Intravascular Papillary Endothelial Hyperplasia in Hypopharynx: A Case Report
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Intravascular papillary endothelial hyperplasia (IPEH), also known as Masson’s hemangioma, is a rare benign vascular tumor. It presents as a reddish-blue firm mass, characterized by the proliferation of endothelial cells within blood vessels. IPEH can manifest in various body parts. In this article, we describe a 76-year-old male presenting intermittent oral bleeding and dysphagia. Laryngoscopy revealed a 2 cm protruding, irregular, reddish-blue, and slightly hemorrhagic tumor on the posterior hypopharyngeal wall. Computed tomography revealed a 2-cm soft tissue mass. The tumor was surgically excised using a CO<sub>2</sub> laser via suspension laryngoscopy. Histopathological examination revealed increased vascularity with papillary endothelial projections in the vascular lumen and no significant mitotic activity, leading to a diagnosis of IPEH. The patient exhibited a successful treatment outcome, with no recurrence observed over one year postoperatively. This case enhances our understanding of IPEH, emphasizing careful differential diagnosis and histopathological analyses to distinguish it from malignant lesions.
Abstract
Intravascular papillary endothelial hyperplasia (IPEH), also known as Masson’s hemangioma, is a rare benign vascular tumor. It presents as a reddish-blue firm mass, characterized by the proliferation of endothelial cells within blood vessels. IPEH can manifest in various body parts. In this article, we describe a 76-year-old male presenting intermittent oral bleeding and dysphagia. Laryngoscopy revealed a 2 cm protruding, irregular, reddish-blue, and slightly hemorrhagic tumor on the posterior hypopharyngeal wall. Computed tomography revealed a 2-cm soft tissue mass. The tumor was surgically excised using a CO<sub>2</sub> laser via suspension laryngoscopy. Histopathological examination revealed increased vascularity with papillary endothelial projections in the vascular lumen and no significant mitotic activity, leading to a diagnosis of IPEH. The patient exhibited a successful treatment outcome, with no recurrence observed over one year postoperatively. This case enhances our understanding of IPEH, emphasizing careful differential diagnosis and histopathological analyses to distinguish it from malignant lesions.
참고문헌 (12)
- Masson P, "Hemangioendotheliome vegetant intravasculaire", Bull Soc Anat Paris, 93, pp.517~523 (1923)
- Soares AB, "Intravascular papillary endothelial hyperplasia : report of 2 cases and immunohistochemical study", Oral Surg Oral Med Oral Pathol Oral Radiol Endod, 106(5), pp.708~711 (2008)
- de Courten A, "Intravascular papillary endothelial hyperplasia of the mouth : report of six cases and literature review", Oral Dis, 5(2), pp.175~178 (1999)
- Akdur NC, "Intravascular papillary endothelial hyperplasia : histomorphological and immunohistochemical features", Diagn Pathol, 8, pp.167~ (2013)
- Shin SJ, "Hemangiomas and angiosarcomas of the breast : diagnostic utility of cell cycle markers with emphasis on Ki-67", Arch Pathol Lab Med, 131(4), pp.538~544 (2007)
- Güvenç MG, "Intravascular papillary endothelial hyperplasia(Masson lesion)of the hypopharynx and larynx", Ear Nose Throat J, 87(12), pp.700~701 (2008)
- Hashimoto H, "Intravascular papillary endothelial hyperplasia. A clinicopathologic study of 91 cases", Am J Dermatopathol, 5(6), pp.539~546 (1983)
- Kuo T, "Masson’s"vegetant intravascular hemangioendothelioma : "a lesion often mistaken for angiosarcoma : study of seventeen cases located in the skin and soft tissues", Cancer, 38(3), pp.1227~1236 (1976)
- Clearkin KP, "Intravascular papillary endothelial hyperplasia", Arch Pathol Lab Med, 100(8), pp.441~444 (1976)
- Salyer WR, "Intravascular angiomatosis : development and distinction from angiosarcoma", Cancer, 36(3), pp.995~1001 (1975)
- Kreutner A Jr, "Intravascular papillary endothelial hyperplasia : light and electron microscopic observations of a case", Cancer, 42(5), pp.2304~2310 (1978)
- Eguchi T, "Intravascular papillary endothelial hyperplasia in the mandible : a case report", J Int Med Res, 48(11), pp.300060520972900~ (2020)
