물벼룩 (Daphnia magna)에서 내분비계장애물질인 노닐페놀의 영향
Effects of Endocrine Disruptors, Nonylphenol in Daphnia magna
1
조회
0
다운로드
1
인용
0
참고문헌
키워드
초록
Nonylphenol is one of endocrine disruptors, as structurally stable, hydrophobic compounds exhibit high condensability and long-lasting in the natural environment. The purpose of this study was to determine the toxic effects of nonylphenol on Daphnia magna. In acute toxicity test, D. magna was exposed for 48 h at concentrations of 0, 10, 18, 32, 56 and 100 μg L-1 nonylphenol. In chronic toxicity test, D. magna were exposed through water for 21 days at concentrations of 0, 1.0, 1.8, 3.2, 5.6 and 10 μg L-1 nonylphenol. Acute toxicity was assessed on the basis of immobility, while chronic toxicity was assessed on the basis of fecundity. The acute toxicity test on nonylphenol was showed that the values of 24 h and 48 h EC50 were 25.0 μg L-1 and 13.7 μg L-1, respectively. In chronic test, fecundity was reduced significantly at 5.6 μg L-1 of nonylphenol. These results indicated that nonylphenol have some hazard for acute or chronic toxicity to freshwater invertebrate organism.
Abstract
Nonylphenol is one of endocrine disruptors, as structurally stable, hydrophobic compounds exhibit high condensability and long-lasting in the natural environment. The purpose of this study was to determine the toxic effects of nonylphenol on Daphnia magna. In acute toxicity test, D. magna was exposed for 48 h at concentrations of 0, 10, 18, 32, 56 and 100 μg L-1 nonylphenol. In chronic toxicity test, D. magna were exposed through water for 21 days at concentrations of 0, 1.0, 1.8, 3.2, 5.6 and 10 μg L-1 nonylphenol. Acute toxicity was assessed on the basis of immobility, while chronic toxicity was assessed on the basis of fecundity. The acute toxicity test on nonylphenol was showed that the values of 24 h and 48 h EC50 were 25.0 μg L-1 and 13.7 μg L-1, respectively. In chronic test, fecundity was reduced significantly at 5.6 μg L-1 of nonylphenol. These results indicated that nonylphenol have some hazard for acute or chronic toxicity to freshwater invertebrate organism.
참고문헌 (37)
- 방현우, "4-Nonylphenol에 노출된 저서성 요각류 Tigriopus japonicus s.l.의 생활사, 형태와 유전자 발현", 생태와 환경, 41(1), pp.81~89 (2008), 한국하천호수학회
- Campos B., "Enhanced offspring production in Daphnia magna clones exposed to serotonin reuptake inhibitors and 4-nonylphenol. Stage-and food-dependent effects", Aquat. Toxicol, 109, pp.100~110 (2012)
- 조형구, "조피볼락(Sebastes schlegeli)의 Retinol-Binding Protein의 유전자 발현에 미치는 4-Nonylphenol의 영향", 발생과 생식, 10(3), pp.177~184 (2006), 한국발생생물학회
- 조남국, "Nonylphenol의 장기간 노출에 의한 붕어, Carassius auratus의 생식지표 변화", 환경독성보건학회지, 22(3), pp.235~245 (2007), 환경독성보건학회
- Choi SB., "Human and Environment", pp.264~270 (2007), Donghwa Technology Publishing Co
- Comber MHI., "The Effects of Nonylphenol on Daphnia magna", War. Res, 27, pp.273~276 (1993)
- LeBlanc GA., "Embryotoxicity of the Alkylphenol Degradation Product 4-Nonylphenol to the Crustacean Daphnia magna", Environ. Health Perspect, 108, pp.1133~1138 (2000)
- 함영국, "상수도 계통에서 비스페놀 A와 노닐페놀의 실태조사", 분석과학, 17(5), pp.423~433 (2004), 한국분석과학회
- 황인준, "Bisphenol A와 nonylphenol이 노래미, Hexagrammos agrammus 성숙기 난모세포의 스테로이드 생성과정에 미치는 영향", 발생과 생식, 12(3), pp.275~281 (2008), 한국발생생물학회
- Janicki T., "Degradation and toxicity reduction of the endocrine disruptors nonylphenol, 4-tert-octylphenol and 4-cumylphenol by the non-ligninolytic fungus Umbelopsis isabellina", Bioresour. Technol, 200, pp.223~229 (2015)
- Ju MJ., "Distribution of organotins, NP and BPA in sediment of intertidal zone around the south coast of Korea.", J. Korean Assoc. Ocean Sc. Technol. Soc, pp.2270~ (2014)
