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비만환아에서 복약기간에 따른 비만탕의 치료효과 비교연구

Comparisons of Effects of Biman-tang according to Administration Period in Childhood Obesity

이진수|박재우|이훈|박히준|김희만|김호철|허광욱|임영권|민서림
대한한방소아과학회 (The Association of Pediatrics of Korean Medicine)|2013.11|대한한방소아과학회지 (The Journal of Pediatrics of Korean Medicine)|제27권 제4호|pp. 57-67

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참고문헌

키워드

ObesityOverweightHerbal medicineKorean traditional medicineChildren and adolescence
주제분류한의학

초록

Objectives The purpose of this study is to investigate the safety and effect of Biman-tang (BMT) on two different administration periods in the treatment of childhood overweight and obesity. Methods In retrospective study, 39 overweight and obese (85th percentile ≤ Body Mass Index (BMI)) children were treated with BMT from January 2006 to April 2013 at Korean Medical Clinic in Suwon, Korea. The primary outcomes were the changes in BMI and Obesity Index (OI) from baseline to the treatment groups. Secondary outcomes included the changes in height, weight and safety of the medicine. Comparisons of BMI, OI, height and weight between the short-period (SP) treatment group and the long-period (LP) treatment group were done by using ANCOVA. Results The change of the mean of BMI (-0.5 ± 0.6 kg/m2 vs -1.4 ± 0.8 kg/m2, respectively; p=0.003) and OI (-3.6 ± 3.9% vs -9.7 ± 4.7%, respectively; p<0.001) showed significant reduction both in SP (n=16) and LP treatment group (n=23). The mean height showed no significant difference in both groups. The mean weight of LP treatment group showed significant reduction compared to SP treatment group (-0.2 ± 1.3 kg vs -1.6 ± 1.6 kg, respectively; p=0.006). Most of the children were compliant to the medication and no serious adverse events were found in two groups. Conclusions These findings emphasize that BMT is effective in the treatment of childhood obesity and it requires at least 45 days of treatment for the best result.

Abstract

Objectives The purpose of this study is to investigate the safety and effect of Biman-tang (BMT) on two different administration periods in the treatment of childhood overweight and obesity. Methods In retrospective study, 39 overweight and obese (85th percentile ≤ Body Mass Index (BMI)) children were treated with BMT from January 2006 to April 2013 at Korean Medical Clinic in Suwon, Korea. The primary outcomes were the changes in BMI and Obesity Index (OI) from baseline to the treatment groups. Secondary outcomes included the changes in height, weight and safety of the medicine. Comparisons of BMI, OI, height and weight between the short-period (SP) treatment group and the long-period (LP) treatment group were done by using ANCOVA. Results The change of the mean of BMI (-0.5 ± 0.6 kg/m2 vs -1.4 ± 0.8 kg/m2, respectively; p=0.003) and OI (-3.6 ± 3.9% vs -9.7 ± 4.7%, respectively; p<0.001) showed significant reduction both in SP (n=16) and LP treatment group (n=23). The mean height showed no significant difference in both groups. The mean weight of LP treatment group showed significant reduction compared to SP treatment group (-0.2 ± 1.3 kg vs -1.6 ± 1.6 kg, respectively; p=0.006). Most of the children were compliant to the medication and no serious adverse events were found in two groups. Conclusions These findings emphasize that BMT is effective in the treatment of childhood obesity and it requires at least 45 days of treatment for the best result.

참고문헌 (43)

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