성장을 주소로 한방병원에 내원한 환아의 한의치료 효과: Deep Learning 기반 골연령 판독 프로그램을 활용한 증례보고
Effect of Korean Medicine Treatment on Children Who Visited Korean Medicine Hospital for Growth: A Case Report Using Deep Learning-Based Bone Age Program
0
조회
0
다운로드
1
인용
0
참고문헌
키워드
초록
Objectives We aimed to compare the bone age (BA) estimation by a deep learning-based program and by a specialist in pediatrics of Korean medicine using the Tanner-Whitehouse 3 (TW3) technique for the cases of children who visited a Korean medicine hospital for growth, and to report the effect of Korean medicine treatment. Methods For three children who visited the Korean medicine hospital for growth, BA estimation by the deep learning program and by the specialist in pediatrics of Korean medicine using the TW3 technique was compared, and the time required for estimation was investigated. The change of height, BA, and predicted adult height (PAH) using deep learning program after Korean medicine treatment was observed. Results BA estimation of the left hand bone X-ray by the specialist using the TW3 technique showed a difference of -0.03 to +0.15 years from the estimation by the deep learning program. The mean estimation time was 5 minutes and 49 seconds per one for the specialist and 48 seconds for the deep learning program. During the treatment period, the height percentile and PAH estimated by deep learning program were increased after Korean medicine treatment compared to baseline while acceleration of BA was suppressed compared to chronological age. Conclusions BA estimation using the deep learning program and the TW3 technique showed a difference of less than 0.15 years, and in three cases of patients with growth as the chief complaint, Korean medicine treatment increased height percentile and PAH without accelerating BA maturation.
Abstract
Objectives We aimed to compare the bone age (BA) estimation by a deep learning-based program and by a specialist in pediatrics of Korean medicine using the Tanner-Whitehouse 3 (TW3) technique for the cases of children who visited a Korean medicine hospital for growth, and to report the effect of Korean medicine treatment. Methods For three children who visited the Korean medicine hospital for growth, BA estimation by the deep learning program and by the specialist in pediatrics of Korean medicine using the TW3 technique was compared, and the time required for estimation was investigated. The change of height, BA, and predicted adult height (PAH) using deep learning program after Korean medicine treatment was observed. Results BA estimation of the left hand bone X-ray by the specialist using the TW3 technique showed a difference of -0.03 to +0.15 years from the estimation by the deep learning program. The mean estimation time was 5 minutes and 49 seconds per one for the specialist and 48 seconds for the deep learning program. During the treatment period, the height percentile and PAH estimated by deep learning program were increased after Korean medicine treatment compared to baseline while acceleration of BA was suppressed compared to chronological age. Conclusions BA estimation using the deep learning program and the TW3 technique showed a difference of less than 0.15 years, and in three cases of patients with growth as the chief complaint, Korean medicine treatment increased height percentile and PAH without accelerating BA maturation.