- 김지혜, "4-t-octylphenol과 nonylphenol이 등줄쥐의 번식에 미치는 영향", 한국환경과학회지, 23(2), pp.313~322 (2014), 한국환경과학회[DOI]
- 김경태, "Daphnia magna를 이용한 과불화화합물의 독성평가", 환경독성보건학회지, 25(2), pp.153~160 (2010), 환경독성보건학회
- Kim MY., "Biology concepts & connections", pp.443~444 (2004), Life Science Publishing Co
- Kim SY., "A study of the distribution and transport of Nonylphenol on the Suyeong river mouth", J. Korean Soc. Mar. Environ. Saf, pp.387~388 (2012)
- Chemical emissions, the amount of movement Investigation Report, "Korea Ministry of Environment.", 28~29 (2012)
- Chemical emissions, the amount of movement Investigation Report, "Korea Ministry of Environment.", 32~33 (2014)
- Korea Ministry of Environment., "Act on the Registration and Evaluation, etc. of Chemical Substances", ~ (2015)
- Korea Ministry of Health & Welfare., "PUBLIC HEALTH CONTROL ACT", ~ (2013)
- Korsman JC., "Modeling bioaccumulation and biomagnification of nonylphenol and its ethoxylates in estuarine-marine food chains", Chemosphere, 138, pp.33~39 (2015)
- Lee CC., "Characteristics of nonylphenol and bisphenol A accumulation by Fish and implications for ecological and human health", Sci. Total Environ, 502, pp.417~425 (2015)
- 이철우, "Nonylphenol과 Bisphenol A의 지렁이 독성시험 및 토양 중 생태 위해성평가", 환경독성보건학회지, 20(4), pp.279~286 (2005), 환경독성보건학회
- Lee JH., "Contaminations of organotin compounds, nonylphenol and bisphenol-A in sediments of Masan bay", J. Korean Soc. Mar. Environ. Engin, 4, pp.28~35 (2004)
- 이주한, "내분비장애물질 Nonylphenol이 미세조류, 종속영양편모충, 동물플랑크톤의 개체군 성장에 미치는 영향", 생태와 환경, 40(3), pp.379~386 (2007), 한국하천호수학회
- Liu Y., "Toxicity of the xenoestrogen nonylphenol and its biodegradation by the alga Cyclotella caspia", J. Environ. Sci, 25, pp.1662~1671 (2013)
- OECD Guideline for testing of chemicals; Daphnia magna Reproduction Test (TG211), "Organization for Economic Co-operation and Development (OECD).", ~ (1998)
- Organization for Economic Co-operation and Development(OECD)., "OECD Guideline for testing of chemicals", Acute immobilisation test(TG202), ~ (2004)
- 박지선, "노닐페놀에 노출된 바지락, Ruditapes philippinarum의 생식 및 조직학적 지표 변화", The Korean Journal of Malacology, 27(3), pp.181~190 (2011), 한국패류학회
- 박광일, "내분비교란물질인 Nonylphenol과 DEHP(Di-(2ethylhexyl)phatalate)가 줄지렁이(Eisenia fetida)의 산란 및 부화에 미치는 영향", 유기물자원화, 20(2), pp.89~95 (2012), 유기성자원학회[DOI]
- Preuss TG., "Life stage-dependent bioconcentration of a nonylphenol isomer in Daphnia magna", Environ. Pollut, 156, pp.1211~1217 (2008)
- Riva C., "Evaluation of 4-nonylphenol in vivo exposure in Dreissena polymorpha : Bioaccumulation, steroid levels and oxidative stress", Comp. Biochem. Phys. C, 152, pp.175~181 (2010)
- Robertson LS., "The effect of nonylphenol on gene expression in Atlantic salmon smolts", Aquat. Toxicol, 122-123, pp.36~43 (2012)
- Schwaiger J., "Chronic toxicity of nonylphenol and ethinylestradiol : haematological and histopathological effects in juvenile Common carp(Cyprinus carpio)", Aquat. Toxicol, 51, pp.69~78 (2000)
- Soares A., "Nonylphenol in the environment : A critical review on occurrence, fate, toxicity and treatment in wastewaters", Environ. Int, 34, pp.1033~1049 (2008)
- Sung HH., "Effect of nonylphenol on giant freshwater prawn(Macrobrachium rosenbergii)via oral treatment : Toxicity., and messenger RNA expression of hemocyte genes", Aquat. Toxicol, 91, pp.270~277 (2009)
- United States Environmental Protection Agency., "Methods for measuring the acute toxicity of effluents and receiving water to freshwater and marine organisms", ~ (2002)
- Zhang L., "The effects of 4-nonylphenol and ethanol on acute toxicity, embryo development, and reproduction in Daphnia magna", Ecotoxicol. Environ. Saf, 55, pp.330~337 (2003)