체육영재 아동의 VDR FokⅠ 유전자 다형성에 따른 체격 및 체력 비교
Comparison of physique and physical fitness factors by Vitamin D Receptor FokⅠ polymorphism in athletic gifted children
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[목적] 본 연구의 목적은 체육영재아동의 비타민D 수용체(VDR) FokІ 유전자 다형성에 따라 운동 수행력에 영향을 미치는 체격과 체력의 차이를 분석하는 데 있었다. [방법] 남아 82명(9.1±0.9세)과 여아 55명(9.3±0.9세) 137명이 본 연구에 참여하였고, 이들의 FokI VDR 다형성이 분석되었다. 기본 체력변인(농구공 던지기, 하프 스쿼트 점프, 제자리 멀리 뛰기, 15m 옹복달리기, 50m 달리기, 악력, 사이드 스텝, 체전굴, 윗몸 일으키기)과 체격 변인들은 One-way ANOVA 분석 후 유의한 차이가 있을 경우 사후분석으로 bonferroni test를 이용하여 분석하였다. [결과] 남녀 아동 모두 VDR FokІ 유전자형에 따른 체력 및 체격 변인 사이의 연관성은 발견되지 않았다. 하지만 Hardy-Weinberg 평형 결과에서 유의한 차이가 나타났다(χ2= 6.516, df=2, p=.038). [결론] 비록 VDR FokІ 유전자다형성에 따른 체력변인에서의 유의한 차이는 나타나지 않았지만 H-W 평형검사에서 유의한 차이가 나타났다. 이러한 점에서 VDR FokІ 유전자가 체력을 예측할 수 있는 가능성을 배제하기는 어렵다고 판단된다. 따라서 체력을 예측할 수 있는 VDR FokІ 유전자의 가능성을 확인하기 위해서는 일반 아동을 대상으로 한 추가적인 연구가 진행되어야 할 것이다.
Abstract
[Purpose] The purpose of this study is to examine the differences in physique and physical fitness factors affecting exercise performance according to the vitamin D receptor (VDR) FokI gene polymorphism in athletic gifted children. [Methods] FokI VDR polymorphisms were genotyped in 82 boys (9.1±0.9 years) and 55 girls (9.3±0.9 years). Basic physical fitness (basketball throw, half-squat jump, standing long jump, 15m pacer, 50m run, handgrip strength, side-step, trunk forward flexion, sit-up) and physique were measured and analyzed using one-way ANOVA with bonferroni’s correction. [Results] No association was found between the VDR FokI genotypes and all the physical fitness variables as well as physique variables in boys and girl. However, Hardy-Weinberg equilibrium results for VDR polymorphism distribution showed significant differences (χ2= 6.516, df=2, p=.038). [Conclusion] Although there was no significant difference in the fitness variables according to the VDR Fok1 genotype, it was difficult to exclude the potential for predicting fitness in that the H-W equilibrium test showed a significant difference. Therefore, in order to confirm the true potential of the VDR Fok1 gene to predict physical fitness, it is considered that additional studies on general children should be conducted.
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