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A case of esophageal perforation caused by suicidal caffeine poisoning in a teenager

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초록

Spontaneous esophageal perforation (also known as Boerhaave syndrome) is associated with sudden increase in intra-esophageal pressure by vomiting, coughing or straining at stool. This case describes a 13-year-old girl who developed the perforation after consuming 270 mg/kg of caffeine tablets for a suicide attempt. Presumably, the perforation was caused primarily by caffeine- induced severe vomiting, and secondarily by caffeine-induced gastric acid secretion with smooth muscle relaxation and by the large amount of caffeine-induced sudden increase in intra-esophageal pressure.

Abstract

Spontaneous esophageal perforation (also known as Boerhaave syndrome) is associated with sudden increase in intra-esophageal pressure by vomiting, coughing or straining at stool. This case describes a 13-year-old girl who developed the perforation after consuming 270 mg/kg of caffeine tablets for a suicide attempt. Presumably, the perforation was caused primarily by caffeine- induced severe vomiting, and secondarily by caffeine-induced gastric acid secretion with smooth muscle relaxation and by the large amount of caffeine-induced sudden increase in intra-esophageal pressure.

참고문헌 (5)

  1. Rentea RM, "Neonatal and pediatric esophageal perforation", Semin Pediatr Surg, 26, pp.87~94 (2017)
  2. Guttman OR, "Drug-induced esophageal injury with an occult vascular ring", Paediatr Child Health, 16, pp.554~556 (2011)
  3. Boyce HW Jr, "Drug-induced esophageal damage : diseases of medical progress", Gastrointest Endosc, 47, pp.547~550 (1998)
  4. Szeremeta M, "Rare complications of fatal caffeine intoxication", Forensic Sci, 2, pp.144~154 (2022)
  5. Lieu MT, "Tension hydropneumothorax as the initial presentation of Boerhaave syndrome", Respir Med Case Rep, 25, pp.100~103 (2018)

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