Changes of Paraspinal Muscles in Postmenopausal Osteoporotic Spinal Compression Fractures:Magnetic Resonance Imaging Study
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Background: To investigate the changes of cross sectional area (CSA) in paraspinal mus-cles upon magnetic resonance imaging (MRI) and bone mineral density (BMD) in post-menopausal osteoporotic spinal compression fractures. Methods: We reviewed 81 post-menopausal women with osteoporosis, who had underwent MRI examination. The pa-tients were divided into 51 patients who had osteoporotic spinal compression fractures (group I), and 30 patients who without fractures (group II). Group I were subdivided into IA and IB, based on whether they were younger (IA) of older (IB) than 70 years of age. We additionally measured body mass index and BMD. The CSA of multifidus, erector spinae,paraspinal muscles, psoas major (PT), and intervertebral (IV) discs were measured. The degree of fatty atrophy was estimated using three grades. Results: The BMD and T-score of group I were significantly lower than those of group II. The CSA of erector spinae, para-spinal muscles, and PT in the group I was significantly smaller than that of group II. The CSA of paraspinal muscles in group IB were significantly smaller than those of group IA. The CSA of erector spinae, mutifidus, and PT in group IB were smaller than those of group IA, but the difference was not statistically significant. Group 1 exhibited greater fat infil-tration in the paraspinal muscle than group II. Conclusions: Postmenopausal osteopo-rotic spinal compression fracture is associated with profound changes of the lumbar paraspinal muscle, reduction of CSA, increased CSA of IV disc, and increased intramuscu-lar fat infiltration.
Abstract
Background: To investigate the changes of cross sectional area (CSA) in paraspinal mus-cles upon magnetic resonance imaging (MRI) and bone mineral density (BMD) in post-menopausal osteoporotic spinal compression fractures. Methods: We reviewed 81 post-menopausal women with osteoporosis, who had underwent MRI examination. The pa-tients were divided into 51 patients who had osteoporotic spinal compression fractures (group I), and 30 patients who without fractures (group II). Group I were subdivided into IA and IB, based on whether they were younger (IA) of older (IB) than 70 years of age. We additionally measured body mass index and BMD. The CSA of multifidus, erector spinae,paraspinal muscles, psoas major (PT), and intervertebral (IV) discs were measured. The degree of fatty atrophy was estimated using three grades. Results: The BMD and T-score of group I were significantly lower than those of group II. The CSA of erector spinae, para-spinal muscles, and PT in the group I was significantly smaller than that of group II. The CSA of paraspinal muscles in group IB were significantly smaller than those of group IA. The CSA of erector spinae, mutifidus, and PT in group IB were smaller than those of group IA, but the difference was not statistically significant. Group 1 exhibited greater fat infil-tration in the paraspinal muscle than group II. Conclusions: Postmenopausal osteopo-rotic spinal compression fracture is associated with profound changes of the lumbar paraspinal muscle, reduction of CSA, increased CSA of IV disc, and increased intramuscu-lar fat infiltration.
