Korean Medicinal Herb Extracts Inhibit Melanin Formation in Clone M-3 Mouse Melanocyte Cell Lines
2
조회
0
다운로드
1
인용
0
참고문헌
초록
Abstract
- In order to search for anti -melanin formation agents from Korean medic-inal herbs, we selected 21 Korean medicinal herbs, based on a review of Korean tradi-tional medicine books and the recommendations of Korean traditional medicaldoctors. We tested for inhibition effect of melanin pigmentation of Clone M-3 mousemelanocyte cell lines when we treated the extracts of 21 medicinal herbs in the mousemelanocyte cell lines, respectively. Among 21 medicinal herb extracts, 5 extractsshowed a inhibition effect of melanin formation. The sample Phaseolus radiatus L,Cordyceps militaris, Pinellia ternata, Phellinus linteus and Citrus junos Tanaka showeda significantly little formation of melanin pigments compared with control groups.Especially extract of Citrus junos Tanaka was more potent than the others. Theseresults suggest that extract of Korean Citrus junos may represents an excellentcandidate for inhibition of melanin pigmentation at in vitro level.
참고문헌 (12)
- Chait A, "Clinical and metabolic study of alcoholic hyperlipidermia", pp.62~2 64 (1972)
- Choi HC, "Evluation of skin furrows inthe aging process using an image analysis system", 35, pp.292~302 (1997)
- Han KW, "Theeffect of sulfhydryl compounds on melanosomal morphologyof epidermal melanocytes in UV-irradiatedblack mice", pp.553~561 (1987)
- Han KH, "Histological changes in the skin with innate aging", 36, pp.971~980 (1998)
- Huh J, "Young In Bon", pp.379~422 (1981), Hang-SungBook Press
- Kang SW, "Pharmacology and molecular action of retinoids andvitamin D in skin", 1((1), pp.15~21 (1996)
- Kim YK, "The effect of UV- Bradiation on epidermal melanocytes of C57BL Mouse", pp.139~144 (1988)
- Kim YH, "Effects ofPanax Ginseng and Radix Astragali on age-relatedphysiological alterations in rats", pp.26~46 (1989)
- Koo SW, "The effects of ultraviolet radiation on aging and p53expression in human skin", 36, pp.224~235 (1998)
- Robert M, "A study by light", pp.44~51 (1987)
- Lee OS, "Studies onthe synthesis of L-Ascorbic acid-3-aminopropanephosphoric acid diester and its applications", 23, pp.97~109 (1997)
- Yoon KY, "Clinical Prescriptions of Korean traditionalmedicals" (1992), Myung Bo Publishing