.523~530 (2018), Springer Science and Business Media LLC[DOI]
- Charles D. Hummer, "High molecular weight Intraarticular hyaluronic acid for the treatment of knee osteoarthritis: a network meta-analysis", BMC Musculoskeletal Disorders, 21(1), pp.702~ (2020), Springer Science and Business Media LLC[DOI]
- Alastair S.E. Younger, "Nonanimal Hyaluronic Acid for the Treatment of Ankle Osteoarthritis: AProspective, Single-Arm Cohort Study", The Journal of Foot and Ankle Surgery, 58(3), pp.514~518 (2019), Elsevier BV[DOI]
- Christopher Jantzen, "The Effect of a Single Hyaluronic Acid Injection in Ankle Arthritis: A Prospective Cohort Study", The Journal of Foot and Ankle Surgery, 59(5), pp.961~963 (2020), Elsevier BV[DOI]
- Evelyn P. Murphy, "Prospective Evaluation of Intra-Articular Sodium Hyaluronate Injection in the Ankle", The Journal of Foot and Ankle Surgery, 56(2), pp.327~331 (2017), Elsevier BV[DOI]
- Michael M. Cohen, "Safety and efficacy of intra-articular sodium hyaluronate (Hyalgan) in a randomized, double-blind study for osteoarthritis of the ankle", Foot Ankle Int, 29(7), pp.657~663 (2008), SAGE Publications[DOI]
- Shu-Fen Sun, "The Effect of Three Weekly Intra-Articular Injections of Hyaluronate on Pain, Function, and Balance in Patients with Unilateral Ankle Arthritis", Journal of Bone and Joint Surgery, 93(18), pp.1720~1726 (2011), Ovid Technologies (Wolters Kluwer Health)[DOI]
- Deianira Luciani, "Viscosupplementation for grade II osteoarthritis of the ankle: a prospective study at 18 months’ follow-up", La Chirurgia degli Organi di Movimento, 92(3), pp.155~160 (2008), Springer Science and Business Media LLC[DOI]
- Mei-Dan O, "Treatment of osteoarthritis of the ankle by intra-articular injections of hyaluronic acid : a prospective study", J Am Podiatr Med Assoc, 100, pp.93~100 (2010)
- Mohit Bhandari, "Intra-articular hyaluronic acid in the treatment of knee osteoarthritis: a Canadian evidence-based perspective", Therapeutic Advances in Musculoskeletal Disease, 9(9), pp.231~246 (2017), SAGE Publications[DOI]
- V. Legré-Boyer, "Viscosupplementation: Techniques, indications, results", Orthop Traumatol Surg Res, 101(1 Suppl), pp.S101~S108 (2015), Elsevier BV[DOI]
- Jeffrey E. Johnson, "Corticosteroid Injections in the Treatment of Foot & Ankle Disorders: An AOFAS Survey", Foot Ankle Int, 32(4), pp.394~399 (2011), SAGE Publications[DOI]
- Yoshihiro Nishida, "Sustained-release diclofenac conjugated to hyaluronate (diclofenac etalhyaluronate) for knee osteoarthritis: a randomized phase 2 study", Rheumatology, 60(3), pp.1435~1444 (2020), Oxford University Press (OUP)[DOI]
- Toshikazu Kubo, "Diclofenac–hyaluronate conjugate (diclofenac etalhyaluronate) intra-articular injection for hip, ankle, shoulder, and elbow osteoarthritis: a randomized controlled trial", BMC Musculoskeletal Disorders, 23(1), pp.371~ (2022), Springer Science and Business Media LLC[DOI]
- Leonardo Osti, "Hyaluronic acid increases tendon derived cell viability and collagen type I expression in vitro: Comparative study of four different Hyaluronic acid preparations by molecular weight", BMC Musculoskeletal Disorders, 16(1), pp.284~ (2015), Springer Science and Business Media LLC[DOI]
- Julian E. Dilley, "Hyaluronic acid as an adjunct to microfracture in the treatment of osteochondral lesions of the talus: a systematic review of randomized controlled trials", BMC Musculoskeletal Disorders, 23(1), pp.313~ (2022), Springer Science and Business Media LLC[DOI]
- Angelo Boffa, "Evidence on ankle injections for osteochondral lesions and osteoarthritis: a systematic review and meta-analysis", International Orthopaedics, 45(2), pp.509~523 (2020), Springer Science and Business Media LLC[DOI]
- Yeok Gu Hwang, "Intra-articular Injections of Hyaluronic Acid on Osteochondral Lesions of the Talus After Failed Arthroscopic Bone Marrow Stimulation", Foot Ankle Int, 41(11), pp.1376~1382 (2020), SAGE Publications[DOI]
- M. N. Doral, "Treatment of osteochondral lesions of the talus with microfracture technique and postoperative hyaluronan injection", Knee Surgery, Sports Traumatology, Arthroscopy, 20(7), pp.1398~1403 (2011), Wiley[DOI]
- Omer Mei-Dan, "Platelet-Rich Plasma or Hyaluronate in the Management of Osteochondral Lesions of the Talus", The American Journal of Sports Medicine, 40(3), pp.534~541 (2012), SAGE Publications[DOI]
