알츠하이머병 환자에서의 골밀도 확인
The Survey of Prevalence of Osteoporosis in Alzheimer's Disease Patients
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연구목적: 알츠하이머병 환자에서의 골다공증 유병률에 대해서 알아보고자 한다. 연구방법: 알츠하이머병으로 진단받은 환자 중 2010년도에 골밀도 검사를 시행하였던 128예에서 연령별 골다공증의 유병률을 조사하여 대조군과 비교 분석하였다. 결 과: 대조군에서의 골다공증 유병률은 29.73%이었고 알츠하이머병 환자에서의 골다공증 유병률은 96.87%이었다. 알츠하이머병 환자에서의 골감소증 유병률은 3.12%, 골절의 유병률은 32.03 %로 나타났다. 결 론: 알츠하이머병 환자에서 골다공증의 유병률이 대조군에서의 유병률 보다 높다.
Abstract
Objectives: To evaluate the prevalence of osteoporosis in the Alzheimer's disease patients. Methods: One hundred and twenty eight patients with Alzheimer's disease were included in this study. The patients are diagnosed with Alzheimer's disease using Korean-Mini Mental Status Examination (K-MMSE) and checked bone mineral density using single-energy (SE) quantitative computed tomography (QCT) in 2010. To define abnormality in terms of QCT of the spine, a bone mineral density (BMD) spine below 80 mg/cm3 is indicative of osteoporosis and BMD between 80 and 120 mg/㎤ is indicative osteopenia. Results: The prevalence of osteoporosis in the control group is 29.73%. The prevalence of osteoporosis in the Alzheimer's disease patients is 96.87%. The prevalence of osteopenia in the Alzheimer's disease patients is 3.12%. The prevalence of severe osteoporosis fracture in the Alzheimer's disease patients is 32.03%. Conclusion: The prevalence of osteoporosis in Alzheimer's disease patients is higher than in the control group. [Korean Journal of Bone Metabolism, 18(2): 125-130, 2011
참고문헌 (17)
- 장선미, "골다공증 환자의 의료이용 양상", 대한내분비학회지, 25(4), pp.326~339 (2010), 대한내분비학회
- Ministry for Health Welfare and Family Affairs, Korea Centers for Disease Control and Prevention, "National centers for health statistics. The fourth Korea national health and nutrition examination survey (KNHANES IV-2)" (2008), Ministry for Health Welfare and Family Affairs, Korea Centers for Disease Control and Prevention
- 강혜영, "우리나라 노인여성의 골다공증성 척추골절로 인한 경제적 부담 추계", 예방의학회지, 41(5), pp.287~294 (2008), 대한예방의학회
- Ha YC, "An epidemiological study of osteoporosis in Ibansung-Meon, Jinju, by using quantitative ultrasound", Korean J Bone Metab, 12, pp.217~223 (2005)
- Shin CS, "Prevalence and risk factors of osteoporosis in Korea: A community-based cohort study with lumbar spine and hip bone mineral density", BONE, 47, pp.378~387, ELSEVIER SCIENCE INC
- Yang NP, "Estimated prevalence of osteoporosis from a Nationwide Health Insurance database in Taiwan", Health Policy, 75, pp.329~337 (2006)
- Buchner DM, "Falls and fractures in patients with Alzheimer-type dementia", JAMA, 257, pp.1492~1495 (1987)
- Weller I, "Hip fractures and Alzheimer's disease in elderly institutionalized Canadians", Ann Epidemiol, 14, pp.319~324 (2004)
- Ishii Y, "Joint proprioception in the elderly with and without hip fracture", J Orthop Trauma, 14, pp.542~545 (2000)
- Sato Y, "High prevalence of vitamin D deficiency and reduced bone mass in elderly women with Alzheimer's disease", Bone, 23, pp.555~557 (1998)
- Han C, "An adaptation of the Korean mini-mental state examination (K-MMSE) in elderly Koreans: Demographic influence and population-based norms (the AGE study)", ARCH GERONTOL GERIATR, 47, pp.302~310
- Na HR, "Korean version of the Baylor Profound Mental Status Examination: a brief staging measure for patients with severe Alzheimer's disease", Dement Geriatr Cogn Disord, 27, pp.69~75 (2009)
- Engelke K, "Clinical use of quantitative computed tomography and peripheral quantitative computed tomography in the management of osteoporosis in adults: the 2007 ISCD Official Positions", J Clin Densitom, 11, pp.123~162 (2008)
- Tysiewicz-Dudek M, "Alzheimer's disease and osteoporosis: common risk factors or one condition predisposing to the other", Ortop Traumatol Rehabil, 10, pp.315~323 (2008)
- Kose N, "The risk factors of fall and their correlation with balance, depression, cognitive impairment and mobility skills in elderly nursing home residents", Saudi Med J, 26, pp.978~981 (2005)
- Haasum Y, "Undertreatment of osteoporosis in persons with dementia? A population-based study", Osteoporos Int (2011)
- Borgstrom F, "Costs and quality of life associated with osteoporosis-related fractures in Sweden", Osteoporos Int, 17, pp.637~650 (2006)