의도성 중독의 변화 양상: 15년간의 후향적 단일병원 연구
Trends of Intentional Poisoning: A Retrospective Single Center Study During 15 Years
1
조회
0
다운로드
3
인용
0
참고문헌
키워드
초록
Purpose: Intentional poisoning is a major public health issue in many parts of the world. This study was conducted to provide details regarding the epidemiology of intentional poisoning in a metropolitan emergency department and to identify the changing patterns and epidemiology of poisoning. Methods: A retrospective study was conducted to evaluate intentional poisoning of patients who visited the emergency department in a tertiary teaching hospital between 2001 and 2015. All intentional poisoning-related emergency department visits over three five year periods (2001-2005 (P1), 2006-2010 (P2) and 2011-2015 (P3)) were reviewed to investigate trends in intentional poisoning patients. Information regarding patient sex, age, time from episode to admission, psychiatric history, type of intoxicants, alcohol co-ingestion, gastric lavage, charcoal administration, any previous suicide attempts, need for hospitalization and death before discharge was reviewed. Results: A total of 1269 patients were enrolled in this study. The number of patients admitted during each period was P1=515, P2=439 and P3=315. Comparison of the three groups revealed significant differences according to age (p<0.001), psychiatric history (p<0.001), alcohol co-ingestion (p=0.013), gastric lavage (p<0.001), charcoal administration (p<0.001), need for hospitalization (p=0.044), repeated attempt (p<0.001) and type of intoxicants (p<0.001). Conclusion: The average age of intentional poisoning patients has increased. While the use of sedatives and multiple drugs increased, the use of pesticides and the antihistamine decreased.
Abstract
Purpose: Intentional poisoning is a major public health issue in many parts of the world. This study was conducted to provide details regarding the epidemiology of intentional poisoning in a metropolitan emergency department and to identify the changing patterns and epidemiology of poisoning. Methods: A retrospective study was conducted to evaluate intentional poisoning of patients who visited the emergency department in a tertiary teaching hospital between 2001 and 2015. All intentional poisoning-related emergency department visits over three five year periods (2001-2005 (P1), 2006-2010 (P2) and 2011-2015 (P3)) were reviewed to investigate trends in intentional poisoning patients. Information regarding patient sex, age, time from episode to admission, psychiatric history, type of intoxicants, alcohol co-ingestion, gastric lavage, charcoal administration, any previous suicide attempts, need for hospitalization and death before discharge was reviewed. Results: A total of 1269 patients were enrolled in this study. The number of patients admitted during each period was P1=515, P2=439 and P3=315. Comparison of the three groups revealed significant differences according to age (p<0.001), psychiatric history (p<0.001), alcohol co-ingestion (p=0.013), gastric lavage (p<0.001), charcoal administration (p<0.001), need for hospitalization (p=0.044), repeated attempt (p<0.001) and type of intoxicants (p<0.001). Conclusion: The average age of intentional poisoning patients has increased. While the use of sedatives and multiple drugs increased, the use of pesticides and the antihistamine decreased.
참고문헌 (22)
- "OECD Health Data 2013"[URL]
- "Annual report on the cause of death statics" (2013)[URL]
- Christiansen E, "Risk of repetition of suicide attempt, suicide or all deaths after an episode of attempted suicide: a register-based survival analysis", Aust N Z J Psychiatry, 41, pp.257~265 (2007)
- Hawton K, "Suicide following deliberate self-harm: long-term follow-up of patients who presented to a general hospital", Br J Psychiatry, 182, pp.537~542 (2003)
- Cook R, "Self-poisoning: current trends and practice in a U.K. teaching hospital", Clin Med, 8, pp.37~40 (2008)
- Prescott K, "Detailed analyses of self-poisoning episodes presenting to a large regional teaching hospital in the UK", Br J Clin Pharmacol, 68, pp.260~268 (2009)
- Hendrix L, "Deliberate self-poisoning: characteristics of patients and impact on the emergency department of a large university hospital", Emerg Med J, 30, pp.e9~ (2013)
- Viertel A, "Cases of acute poisoning admitted to a medical intensive care unit", Dtsch Med Wochenschr, 126, pp.1159~1163 (2001)
- Schwake L, "Adverse drug reactions and deliberate self poisoning as cause of admission to the intensive care unit: a 1-year prospective observational cohort study", Intensive Care Med, 35, pp.266~274 (2009)
- Finkelstein Y, "Risk of Suicide Following Deliberate Self-poisoning", JAMA Psychiatry, 72, pp.570~575 (2015)
- Bronstein AC, "2011 Annual report of the American Association of Poison Control Centers’ National Poison Data System (NPDS): 29th Annual Report", Clin Toxicol (Phila), 50, pp.911~1164 (2012)
- "Index.go.kr"[URL]
- Muhlberg W, "Acute poisoning in old and very old patients: a longitudinal retrospective study of 5,883 patients in a toxicological intensive care unit", Z Gerontol Geriatr, 38, pp.182~189 (2005)
- 이운정, "노인 급성 약물 중독 환자의 임상적 고찰", Annals of geriatric medicine and research, 13(1), pp.24~30 (2009), 대한노인병학회
- Buckley NA, "An analysis of age and gender influences on the relative risk for suicide and psychotropic drug self-poisoning", Acta Psychiatr Scand, 93, pp.168~171 (1996)
- Rahman A, "Deliberate self-poisoning presenting to an emergency medicine network in South-East melbourne: a descriptive study", Emerg Med Int, 2014, pp.1~7 (2014)
- Ponampalam R, "Demographics of toxic exposures presenting to three public hospital emergency departments in Singapore 2001-2003", Int J Emerg Med, 2, pp.25~31 (2009)
- Townsend E, "Substances used in deliberate self-poisoning 1985-1997:trends and associations with age, gender, repetition and suicide intent", Soc Psychiatry Psychiatr Epidemiol, 36, pp.228~234 (2001)
- Ok TG, "The clinical investigation of drug intoxication in the North-Youngseo district of Kangwon province", J Korean Soc Clin Toxicol, 2, pp.83~89 (2004)
- Bhaskaran J, "Population trends in substances used in deliberate self-poisoning leading to intensive care unit admissions from 2000 to 2010", J Clin Psychiatry, 76, pp.1583~1589 (2010)
- Ae Jin Sung, "Multicenter Survey of Intoxication Cases in Korean Emergency Departments:2nd Annual Report, 2009", J Korean Soc Clin Toxicol, 10, pp.22~32 (2012)
- Albertson TE, "Gastrointestinal decontamination in the acutely poisoned patient", Int J Emerg Med, 4, pp.65~ (2011)
