Hypertrophic Osteoarthropathy in Patient with Crohn’s Disease: A Case Report
0
조회
0
다운로드
0
인용
0
참고문헌
키워드
초록
Numerous causes of hypertrophic osteoarthropathy (HOA) have been reported. Com-monly, secondary osteoarthropathy accompanies pulmonary diseases such as carcino-ma of the lung, pleural tumors, lung abscesses, and bronchiectasis. However, HOA in in-flammatory bowel disease is a rare complication. There are only a few reports of second-ary HOA with Crohn’s disease. Our purpose was to report another case of HOA in Crohn'sdisease. We describe a case of a 27-year-old man with underlying Crohn’s disease pre-senting with 2 years of pain in multiple joints. Radiographic findings suggested HOA inextremities. We performed a conservative treatment including medication and rehabili-tations. The patient’s symptoms were much improved at the latest follow-up. Althoughnumerous studies on HOA have been published, the pathogenesis of HOA is still unclear. Various treatment modalities were recommended but further studies to uncover thepathogenesis of HOA with Crohn’s disease and to establish a treatment modality areneeded.
Abstract
Numerous causes of hypertrophic osteoarthropathy (HOA) have been reported. Com-monly, secondary osteoarthropathy accompanies pulmonary diseases such as carcino-ma of the lung, pleural tumors, lung abscesses, and bronchiectasis. However, HOA in in-flammatory bowel disease is a rare complication. There are only a few reports of second-ary HOA with Crohn’s disease. Our purpose was to report another case of HOA in Crohn'sdisease. We describe a case of a 27-year-old man with underlying Crohn’s disease pre-senting with 2 years of pain in multiple joints. Radiographic findings suggested HOA inextremities. We performed a conservative treatment including medication and rehabili-tations. The patient’s symptoms were much improved at the latest follow-up. Althoughnumerous studies on HOA have been published, the pathogenesis of HOA is still unclear. Various treatment modalities were recommended but further studies to uncover thepathogenesis of HOA with Crohn’s disease and to establish a treatment modality areneeded.
참고문헌 (11)
- Nguyen S., "Review of current therapies for secondary hypertrophic pulmonary osteoarthropathy", Clin Rheumatol., 30, pp.7~13 (2011)
- Shim YW., "Primary hypertrophic osteoarthropathy accompanied by Crohn's disease: a case report", Yonsei Med J., 38, pp.319~322 (1997)
- Yao Q., "Periostitis and hypertrophic pulmonary osteoarthropathy: report of 2 cases and review of the literature", Semin Arthritis Rheum., 38, pp.458~466 (2009)
- 김태희, "바르톨린 농양으로 오인된 외음부에 생긴크론병의 합병증: 1예", Obstetrics & Gynecology Science, 53(07), pp.657~660 (2010), 대한산부인과학회
- Neale G., "Crohn's disease and diffuse symmetrical periostitis", Gut., 9, pp.383~387 (1968)
- Kozak KR., "Hypertrophic osteoarthropathy pathogenesis: a case highlighting the potential role for cyclo-oxygenase-2-derived prostaglandin E2", Nat Clin Pract Rheumatol., 2, pp.452~456 (2006)
- Johnson JC., "Urine PGE-M: a metabolite of prostaglandin E2 as a potential biomarker of advanced colorectal neoplasia", Clin Gastroenterol Hepatol., 4, pp.1358~1365 (2006)
- Dickinson CJ., "Megakaryocytes and platelet clumps as the cause of finger clubbing", Lancet., 2, pp.1434~1435 (1987)
- Atkinson S., "Vascular endothelial growth factor (VEGF)-A and platelet-derived growth factor (PDGF) play a central role in the pathogenesis of digital clubbing", J Pathol., 203, pp.721~728 (2004)
- Angel-Moreno Maroto A., "Painful hypertrophic osteoarthropathy successfully treated with octreotide. The pathogenetic role of vascular endothelial growth factor (VEGF)", Rheumatology (Oxford)., 44, pp.1326~1327 (2005)
- Jayakar BA., "Treatment of hypertrophic osteoarthropathy with zoledronic acid: case report and review of the literature", Semin Arthritis Rheum., 41, pp.291~296 (2011)
