A Case of Acute Necrotizing Fasciitis Following Internal Jugular Vein Thrombophlebitis: Lemierre's Syndrome
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Lemierre’s syndrome is caused by preexisting oropharyngeal infection and characterized by internal jugular vein (IJV) thrombophlebitis. Frequently, this syndrome involves metastatic infection in areas such as the peritoneum, muscles, and spleen. The most common etiologic organism is Fusobacterium necrophorum. In this case, a masticatory space abscess that originated from a tooth caused the IJV thrombophlebitis. The patient had preexisting hypertension, diabetes mellitus, hyperlipidemia, and Parkinson’s disease. Blood culture revealed Streptococcus sanguinis, and the patient received antibiotics that were highly sensitive to mentioned bacterium; additionally, an anticoagulant was used. With the widespread use of antibiotics, Lemierre’s syndrome has become uncommon, and related mortality rates have noticeably decreased. This has led the public to forget about the disease, but it can still be potentially fatal without early diagnosis and appropriate antibiotic treatment.
Abstract
Lemierre’s syndrome is caused by preexisting oropharyngeal infection and characterized by internal jugular vein (IJV) thrombophlebitis. Frequently, this syndrome involves metastatic infection in areas such as the peritoneum, muscles, and spleen. The most common etiologic organism is Fusobacterium necrophorum. In this case, a masticatory space abscess that originated from a tooth caused the IJV thrombophlebitis. The patient had preexisting hypertension, diabetes mellitus, hyperlipidemia, and Parkinson’s disease. Blood culture revealed Streptococcus sanguinis, and the patient received antibiotics that were highly sensitive to mentioned bacterium; additionally, an anticoagulant was used. With the widespread use of antibiotics, Lemierre’s syndrome has become uncommon, and related mortality rates have noticeably decreased. This has led the public to forget about the disease, but it can still be potentially fatal without early diagnosis and appropriate antibiotic treatment.
참고문헌 (12)
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