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유기농 산양유 사료에 산삼배양근 첨가가 산양유와 혈액 내 진세노사이드 함량 및 조성에 미치는 영향

Effect of Supplementing Cultured Wild Ginseng Roots in the Diet of Organic Saanen Dairy Goats on Milk Composition and Ginsenoside Profiles in Blood and Milk

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초록

The aim of the present study was to determine the effect of dietary cultured wild ginseng root (CWGR) supplementation on goat milk composition and ginsenoside profiles. Sixteen Saanen dairy goats were allocated to two balanced groups based on lactation period, body weight (38.6±3.2 kg), and dairy milk yield (2.85±1.2 kg), and were kept in separate pens. Goats were fed a total mixed ration (TMR) feed (2.3 kg/d, dry matter basis) and 1.5 g of CWGR powder was supplemented in the experimental diet. The total feeding period was 3 weeks, and milk and blood samples were collected on the last three days of the experimental period. There was no effect of CWGR on daily milk yield and milk composition (fat, protein, lactose, and solid-not-fat). However, the CWGR-treatment group had significantly higher plasma IgG and protein contents than the control group (P<0.05). Significant amounts of ginsenosides were observed in the milk of the CWGR-treatment group, whereas ginsenosides were not detected in the milk of the control group. In conclusion, dietary CWGR was a useful regimen to produce functional goat milk enriched in ginsenosides.

Abstract

The aim of the present study was to determine the effect of dietary cultured wild ginseng root (CWGR) supplementation on goat milk composition and ginsenoside profiles. Sixteen Saanen dairy goats were allocated to two balanced groups based on lactation period, body weight (38.6±3.2 kg), and dairy milk yield (2.85±1.2 kg), and were kept in separate pens. Goats were fed a total mixed ration (TMR) feed (2.3 kg/d, dry matter basis) and 1.5 g of CWGR powder was supplemented in the experimental diet. The total feeding period was 3 weeks, and milk and blood samples were collected on the last three days of the experimental period. There was no effect of CWGR on daily milk yield and milk composition (fat, protein, lactose, and solid-not-fat). However, the CWGR-treatment group had significantly higher plasma IgG and protein contents than the control group (P<0.05). Significant amounts of ginsenosides were observed in the milk of the CWGR-treatment group, whereas ginsenosides were not detected in the milk of the control group. In conclusion, dietary CWGR was a useful regimen to produce functional goat milk enriched in ginsenosides.

참고문헌 (35)

