Benign Granular Cell Tumor of Interarytenoid Fold: A Case Report and Comprehensive Review in South Korea
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초록
Granular cell tumor (GCT) is a extremely rare soft tissue tumor which can mimic the histopathology of squamous cell carcinoma (SCC). The character of GCT in larynx is usually benign but malignant change could be possible. Thus, it is important to distinguish laryngeal GCT from benign disease such as granuloma, polyp, not to mention malignant disease such as laryngeal SCC. The diagnosis is done by immunohistochemistry. Treatment for GCT is surgical removal with negative margin. Although systemic review of laryngeal GCT exists abroad, our literature made the first attempt to organize 13 cases in South Korea reported since 2002. We also present our case of patient with young age but with heavy smoking history in 2023 thereby contributing to cases of GCT of larynx reported in South Korea with possible correlation with smoking.
Abstract
Granular cell tumor (GCT) is a extremely rare soft tissue tumor which can mimic the histopathology of squamous cell carcinoma (SCC). The character of GCT in larynx is usually benign but malignant change could be possible. Thus, it is important to distinguish laryngeal GCT from benign disease such as granuloma, polyp, not to mention malignant disease such as laryngeal SCC. The diagnosis is done by immunohistochemistry. Treatment for GCT is surgical removal with negative margin. Although systemic review of laryngeal GCT exists abroad, our literature made the first attempt to organize 13 cases in South Korea reported since 2002. We also present our case of patient with young age but with heavy smoking history in 2023 thereby contributing to cases of GCT of larynx reported in South Korea with possible correlation with smoking.
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