- Francesco Oliva, "The Impact of Hyaluronic Acid on Tendon Physiology and Its Clinical Application in Tendinopathies", Cells, 10(11), pp.3081~ (2021), MDPI AG[DOI]
- Tsukasa Kumai, "The short-term effect after a single injection of high-molecular-weight hyaluronic acid in patients with enthesopathies (lateral epicondylitis, patellar tendinopathy, insertional Achilles tendinopathy, and plantar fasciitis): a preliminary study", Journal of Orthopaedic Science, 19(4), pp.603~611 (2014), Elsevier BV[DOI]
- N. Sawaguchi, "Extracellular Matrix Modulates Expression of Cell-Surface Proteoglycan Genes in Fibroblasts", Connective Tissue Research, 47(3), pp.141~148 (2006), Informa UK Limited[DOI]
- Tsukasa Kumai, "Short-term efficacy and safety of hyaluronic acid injection for plantar fasciopathy", Knee Surgery, Sports Traumatology, Arthroscopy, 26(3), pp.903~911 (2017), Wiley[DOI]
- Michael J. Petrella, "Original Research: Long-Term Efficacy and Safety of Periarticular Hyaluronic Acid in Acute Ankle Sprain", The Physician and Sportsmedicine, 37(1), pp.64~70 (2009), Informa UK Limited[DOI]
- Ilaria Repetto, "Conservative Treatment of Ankle Osteoarthritis: Can Platelet-Rich Plasma Effectively Postpone Surgery?", The Journal of Foot and Ankle Surgery, 56(2), pp.362~365 (2017), Elsevier BV[DOI]
- Kang Lee, "Ultrasound-Guided Hyaluronic Acid Injection for the Management of Morton’s Neuroma", Foot Ankle Int, 39(2), pp.201~204 (2017), SAGE Publications[DOI]
- C. CARULLI, "Viscosupplementation in haemophilic arthropathy: a long‐term follow‐up study", Haemophilia, 18(3), pp.e210~e214 (2011), Wiley[DOI]
- Stephanie Taylor, "A single centre, open label, pilot study evaluating the effect of intra‐articular hyaluronic acid injection on pain and functionality when injected into the ankle (tibio‐talar and sub‐talar) joint in patients with haemophilic arthropathy", Haemophilia, 28(6), pp.e181~e188 (2022), Wiley[DOI]
- 윤정용, "혈소판 풍부 혈장의 주사치료", 대한정형외과학회지, 53(5), pp.381~392 (2018), 대한정형외과학회[DOI]
- Shu-Fen Sun, "Efficacy and Safety of a Single Intra-articular Injection of Platelet-rich Plasma on Pain and Physical Function in Patients With Ankle Osteoarthritis—A Prospective Study", The Journal of Foot and Ankle Surgery, 60(4), pp.676~682 (2021), Elsevier BV[DOI]
- Juancarlos Blanco-Rivera, "Treatment of lateral ankle sprain with platelet-rich plasma: A randomized clinical study", Foot and Ankle Surgery, 26(7), pp.750~754 (2020), Elsevier BV[DOI]
- Peter R. Henning, "Platelet-rich plasma in the foot and ankle", Current Reviews in Musculoskeletal Medicine, 11(4), pp.616~623 (2018), Springer Science and Business Media LLC[DOI]
- M. Ferrari, "A new technique for hemodilution, preparation of autologous platelet-rich plasma and intraoperative blood salvage in cardiac surgery", The International Journal of Artificial Organs, 10(1), pp.47~50 (1987), SAGE Publications[DOI]
- Anitua E, "Plasma rich in growth factors : preliminary results of use in the preparation of future sites for implants", Int J Oral Maxillofac Implants, 14, pp.529~535 (1999)
- M. Kawasumi, "The effect of the platelet concentration in platelet-rich plasma gel on the regeneration of bone", The Journal of Bone and Joint Surgery. British volume, 90-B(7), pp.966~972 (2008), British Editorial Society of Bone & Joint Surgery[DOI]
- L Creaney, "Growth factor delivery methods in the management of sports injuries: the state of play", British Journal of Sports Medicine, 42(5), pp.314~320 (2008), BMJ[DOI]
- Voja Pavlovic, "Platelet Rich Plasma: a short overview of certain bioactive components", Open Medicine, 11(1), pp.242~247 (2016), Walter de Gruyter GmbH[DOI]
- Wen‐Chung Tsai, "Platelet rich plasma promotes skeletal muscle cell migration in association with up‐regulation of FAK, paxillin, and F‐Actin formation", Journal of Orthopaedic Research, 35(11), pp.2506~2512 (2017), Wiley[DOI]
- Eduardo Anitua, "Autologous platelets as a source of proteins for healing and tissue regeneration", Thrombosis and Haemostasis, 91(01), pp.4~15 (2004), Georg Thieme Verlag KG[DOI]
- Robert E. Marx, "Platelet-Rich Plasma (PRP): What Is PRP and What Is Not PRP?", Implant Dentistry, 10(4), pp.225~228 (2001), Ovid Technologies (Wolters Kluwer Health)[DOI]
