조영제 증강 CT 검사 환자에서 eGFR 을 적용한 부작용 분석
Analysis of eGFR Calculator in Patients Undergoing Contrast Media Enhanced CT Examination
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초록
The purpose of this study was to investigate creatinine and estimated glomerular filtrationrate (eGFR) in patients with CT using eGFR, and to provide a baseline data to prevent contrastinduced nephropathy (CIN) To provide basic data. Patients who visited the hospital for CTexamination were injected with contrast medium and examined for side effects. Contrast mediuminjection rate, injection rate, adverse reations, type of contrast agent, sex, and creatinine were enteredinto eGFR. The study of side effects of contrast media was conducted with the consent of thepatients and the adverse effects following contrast injection were investigated according to the studyethics guidelines. Twenty-four patients with adverse drug reactions were included in the CT scan. Contrast medium was injected from a minimum of 80 ml to a maximum of 120 ml, and the injectionrate per second was from 1.7 ml·s-1 to 4.5 ml·s-1. Among the patients, creatinine was measuredvariously according to the patient. In regression analysis of creatinine according to eGFR,R2 showed a distribution of 0.747 and showed a linear relationship of inverse. We investigated retrospectivelythe creatinine and eGFR of patients with CT using eGFR to prevent side effects of contrastagents and provide basic data. In the case of adverse effects in the CT contrast agent, eGFRshowed an inverse linear relationship in regression analysis according to creatinine.
Abstract
The purpose of this study was to investigate creatinine and estimated glomerular filtrationrate (eGFR) in patients with CT using eGFR, and to provide a baseline data to prevent contrastinduced nephropathy (CIN) To provide basic data. Patients who visited the hospital for CTexamination were injected with contrast medium and examined for side effects. Contrast mediuminjection rate, injection rate, adverse reations, type of contrast agent, sex, and creatinine were enteredinto eGFR. The study of side effects of contrast media was conducted with the consent of thepatients and the adverse effects following contrast injection were investigated according to the studyethics guidelines. Twenty-four patients with adverse drug reactions were included in the CT scan. Contrast medium was injected from a minimum of 80 ml to a maximum of 120 ml, and the injectionrate per second was from 1.7 ml·s-1 to 4.5 ml·s-1. Among the patients, creatinine was measuredvariously according to the patient. In regression analysis of creatinine according to eGFR,R2 showed a distribution of 0.747 and showed a linear relationship of inverse. We investigated retrospectivelythe creatinine and eGFR of patients with CT using eGFR to prevent side effects of contrastagents and provide basic data. In the case of adverse effects in the CT contrast agent, eGFRshowed an inverse linear relationship in regression analysis according to creatinine.
참고문헌 (21)
- Cockcroft DW, "Prediction of creatinine clearance from serum creatinine", Nephron, 16(1), pp.31~41 (1976)
- Coresh J, "Prevalence of chronic kidney disease and decreased kidney function in the adult US population: Third National Health and Nutrition Examination Survey", Am. J. Kidney Dis, 41(1), pp.1~12 (2003)
- Giles PD, "Formula estimation of glomerular filtration rate: have we gone wrong?", BMJ, 334(7605), pp.1198~1200 (2007)
- Keith DS, "Longitudinal follow-up and outcomes among a population with chronic kidney disease in a large managed care organization", Arch. Intern. Med, 22(164), pp.659~663 (2004)
- 김은영, "심혈관 조영술 시행 환자의 조영제 사용 시 사구체여과율 변화에 영향을 미치는 인자들 평가", 한국임상약학회지, 22(2), pp.103~112 (2012), 한국임상약학회[DOI]
- 김윤희, "Cr51-EDTA GFR과 비교한 Cystatin C 근거 GFR 추정값 및Creatinine 근거 GFR 추정값의 정확도 및 정밀도 평가", Annals of Laboratory Medicine, 27(1), pp.34~39 (2007), 대한진단검사의학회
- Kopp AF, "Prevalence of acute reactions to iopromide : postmarketing surveillance study of 74, 717 patients", Acta Radiol, 49(8), pp.902~911 (2008)
- Le Bricon T, "Plasma cystatin C is superior to 24-h creatinine clearance and plasma creatinine for estimation of glomerular filtration rate 3 months after kidney transplantation", Clin. Chem, 46(8), pp.1206~1207 (2000)
- Levey AS, "A more accurate method to estimate glomerular filtration rate from serum creatinine: a new prediction equation", Ann. Intern. Med, 130(6), pp.461~470 (1999)
- Levey AS, "National Kidney Foundation practice guidelines for chronic kidney disease: evaluation, classification, and stratification", Ann. Intern. Med, 139(2), pp.137~147 (2003)
- Levey AS, "Using standardized serum creatinine values in the modification of diet in renal disease study equation for estimating glomerular filtration rate", Ann. Intern. Med, 145(4), pp.247~254 (2006)
- Levey AS, "A simplified equation to predict glomerular filtration from serum creatinine", J. Am. Soc. Nephrol, 11(15), pp.155A~ (2000)
- Lysaght MJ, "Maintenance dialysis population dynamics: current trends and long-term implications", J. Am. Soc. Nephrol, 13(Suppl 1), pp.S37~S40 (2002)
- McCullough PA, "Contrast-induced acute kidney injury", J. Am. Coll. Cardiol, 51(15), pp.1419~1428 (2008)
- Murray CJ, "The state of US health, 1990-2010 : burden of diseases, injuries, and risk factors", JAMA, 14(310), pp.591~608 (2013)
- National Kidney Foundation, "K", DOQI clinical practice guidelines for chronic kidney disease: evaluation, classification, and stratification, 2002, pp.39(2), S1~S266
- Newman DJ, "Serum cystatin C measured by automated immunoassay : a more sensitive marker of changes in GFR than serum creatinine", Kidney Int, 47(1), pp.312~318 (1995)
- Song YH, "Relation between microalbuminuria and estimated glomerular filtration rate by creatinine and cystatin C", J. Lab. Med. Qual. Assur, 30(2), pp.259~265 (2008)
- Stevens LA, "Assessing kidney function: measured and estimated glomerular filtration rate", N. Engl. J. Med, 354(23), pp.2473~2483 (2006)
- Vanholder R, "Chronic kidney disease as cause of cardiovascular morbidity and mortality", Nephrol. Dial. Transplant, 20(6), pp.1048~1056 (2005)
- Vogl TJ, "Safety of iobitridol in the general population and atrisk patients", Eur. Radiol, 16(6), pp.1288~1297 (2006)