  1. Akao, T., "Appearance of compound K, a major metabolite of ginsenoside Rb1 by intestinal bacteria, in rat plasma after oral administration- measurement of compound K by enzyme immunoassay", Biol. Pharm. Bull, 21, pp.245~249 (1998)
  2. 배귀석, "산삼배양액 이용에 관한 반추위 미생물 대사 연구", 한국동물자원과학회지, 45(6), pp.987~996 (2003), 한국동물자원과학회
  3. Benchaar, C., "Digestion, ruminal fermentation, ciliate protozoal populations, and milk production from dairy cows fed cinnamaldehyde, quebracho condensed tannin, or yucca schidigera saponin extracts", J. Dairy Sci, 91, pp.4765~4777 (2008)
  4. Bird, S. H., "The effects of defaunation of the rumen on the growth of cattle on low-protein high-energy diets", Br. J. Nutr, 40, pp.163~167 (1978)
  5. Chen, X., "Ginsenosides-induced nitric oxide-mediated relaxation of the rabbit corpus cavernosum", Br. J. Pharmacol, 115, pp.15~18 (1995)
  6. Concha, C., "The proliferative responses of cow stripping milk and blood lymphocytes to pokeweed mitogen and ginseng in vitro", Vet. Res, 27, pp.107~115 (1996)
  7. Demeyer, D. I., "Effect of defaunation on the metabolism of rumen micro-organisms", Br. J. Nutr, 42, pp.515~524 (1979)
  8. Endale, M., "Korean red ginseng saponin fraction rich in ginsenoside-Rb1, Rc and Rb2 attenuates the severity of mouse collagen-induced arthritis", Mediat. Inflamm, 2014, pp.14~ (2014)
  9. Francis, G., "The biological action of saponins in animal systems: a review", Br. J. Nutr, 88, pp.587~605 (2002)
  10. Fukuda, N., "Formation of monoclonal antibody against a major ginseng component, ginsenoside Rg1 and its characterization. Monoclonal antibody for a ginseng saponin", Cytotechnology, 34, pp.197~204 (2000)
  11. Hasegawa, H., "Main ginseng saponin metabolites formed by intestinal bacteria", Planta. Med, 62, pp.453~457 (1996)
  12. Hill, D. E., "Ascaris suum: stage-specific differences in lectin binding to the larval cuticle", Exp. Parasitol, 73, pp.376~383 (1991)
  13. Hu, S., "Ginseng-enhanced oxidative and phagocytic activities of polymorphonuclear leukocytes from bovine peripheral-blood and stripping milk", Veterinary Research, 26, pp.155~161 (1995)
  14. Hu, S., "Effect of subcutaneous injection of ginseng on cows with subclinical Staphylococcus aureus mastitis", J. Vet. Med. B. Infect. Dis. Vet. Public Health, 48, pp.519~528 (2001)
  15. Kim, J. S., "Screening of antioxidative components from red ginseng saponin", Korean J. Ginseng Sci, 20, pp.173~178 (1996)
  16. Lee, J. B., "Effect of ginseng saponins on the induction of β- glactosidase in yeast", J. Ginseng Res, 22, pp.310~315 (1998)
  17. Lee, S. J., "Induction of apoptosis by a novel intestinal metabolite of ginseng saponin via cytochrome c-mediated activation of caspase-3 protease", Biochem. Pharmacol, 60, pp.677~685 (2000)
  18. Lloyd, G., "Commercially-feasible micropropagation of mountain laurel, Kalmia latifolia, by use of shoot-tip culture", Combined Proceedings, International Plant Propagators’ Society, pp.421~427 (1980)
  19. Makkar, H. P. S, "Nutrional value and antinutritional components of whole and ethanol extracted Moringa oleifera leaves", Anim. Feed. Sci. Technol, 63, pp.211~228 (1996)
  20. Mancini, G., "Immunochemical quantitation of antigens by single radial immunodiffusion", Immunochemistry, 2, pp.235~254 (1965)
  21. Odani, T., "Studies on the absorption, distribution, excretion and metabolism of ginseng saponins. IV. Decomposition of ginsenoside-Rg1 and -Rb1 in the digestive tract of rats", Chem. Pharm. Bull. (Tokyo), 31, pp.3691~3697 (1983)
  22. Ohana, P., "Glycosylated triterpenoid saponin: a specific inhibitor of diguanylate cyclase from Acetobacter xylinum. Biological activity and distribution", Plant Cell Physiol, 39, pp.153~159 (1998)
  23. Owen, H. R., "An Examination and Correction of Plant-Tissue Culture Basal Medium Formulations", Plant Cell Tissue Organ Cult, 28, pp.147~150 (1992)
  24. Pell, A. N., "Tannins in Livestock and Human Nutrition", pp.121~126 (2000), ACIAR
  25. Quan, F. S,, "Ginseng and Salviae herbs play a role as immune activators and modulate immune responses during influenza virus infection", Vaccine, 25, pp.272~282 (2007)
  26. SAS, "SAS Procedures Guide, Version 8" (1999), SAS Institute Inc
  27. Shibata, S., "Effective components of ginseng", Tanpakushitsu Kakusan Koso, 12, pp.32~38 (1967)
  28. Song, X., "Ginseng stem-leaf saponins (GSLS) and mineral oil act synergistically to enhance the immune responses to vaccination against foot-and- mouth disease in mice", Vaccine, 27, pp.51~55 (2009)
  29. Strombom, J., "Studies on absorption and distribution of ginsenoside Rg-1 by whole-body autoradiography and chromatography", Acta. Pharm. Suec, 22, pp.113~122 (1985)
  30. Tanaka, O., "Chemical studies on the oriental plant drugs. XVI. The stereochemistry of protopanaxadiol, a genuine sapogenin of ginseng", Chem. Pharm. Bull. (Tokyo), 14, pp.1150~1156 (1966)
  31. VanEtten, H. D., "Two Classes of Plant Antibiotics: Phytoalexins versus “Phytoanticipins”", Plant Cell, 6, pp.1191~1192 (1994)
  32. Wang, Y., "Effect of condensed tannins upon the performance of lambs grazing Lotus corniculatus and lucerne (Medicago sativa)", J. Agric. Sci, 126, pp.87~98 (1996)
  33. Wang, Y., "Effects of Yucca schidigera extract on fermentation and degradation of steroidal saponins in the rumen simulation technique (RUSITEC)", Anim. Feed. Sci. Technol, 74, pp.143~153 (1998)
  34. Yang, Z. G., "Immunological adjuvant effect of ginsenoside Rh4 from the roots of Panax notoginseng on specific antibody and cellular response to ovalbumin in mice", Chem. Biodivers, 4, pp.232~240 (2007)
  35. Zhang, C., "Purification and characterization of ginsenoside-beta-glucosidase from ginseng", Chem. Pharm. Bull. (Tokyo), 49, pp.795~798 (2001)

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