국내산과 중국산 삼지구엽초의 생리활성 비교

Abstract

This study was carried out to compare the biological activities of Epimedium koreanum Nakai grown wild in Korea and China. The antioxidative effect of E. koeranum Nakai-extracts grown wild in Gangwondo was 78%, which was higher than that in China as 71%. The inhibition ratio of growing cancer cells was estimated as 89, 91 and 86% for human liver, lung and breast cancer cell lines, respectively in adding 0.1g/ℓ of ethanol extracts of E. koreanum grown in Korea. The hepatoprotecive effect and Angiotensin Converting Enzyme (ACE) inhibiting effect of Korean one were also observed as 124 adn 87%, respectively, which were also higher than hose produced in China. There was not much difference between Korean and Chinese one in inhibiting α-glucosidase activities in all ranges of supplement. It proved that most effective extraction solvent was mixed type as water and ethanol (1:1, v/v) to have higher biological activities from both Korean and Chinese ones.