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KERD
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식품 중 잔류동물용의약품의 안전관리

Management of Veterinary Drug Residues in Food

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초록

Veterinary drugs have been used to prevent livestock diseases for many years. In spite of having advantages, sometimes indiscriminate application, overdose and abuse may cause risk for human. Therefore, management and risk assessment of veterinary drugs become essential to ensure food safety. So the National Veterinary Research & Quarantine Service (NVRQS) impose on registration for use of veterinary drugs also Korea Food and Drug Administration (KFDA) fixed the maximum residue limits (MRLs) for veterinary drugs in food. Basically, KFDA set MRLs based on the veterinary drugs residual data. Moreover, KFDA estimates the theoretical maximum daily intake (TMDI) with food consumption data and population mean body weight. Recently, 116 veterinary drug MRLs including banned veterinary drugs have been established and other 32 veterinary drugs MRLs will be established within 2009. In 2010, MRLs among antibiotics and synthetic antibacterial agents in livestock fishery products (including milk and eggs) and honey (including royal jelly and propolis) which have not been set in Korea Food Code and Codex Alimentarius Commission (CAC) will be regulated as uniform limit (0.03 mg/kg). In future, veterinary drugs will be controlled strictly to strengthen public health by improving analytical method.

Abstract

Veterinary drugs have been used to prevent livestock diseases for many years. In spite of having advantages, sometimes indiscriminate application, overdose and abuse may cause risk for human. Therefore, management and risk assessment of veterinary drugs become essential to ensure food safety. So the National Veterinary Research & Quarantine Service (NVRQS) impose on registration for use of veterinary drugs also Korea Food and Drug Administration (KFDA) fixed the maximum residue limits (MRLs) for veterinary drugs in food. Basically, KFDA set MRLs based on the veterinary drugs residual data. Moreover, KFDA estimates the theoretical maximum daily intake (TMDI) with food consumption data and population mean body weight. Recently, 116 veterinary drug MRLs including banned veterinary drugs have been established and other 32 veterinary drugs MRLs will be established within 2009. In 2010, MRLs among antibiotics and synthetic antibacterial agents in livestock fishery products (including milk and eggs) and honey (including royal jelly and propolis) which have not been set in Korea Food Code and Codex Alimentarius Commission (CAC) will be regulated as uniform limit (0.03 mg/kg). In future, veterinary drugs will be controlled strictly to strengthen public health by improving analytical method.

참고문헌 (26)

  1. Report of the Thirteenth Session of the Codex Committee on Residues of Veterinary Drugs in Foods, "CCRVDF", ~ (2001)
  2. NVRQS, "Notice No. 2007-25", ~ (2008)
  3. NVRQS, "Classification for Active Ingredient of Veterinary Drug" (2004), The National Veterinary Research & Quarantine Service
  4. KAHPA, "Usage of Veterinary Drugs" (2001), Korea Animal Health Products Association
  5. MIFAFF, "Report of Control of Antibiotic Resistance in 2008", Control of Antibiotic Resistance in 2008 (2009), Korea Food & Drug Administration
  6. MIFAFF, "Notice No. 1992-13", ~ (1992)
  7. NVRQS, "Notice No. 2002-6", ~ (2002)
  8. S. H. Lee, "Control of nitrofuran veterinary drug in food", Food Industry, 202, pp.58~70 (2008)
  9. NVRQS, "Notice No. 2005-3", ~ (2005)
  10. NVRQS, "Notice No. 2008-25", ~ (2008)
  11. KFDA, "Korea Food Code" (2008), Korean Food and Drug Administration
  12. KFDA, "Notice No. 2004-18", ~ (2004)
  13. KFDA, "Notice No. 2004-81", ~ (2004)
  14. KFDA, "Advanced Notice No. 2005-99", ~ (2005)
  15. KFDA, "Notice No. 2006-35", ~ (2006)
  16. KFDA, "Advanced Notice No. 2006-222", ~ (2006)
  17. KFDA, "Notice No. 2007-63", ~ (2007)
  18. KFDA, "Notice No. 2007-68", ~ (2007)
  19. Food and Agriculture organization of the united nations world health orga, "Technical Workshop on Residues of Veterinary Drugs without ADI", MRL, FAO, Technical Workshop on Residues of Veterinary Drugs without ADI, pp.MRL, FAO, WHO[DOI]
  20. Codex Guidelines for the Establishment of Regulatory Programme for Control of Veterinary Drug Residues in Foods, CAC, "GL 16", Codex Alimentarius Committee, 1993
  21. Japan MHLW, "Notification No.499", ~ (2005)
  22. US FDA, "Code of Federal Regulation Part 530.41; Drugs prohibited for extralabel use in animals", ~
  23. European Union, "Council Regulation No. 2377", 90; A community procedure for the establishment of maximum residue limits of veterinary medicinal procuts in foodstuffs of animal origin, 1990
  24. European Commission, "Performance criteria and other requirements for analytical methods SANCO", 2004, pp.2004, ~
  25. KFDA, "Advanced Notice No. 2009-173", ~ (2009)
  26. KFDA, "Notice No. 2008-51", ~ (2008)

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