- Yunus Guzel, "The biomechanical and histological effects of platelet-rich plasma on fracture healing", Knee Surgery, Sports Traumatology, Arthroscopy, 23(5), pp.1378~1383 (2013), Wiley[DOI]
- Liam D. A. Paget, "Effect of Platelet-Rich Plasma Injections vs Placebo on Ankle Symptoms and Function in Patients With Ankle Osteoarthritis", JAMA, 326(16), pp.1595~1605 (2021), American Medical Association (AMA)[DOI]
- Rebecca S. Kearney, "Effect of Platelet-Rich Plasma Injection vs Sham Injection on Tendon Dysfunction in Patients With Chronic Midportion Achilles Tendinopathy", JAMA, 326(2), pp.137~144 (2021), American Medical Association (AMA)[DOI]
- Erik Hohmann, "Platelet-Rich Plasma Versus Corticosteroids for the Treatment of Plantar Fasciitis: A Systematic Review and Meta-analysis", The American Journal of Sports Medicine, 49(5), pp.1381~1393 (2020), SAGE Publications[DOI]
- Oleg Dolkart, "A single dose of platelet-rich plasma improves the organization and strength of a surgically repaired rotator cuff tendon in rats", Archives of Orthopaedic and Trauma Surgery, 134(9), pp.1271~1277 (2014), Springer Science and Business Media LLC[DOI]
- Suzan de Jonge, "One-Year Follow-up of Platelet-Rich Plasma Treatment in Chronic Achilles Tendinopathy", The American Journal of Sports Medicine, 39(8), pp.1623~1630 (2011), SAGE Publications[DOI]
- Robert J. de Vos, "Platelet-rich plasma injection for chronic Achilles tendinopathy: a randomized controlled trial", JAMA, 303(2), pp.144~149 (2010), American Medical Association (AMA)[DOI]
- Thøger P. Krogh, "Ultrasound-guided injection therapy of Achilles tendinopathy with plateletrich plasma or saline: a randomized, blinded, placebo-controlled trial", The American Journal of Sports Medicine, 44(8), pp.1990~1997 (2016), SAGE Publications[DOI]
- Mr Imad Madhi, "The use of PRP in treatment of Achilles Tendinopathy: A systematic review of literature. Study design: Systematic review of literature", Annals of Medicine and Surgery, 55, pp.320~326 (2020), Ovid Technologies (Wolters Kluwer Health)[DOI]
- Thorsten Schepull, "Autologous platelets have no effect on the healing of human achilles tendon ruptures: a randomized single-blind study", The American Journal of Sports Medicine, 39(1), pp.38~47 (2010), SAGE Publications[DOI]
- Nicole Kaniki, "A Retrospective Comparative Study With Historical Control to Determine the Effectiveness of Platelet-Rich Plasma as Part of Nonoperative Treatment of Acute Achilles Tendon Rupture", Arthroscopy, 30(9), pp.1139~1145 (2014), Elsevier BV[DOI]
- Anders Ploug Boesen, "Effect of Platelet-Rich Plasma on Nonsurgically Treated Acute Achilles Tendon Ruptures: A Randomized, Double-Blinded Prospective Study", The American Journal of Sports Medicine, 48(9), pp.2268~2276 (2020), SAGE Publications[DOI]
- Sumit Kumar Jain, "Comparison of Plantar Fasciitis Injected With Platelet-Rich Plasma vs Corticosteroids", Foot Ankle Int, 39(7), pp.780~786 (2018), SAGE Publications[DOI]
- Lior Laver, "Plasma rich in growth factors (PRGF) as a treatment for high ankle sprain in elite athletes: a randomized control trial", Knee Surgery, Sports Traumatology, Arthroscopy, 23(11), pp.3383~3392 (2014), Wiley[DOI]
- Taisuke Fukawa, "Safety and Efficacy of Intra-articular Injection of Platelet-Rich Plasma in Patients With Ankle Osteoarthritis", Foot Ankle Int, 38(6), pp.596~604 (2017), SAGE Publications[DOI]
- Ahmet Guney, "Clinical outcomes of platelet rich plasma (PRP) as an adjunct to microfracture surgery in osteochondral lesions of the talus", Knee Surgery, Sports Traumatology, Arthroscopy, 23(8), pp.2384~2389 (2013), Wiley[DOI]
- Gökay Görmeli, "Clinical Effects of Platelet-Rich Plasma and Hyaluronic Acid as an Additional Therapy for Talar Osteochondral Lesions Treated with Microfracture Surgery", Foot Ankle Int, 36(8), pp.891~900 (2015), SAGE Publications[DOI]
- Gustaaf Reurink, "Dutch Hamstring Injection Therapy (HIT) Study Investigators. Platelet-rich plasma injections in acute muscle injury", New England Journal of Medicine, 370(26), pp.2546~2547 (2014), Massachusetts Medical Society[DOI]
- Alice Roffi, "Platelet-rich plasma for the treatment of bone defects: from pre-clinical rational to evidence in the clinical practice. A systematic review", International Orthopaedics, 41(2), pp.221~237 (2016), Springer Science and Business Media LLC[DOI]
