북한산 둘레길에서 참진드기의 계절적 발생과 중증열성혈소판감소증후군 바이러스 검출
Seasonal Prevalence of Ticks at Bukhansan Dullegil and Detection of Severe Fever with Thrombocytopenia Syndrome Virus
2
조회
0
다운로드
0
인용
0
참고문헌
키워드
초록
2019년 4월부터 10월까지 북한산 둘레길 12구간(지축동), 14구간(울대리), 18구간(호원동)에서 참진드기를 채집해서 계절적 분포 조사와 매개체의 SFTS 바이러스 감염 여부를 확인하였다. 천젓기와 천끌기 방법으로 개피참진드기, 일본참진드기와 중증열성혈소판감소증후군의 주된 매개체로 알려진 작은소피참진드기 3종이 채집되었다. 작은소피참진드기는 채집비율이 지축동 91%, 울대리 94%, 호원동 98%를 차지하여 우점종이었다. 작은소피참진드기의 성숙단계에 따른 계절별 채집비율을 보면 성충의 경우 세 지역 모두 9월에 최고치를 보였고 약충의 경우에는 4월에서 6월 사이에 주로 채집되었다. 유충의 경우에는 9월과 10월에 최고치를 보였다. 채집된 작은소피참진드기 1,158개체를 성숙단계별로 2× OneStep RT-PCR과 nested PCR로 SFTS 바이러스 검사를 한 결과 양성은 나타나지 않았다. 2010년 개장 이후 이용객이 늘어나는 북한산 둘레길에서 기후 온난화로 증가가 예상되는 참진드기 매개 질환에 대한 위험분석과 효율적인 예방에 본 조사 결과가 활용될 수 있다.
Abstract
The study examined the seasonal pattern of larvae, nymph, and adult life stages for Haemaphysalis longicornis and the rate of infection with severe fever from the thrombocytopenia syndrome virus in ticks collected from 12 sections (Jichukdong), 14 sections (Uldaeri), and 18 sections (Howondong) in Bukhansan dullegil for April–October 2019. Haemaphysalis longicornis ticks have been considered the main vector for severe fever with thrombocytopenia syndrome (SFTS). Haemaphysalis flava and Ixodes nipponensis were collected using the dragging and flagging method. The ratios of Haemaphysalis longicornis of the collected ticks were 91% (Jichukdong), 94% (Uldaeri), and 98% (Howondong). Monthly distributional studies of Haemaphysalis longicornis based on the developmental stage showed that the adults peaked in September while nymphs were collected more frequently from April through June. The larvae peaked in September and October. SFTS virus detection was performed using 2 × OneStep RT-PCR and nested PCR. On the other hand, no SFTS virus-specific gene was detected in 1,158 ticks of Haemaphysalis longicornis. This result provides estimates of the population densities for the life stages of Haemaphysalis longicornis and the associated disease risk in Bukhansan dullegil, where many people have visited since opening in 2010.