참고문헌 (27)
- Ahn HS, "Hong Changui pediatrics", pp.2~1204 (2016), Mirae N
- 최선희, "성장 치료를 목적으로 한방병원에 내원한 환아에 대한 임상적 고찰", 대한한방소아과학회지, 32(4), pp.51~62 (2018), 대한한방소아과학회[DOI]
- "Korean medicine utillization and herbal medicine consumption survey" (2021)[URL]
- Tanner JM, "Assessment of skeletal maturity and prediction of adult height (TW3 method)", pp.21~30 (2005), Panmoon Book
- Greulich WW, "Radiographic atlas of skeletal development of the hand and wrist", pp.50~250 (1959), Stanford University Press
- Canavese F, "Skeletal age assessment from elbow radiographs", Review of the literature. Chir Organi Mov, 92, pp.1~6 (2008)
- Pose Lepe G, "Correlation in radiological bone age determination using the Greulich and Pyle method versus automated evaluation using BoneXpert software", Rev Chil Pediatr, 89(5), pp.606~611 (2018)
- Pan I, "Rethinking Greulich and Pyle : a deep learning approach to pediatric bone age assessment using pediatric trauma hand radiographs", Radiol Artif Intell, 2(4), pp.e190198~ (2020)
- Kim JR, "Computerized bone age estimation using deep learning based program : evaluation of the accuracy and efficiency", AJR Am J Roentgenol, 209(6), pp.1374~1380 (2017)
- 한지은, "소아 성장에 대한 한의학 치료: 국내 임상연구에 대한 문헌적 고찰", 대한한방소아과학회지, 35(1), pp.18~29 (2021), 대한한방소아과학회
- Ranke MB, "Growth hormone-past, present and future", Nat Rev Endocrinol, 14(5), pp.285~300 (2018)
- 임정태, "Hypothesis Proposal about Predictive Factors and Optimal Age for Response to Herbal Medicine Treatment for Height Gain in Children: a Retrospective Review", 대한한의학회지, 39(4), pp.16~29 (2018), 대한한의학회[DOI]
- 신충호, "성장호르몬 치료의 최신 지견", Clinical and Experimental Pediatrics, 49(7), pp.703~709 (2006), 대한소아청소년과학회
- 이희철, "소아에서 성장호르몬 치료 중 발생한 특발유두부종과 결합된 가성유두부종", 대한안과학회지, 61(12), pp.1548~1552 (2020), 대한안과학회
- Kim YJ, "Integrative traditional Korean medicine treatment for children with idiopathic short stature : a STROBE-compliant case series", Medicine(Baltimore), 101(28), pp.e29754~ (2022)
- 이유진, "소아 성장을 위한 한약 투여에 대한 임상적 연구", 대한한방소아과학회지, 25(1), pp.49~62 (2011), 대한한방소아과학회
- 김지은, "소아 성장을 위한 한약 투여에 대한 후향적 연구", 대한한방소아과학회지, 30(4), pp.87~98 (2016), 대한한방소아과학회
- Korea Center for Disease Control and Prevention, "2017 Korean children and adolescents growth standard (commentary for the development of 2017 growth charts)", Division of Chronic Disease Surveillance, 25~35 (2017)
- Wang JL, "Effect study of adjusting dual power of negative and positive invigorating spleen and kidney therapy on 40 cases of insulin growth factor, height and weight of idiopathic short stature", Smart Healthc, 6(12), pp.101~102 (2020)
- Feng B, "Research on three traditional Chinese medicine treatment methods of children with idiopathic short stature", Nei Mongol J Tradit Chin Med, 33(29), pp.4~5 (2014)
- Xu QW, "Clinical Research on Promoting the Growth of Idiopathic Short Stature With Ginseng Turtle Feed Particles", pp.2015
- Sun FP, "Clinical observation on 20 cases of idiopathic short stature in preschool children treated with Buzhong Zhuzhang granules", J Pediatr Tradit Chin Med, 13(4), pp.57~60 (2017)
- Aram Jeong, "Efficacy and safety of fermented oyster extract for height of children with short stature: a randomized placebo-controlled trial", Integrative Medicine Research, 10(2), pp.1~6 (2021), 한국한의학연구원[DOI]
- Kim SC, "Herbal prescription", pp.276~549 (1990), Yeong Rim Sa Publishing Co
- Yang KS, "Combination and application of herbal medicine for prescription composition", pp.25~103 (1993), Korea Bio Medical Science Institute
- 강경화, "마황천오 약침액이 3T3-L1 지방세포 분화 및 유전자발현에 미치는 영향", Korean Journal of Acupuncture, 31(4), pp.168~178 (2014), 경락경혈학회[DOI]
- Korean Society of Chuna Manual Medicine for Spine and Nerves, "Chuna manual medicine", pp.14~35 (2017), Korean Society of Chuna Manual Medicine for Spine & Nerves