글리콜릭산 필링 후 확정세포배양액4로 제조한 화장품의 안면피부 미용효과
The Facial Skin Care Effects of the Cosmetics Which were Manufactured with Defined Cell Culture Medium 4 after Glycolic Acid Peeling
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This study was carried out to evaluate the efficacy of cosmetics manufactured with retinol, hyaluronic acidand defined cell culture media 4 (DCCM4) on facial skin care. All testing cosmetics were raised to hyaluronicacid, β-glucan, by 0.2% in the same addition. Also we prepared three kinds of testing cosmetics. Distilledwater was used as solvent of ingredients in hyaluronic acid testing cosmetics, retinyl palmitate were addedto hyaluronic acid testing cosmetics to 10,000 IU/g for retinol testing cosmetics, and DCCM4 was usedas solvent of ingredient in DCCM4 testing cosmetics. To achieve evaluation of efficacy, 30% glycolic acidpeeling was applied to facial skin of 32 study participants once a week during 4 weeks. By home care, theskin conditions were measured for the analysis of wrinkle, pigmentation, moisture and skin tone before andafter treatment after applying it 84 times twice a day for 6 weeks. In the change of facial skin between 32study participants, the moisture increased, but no significant difference among study group. For the wrinkle,DCCM4 was in great decrease below and around their eyes, which there was a significant difference (p<.01). For the pigmentation by polarized light, DCCM4 was in great decrease on their nose and cheeks, below andaround their eyes, which there was a significant difference (p<.05, p<.01, and p<.001). For the pigmentationby ultraviolet light, DCCM4 was in great decrease on their forehead and cheeks, below and around theireyes, which there was a significant difference (p<.05, p<.01, and p<.001). For the skin tone, DCCM4 was ingreat increase on their forehead, nose and cheeks, below their eyes more than retinol and HA, which therewas a significant difference (p<.01). As a consequence, cosmetics manufactured with DCCM4 can be usedfor improving skin aging, and it is expected to carry out more systematic and effective studies in the future.
Abstract
This study was carried out to evaluate the efficacy of cosmetics manufactured with retinol, hyaluronic acidand defined cell culture media 4 (DCCM4) on facial skin care. All testing cosmetics were raised to hyaluronicacid, β-glucan, by 0.2% in the same addition. Also we prepared three kinds of testing cosmetics. Distilledwater was used as solvent of ingredients in hyaluronic acid testing cosmetics, retinyl palmitate were addedto hyaluronic acid testing cosmetics to 10,000 IU/g for retinol testing cosmetics, and DCCM4 was usedas solvent of ingredient in DCCM4 testing cosmetics. To achieve evaluation of efficacy, 30% glycolic acidpeeling was applied to facial skin of 32 study participants once a week during 4 weeks. By home care, theskin conditions were measured for the analysis of wrinkle, pigmentation, moisture and skin tone before andafter treatment after applying it 84 times twice a day for 6 weeks. In the change of facial skin between 32study participants, the moisture increased, but no significant difference among study group. For the wrinkle,DCCM4 was in great decrease below and around their eyes, which there was a significant difference (p<.01). For the pigmentation by polarized light, DCCM4 was in great decrease on their nose and cheeks, below andaround their eyes, which there was a significant difference (p<.05, p<.01, and p<.001). For the pigmentationby ultraviolet light, DCCM4 was in great decrease on their forehead and cheeks, below and around theireyes, which there was a significant difference (p<.05, p<.01, and p<.001). For the skin tone, DCCM4 was ingreat increase on their forehead, nose and cheeks, below their eyes more than retinol and HA, which therewas a significant difference (p<.01). As a consequence, cosmetics manufactured with DCCM4 can be usedfor improving skin aging, and it is expected to carry out more systematic and effective studies in the future.
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