참고문헌 (28)
- American Society of Clinical Nutrition, "Epidemiologic and methodologic problems in determining nutritional status of older persons. Proceedings of a conference. Albuquerque, New Mexico, October 19-21, 1988", Am J Clin Nutr, 50, pp.1121~1235 (1989)
- Bayramoğlu M, "Relationships between muscle strength and bone mineral density of three body regions in sedentary postmenopausal women", Rheumatol Int, 25, pp.513~517 (2005)
- Riggs BL, "Rates of bone loss in the appendicular and axial skeletons of women. Evidence of substantial vertebral bone loss before menopause", J Clin Invest, 77, pp.1487~1491 (1986)
- Grimby G, "The ageing muscle", Clin Physiol, 3, pp.209~218 (1983)
- Cruz-Jentoft AJ, "Understanding sarcopenia as a geriatric syndrome", Curr Opin Clin Nutr Metab Care, 13, pp.1~7 (2010)
- Cederholm T, "Sarcopenia and fragility fractures", Eur J Phys Rehabil Med, 49, pp.111~117 (2013)
- 김태년, "Sarcopenia: Definition, Epidemiology, and Pathophysiology", 대한골대사학회지, 20(1), pp.1~10 (2013), 대한골대사학회
- Sinaki M, "Muscle strength in osteoporotic versus normal women", Osteoporos Int, 3, pp.8~12 (1993)
- Cunha-Henriques S, "Postmenopausal women with osteoporosis and musculoskeletal status: a comparative cross-sectional study", J Clin Med Res, 3, pp.168~176 (2011)
- Miyakoshi N, "Factors related to spinal mobility in patients with postmenopausal osteoporosis", Osteoporos Int, 16, pp.1871~1874 (2005)
- Balzini L, "Clinical characteristics of flexed posture in elderly women", J Am Geriatr Soc, 51, pp.1419~1426 (2003)
- Keller TS, "Prediction of osteoporotic spinal deformity", Spine (Phila Pa 1976), 28, pp.455~462 (2003)
- Pahor M, "Sarcopenia: clinical evaluation, biological markers and other evaluation tools", J Nutr Health Aging, 13, pp.724~728 (2009)
- Cesari M, "Frailty syndrome and skeletal muscle: results from the Invecchiare in Chianti study", Am J Clin Nutr, 83, pp.1142~1148 (2006)
- Maughan RJ., "Relationship between muscle strength and muscle cross-sectional area. Implications for training", Sports Med, 1, pp.263~269 (1984)
- Jorgensen MJ, "Cross-sectional area of the lumbar back muscles as a function of torso flexion", Clin Biomech (Bristol, Avon), 18, pp.280~286 (2003)
- Chaffin DB, "Lumbar muscle size and locations from CT scans of 96 women of age 40 to 63 years", Clin Biomech (Bristol, Avon), 5, pp.9~16 (1990)
- Ropponen A, "The reliability of paraspinal muscles composition measurements using routine spine MRI and their association with back function", Man Ther, 13, pp.349~356 (2008)
- Kang CH, "MRI of paraspinal muscles in lumbar degenerative kyphosis patients and control patients with chronic low back pain", Clin Radiol, 62, pp.479~486 (2007)
- Ho Jun Lee, "The Relationship between Cross Sectional Area and Strength of Back Muscles in Patients with Chronic Low Back Pain", Annals of Rehabilitation Medicine, 36(2), pp.173~181 (2012), 대한재활의학회
- Mengiardi B, "Fat content of lumbar paraspinal muscles in patients with chronic low back pain and in asymptomatic volunteers: quantification with MR spectroscopy", Radiology, 240, pp.786~792 (2006)
- Sinaki M, "Can strong back extensors prevent vertebral fractures in women with osteoporosis?", Mayo Clin Proc, 71, pp.951~956 (1996)
- McGill SM, "A myoelectrically based dynamic three-dimensional model to predict loads on lumbar spine tissues during lateral bending", J Biomech, 25, pp.395~414 (1992)
- Briggs AM, "The effect of osteoporotic vertebral fracture on predicted spinal loads in vivo", Eur Spine J, 15, pp.1785~1795 (2006)
- Crepaldi G, "Osteoporosis and body composition", J Endocrinol Invest, 30, pp.42~47 (2007)
- Buehring B, "Effect of including historical height and radius BMD measurement on sarco-osteoporosis prevalence", J Cachexia Sarcopenia Muscle, 4, pp.47~54 (2013)
- Verschueren S, "Sarcopenia and its relationship with bone mineral density in middle-aged and elderly European men", Osteoporos Int, 24, pp.87~98 (2013)
- Miyakoshi N, "Prevalence of sarcopenia in Japanese women with osteopenia and osteoporosis", J Bone Miner Metab, 31, pp.556~561 (2013)