Effects of Eco-friendly Multi-enzyme on Diarrhea and Immune Response of weaned Pigs
2
조회
0
다운로드
3
인용
0
참고문헌
키워드
초록
This study was designed to investigate the effects of multi-enzyme on diarrhea and immune responses of weaned pigs. A total 36 weaned pigs (5.92 ± 0.48 kg BW; 28 d old) were randomly allotted to 2 dietary treatments (3 pigs/pen, 6 replicates/ treatment) in a randomized complete block design. The dietary treatments were a typical diet based on corn and soybean meal (CON) and CON with 0.1% multi- enzyme (Multi; mixture of β-mannanase, xylanase, α-amylase, protease, β-glucanase, and pectinase). Pigs were fed their respective diets for 6 wk. Frequency of diarrhea, levels of packed cell volume (PCV), white blood cells (WBC), immunoglobulins, cortisol, tumor necrosis factor-α (TNF-α), transforming growth factor-β (TGF-β), and C-reactive protein (CRP) were measured. Multi group tended to decrease (p<0.1) diarrhea frequency than CON group during 2 wk after weaning. Lower values of PCV on d 3 (p<0.05) and d 7 (p<0.1) were found in Multi group compared with CON group. There were no significant differences on WBC number and immunoglobulin (Ig) M and A between Multi and CON groups. However, Multi group tended to increase (p<0.1) Ig G on d 7 than CON group. Moreover, Multi group showed modulated immune responses, indicated by decreased levels of cortisol (p<0.05) on d 7 and 14, TNF-α on d 3 (p<0.05) and d 7 (p<0.10), TGF-β on d 2 (p<0.05) and d 7 (p<0.10), and CRP (p<0.10) on d 3 and 7 after weaning compared with CON group. Consequently, inclusion of multi-enzyme in diets for weaned pigs improved gut health and modulated immune responses of weaned pigs.
Abstract
This study was designed to investigate the effects of multi-enzyme on diarrhea and immune responses of weaned pigs. A total 36 weaned pigs (5.92 ± 0.48 kg BW; 28 d old) were randomly allotted to 2 dietary treatments (3 pigs/pen, 6 replicates/ treatment) in a randomized complete block design. The dietary treatments were a typical diet based on corn and soybean meal (CON) and CON with 0.1% multi- enzyme (Multi; mixture of β-mannanase, xylanase, α-amylase, protease, β-glucanase, and pectinase). Pigs were fed their respective diets for 6 wk. Frequency of diarrhea, levels of packed cell volume (PCV), white blood cells (WBC), immunoglobulins, cortisol, tumor necrosis factor-α (TNF-α), transforming growth factor-β (TGF-β), and C-reactive protein (CRP) were measured. Multi group tended to decrease (p<0.1) diarrhea frequency than CON group during 2 wk after weaning. Lower values of PCV on d 3 (p<0.05) and d 7 (p<0.1) were found in Multi group compared with CON group. There were no significant differences on WBC number and immunoglobulin (Ig) M and A between Multi and CON groups. However, Multi group tended to increase (p<0.1) Ig G on d 7 than CON group. Moreover, Multi group showed modulated immune responses, indicated by decreased levels of cortisol (p<0.05) on d 7 and 14, TNF-α on d 3 (p<0.05) and d 7 (p<0.10), TGF-β on d 2 (p<0.05) and d 7 (p<0.10), and CRP (p<0.10) on d 3 and 7 after weaning compared with CON group. Consequently, inclusion of multi-enzyme in diets for weaned pigs improved gut health and modulated immune responses of weaned pigs.
참고문헌 (13)
- Barrera, M., "Iieal amino acid digestibility and performance of growing pigs fed wheat-based diets supplemented with xylanase", J. Anim. Sci., 82, pp.1997~2003 (2004)[DOI]
- Cho, J. H., "Effects of beta mannanase and xylanase supplementation in low energy density diets on performances, nutrient digestibility, blood profiles and meat quality in finishing pigs", Asian J. Anim. Vet. Adv., 8, pp.622~630 (2013)
- Choct, M., "Feed non-starch polysaccharides: Chemical structures and nutritional significance", Feed Milling Int, 191, pp.13~36 (1997)
- CVB, "Centraal Veevoeder Bureau. Veevoedertalel (Feeding value of feed ingredients);Centraal Veevoeder Bureau, Runderweg 6", ~ (1998)
- Protein sources for the animal feed industry, "FAO", Food and Agriculture Organization of the United Nations, ~ (2004)
- 강주원, "Effects of dietary enzyme cocktail on diarrhea and immune responses of weaned pigs", Korean Journal of Agricultural Science, 44(4), pp.525~530 (2017), 농업과학연구소[DOI]
- 김윤강, "Effects of dietary enzyme cocktail on growth performance, intestinal morphology, and nutrient digestibility of weaned pigs", Korean Journal of Agricultural Science, 44(4), pp.513~518 (2017), 농업과학연구소[DOI]
- Moeser, A. J., "Stress signaling pathways activated by weaning mediate intestinal dysfunction in the pig", Am. J. Physiol.-Gastroint. Liver Physiol., 292, pp.G173~G181 (2007)[DOI]
- Olukosi, O. A., "Supplementation of carbohydrases or phytase individually or in combination to diets for weanling and growing-finishing pigs", J. Anim. Sci., 85, pp.1702~1711 (2007)[DOI]
- Pare, J., "Effect of birthweight, total protein, serum IgG and packed cell volume on risk of neonatal diarrhea in calves on two California dairies", Can. J. Vet. Res., 57, pp.241~246 (1993)
- 박상우, "Nutrition and feed approach according to pig physiology", Korean Journal of Agricultural Science, 43(5), pp.750~760 (2016), 농업과학연구소[DOI]
- Pierce, K. M., "Performance of weanling pigs offered low or high lactose diets supplemented with avilamycin or inulin", Anim. Sci., 80, pp.313~318 (2005)
- 송민호, "Value of spray-dried egg in pig nursery diets", Korean Journal of Agricultural Science, 42(3), pp.207~213 (2015), 농업과학연구소