참고문헌 (23)
- 설형, "국내 진드기매개 질환의 현황과 전망", 대한의사협회지, 60(6), pp.475~483 (2017), 대한의사협회[DOI]
- 김계형, "중증열성혈소판감소증후군", 대한내과학회지, 86(3), pp.271~276 (2014), 대한내과학회[DOI]
- Ding F, "Epidemiologic features of severe fever with thrombocytopenia syndrome in China, 2011-2012", Clin Infect Dis, 56, pp.1682~1683 (2013)[DOI]
- Takahashi T, "The first identification and retrospective study of severe fever with thrombocytopenia syndrome in Japan", J Infect Dis, 209, pp.816~827 (2014)[DOI]
- Zhang YZ, "Hemorrhagic fever caused by a novel Bunyavirus in China : pathogenesis and correlates of fatal outcome", Clin Infect Dis, 54, pp.527~533 (2012)[DOI]
- Jaeseung Shin, "Characteristics and Factors Associated with Death among Patients Hospitalized for Severe Fever with Thrombocytopenia Syndrome, South Korea, 2013", Emerging Infectious Diseases, 21(10), pp.1704~1710 (2015), Centers for Disease Control and Prevention (CDC)[DOI]
- Noh BE, "Geographical distribution of ticks in the Republic of Korea in 2018", Osong Public Health Res Perspect, 11, pp.1417~1421 (2018)
- 조우현, "북한산 둘레길 이용객 만족도에 관한 연구", 한국조경학회지, 39(4), pp.60~73 (2011), 한국조경학회
- Yamaguti N, "Ticks of Japan, Korea and the Ryukyu Islands", Brigham Young Univ Sci Bull, 15, pp.1~226 (1971)
- Egizi AM, "A pictorial key to differentiate the recently detected exotic Haemaphysalis longicornis Neumann, 1901(Acari, Ixodidae)from native congeners in North America", Zookeys, 818, pp.117~128 (2019)
- Seok-Min Yun, "Severe Fever with Thrombocytopenia Syndrome Virus in Ticks Collected from Humans, South Korea, 2013", Emerging Infectious Diseases, 20(8), pp.1358~1361 (2014), Centers for Disease Control and Prevention (CDC)[DOI]
- Jung M, "Seasonal occurrence of Haemaphysalis longicornis(Acari : Ixodidae)and Haemaphysalis flava, vectors of severe fever with thrombocytopenia syndrome(SFTS)in South Korea", J Med Entomol, 56, pp.1139~1144 (2019)[DOI]
- Noh YT, "Molecular detection for tick-borne pathogens in hard ticks collected in Gangwon and Jeju-do, 2014", Osong Public Health Res Perspect, 7, pp.1071~1076 (2014)
- 송병준, "지리산둘레길에서 채집한 참진드기의 분포와 참진드기에서의 중증열성혈소판감소증후군바이러스 검출", 한국동물위생학회지, 39(2), pp.75~80 (2016), 한국동물위생학회
- 신용칠, "경기도 포천, 강원도 철원지역에서 진드기의 계절적 발생 유형", 대한임상검사과학회지, 47(3), pp.147~152 (2015), 대한임상검사과학회
- Kim JH, "Infection control of severe fever with thrombocytopenia syndrome in hospital settings and comprehensive reviews of nosocomial infectious in South Korea", Osong Public Health Res Perspect, 11, pp.286~289 (2018)
- 김다영, "한국의 흔한 진드기 매개 감염병: 쯔쯔가무시병과 중증열성혈소판감소증후군", 대한내과학회지, 93(5), pp.416~423 (2018), 대한내과학회
- Shelan Liu, "Systematic review of severe fever with thrombocytopenia syndrome:virology, epidemiology, and clinical characteristics", Reviews in Medical Virology, 24(2), pp.90~102 (2014), Wiley[DOI]
- Kye-Hyung Kim, "Severe Fever with Thrombocytopenia Syndrome, South Korea, 2012", Emerging Infectious Diseases, 19(11), pp.1892~1894 (2013), Centers for Disease Control and Prevention (CDC)[DOI]
- Seo CW, "Epidemiological characteristics of patients with severe fever with thrombocytopenia syndrome in Republic Korea in 2017", Osong Public Health Res Perspect, 11, pp.698~706 (2018)
- 채정병, "관악산에서 참진드기 조사 및 중증열성혈소판감소증후군 바이러스 검출", 대한수의학회지, 57(3), pp.169~174 (2017), 대한수의학회[DOI]
- Kim SY, "Density and SFTS virus infection rates of ixodid in Gochang-gun, Jeollabuk-do, South Korea, 2016", Osong Public Health Res Perspect, 10, pp.1266~1270 (2017)
- Patricia V. Aguilar, "The Emergence of Severe Fever with Thrombocytopenia Syndrome Virus", The American Journal of Tropical Medicine and Hygiene, 97(4), pp.992~996 (2017), American Society of Tropical Medicine and Hygiene[DOI]