소아에서 플루오린 함유 치약 섭취 후 발생한 출혈 위염 1례
A case of hemorrhagic gastritis caused by accidental ingestion of fluoride-containing toothpaste
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Fluoride is one of the most reactive elements in nature, and commonly used in toothpaste since it helps to prevent cavities. Despite this advantage, excessive ingestion of fluoride can cause acute toxicity and gastric disturbance from hydrofluoric acid that was formed in the stomach. We report a case of previously healthy, 41-month-old girl who visited the emergency department with persistent abdominal pain and hematemesis after ingestion of fluoride-containing toothpaste. Though the ingested dose of fluoride was below the toxic dose, serious symptoms developed. We performed esophagogastroduodenoscopy, and confirmed a hemorrhagic gastritis caused by hydrofluoric acid. The girl was uneventfully discharged on day 3 after receiving conservative care. When managing children who ingested fluoride-containing toothpaste, physicians need to consider their symptoms, not the ingested amount. In addition, parents should be cautious when their children use fluoridecontaining toothpaste.
Abstract
Fluoride is one of the most reactive elements in nature, and commonly used in toothpaste since it helps to prevent cavities. Despite this advantage, excessive ingestion of fluoride can cause acute toxicity and gastric disturbance from hydrofluoric acid that was formed in the stomach. We report a case of previously healthy, 41-month-old girl who visited the emergency department with persistent abdominal pain and hematemesis after ingestion of fluoride-containing toothpaste. Though the ingested dose of fluoride was below the toxic dose, serious symptoms developed. We performed esophagogastroduodenoscopy, and confirmed a hemorrhagic gastritis caused by hydrofluoric acid. The girl was uneventfully discharged on day 3 after receiving conservative care. When managing children who ingested fluoride-containing toothpaste, physicians need to consider their symptoms, not the ingested amount. In addition, parents should be cautious when their children use fluoridecontaining toothpaste.
참고문헌 (14)
- Carey CM, "Focus on fluorides : update on the use of fluoride for the prevention of dental caries", J Evid Based Dent Pract, 14(Suppl), pp.95~102 (2014)
- Kaya S, "Fluorine: chemistry, analysis, function and effects", pp.173~178 (2015), The Royal Society of Chemistry
- Baez RJ, "Basic methods for assessing renal fluoride excretion in community prevention programmes for oral health", pp.7~8 (2014), World Health Organization
- Shulman JD, "Acute fluoride toxicity from ingesting home-use dental products in children, birth to 6 years of age", J Public Health Dent, 57, pp.150~158 (1997)
- Davies RM, "The rational use of fluoride toothpaste", Int J Dent Hyg, 1, pp.3~8 (2003)
- Whitford GM, "The metabolism and toxicity of fluoride", pp.112~136 (1996), Karger
- Bentley EM, "Fluoride ingestion from toothpaste by young children", Br Dent J, 186, pp.460~462 (1999)
- Ericsson Y, "Fluoride retained from mouthrinses and dentifrices in preschool children", Caries Res, 3, pp.290~299 (1969)
- Guha-Chowdhury N, "Total fluoride intake in children aged 3 to 4 years--a longitudinal study", J Dent Res, 75, pp.1451~1457 (1996)
- Akiniwa K, "Re-examination of acute toxicity of fluoride", Fluoride, 30, pp.89~104 (1997)
- Gummin DD, "2018 annual report of the American Association of Poison Control Centers’ National Poison Data System (NPDS): 36th annual report", Clin Toxicol (Phila), 57, pp.1220~1413 (2019)
- Bajraktarova-Valjakova E, "Hydrofluoric acid : burns and systemic toxicity, protective measures, immediate and hospital medical treatment", Open Access Maced J Med Sci, 6, pp.2257~2269 (2018)
- Buzalaf MA, "Fluoride and the oral environment", pp.20~36 (2011), Karger
- Blinkhorn A, "Handbook of pediatric dentistry", pp.63~78 (2013), Mosby Elsevier
