Relationship between Low Muscle Strength, and Protein Intake: A Preliminary Study of Elderly Patients with Hip Fracture
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Background: The purpose of the present study was to assess the daily protein uptake and its relationship with sarcopenia, as defined by the Asian Working Group for Sarcope- nia (AWGS), among elderly patients with hip fractures. Methods: Forty-seven elderly pa- tients with hip fractures were enrolled in this retrospective observational study. The main outcome measures included protein uptake, muscle mass, and grip strength for sarcopenia in elderly patients. Sarcopenia was diagnosed according to AWGS. Whole- body densitometry was used to measure skeletal muscle mass, and muscle strength was evaluated using handgrip testing. Results: Of 47 patients with hip fractures (12 men and 35 women), 37 (79%) patients exhibited insufficient protein intake (range, 0.01-0.588 g/ kg/day), and 10 (21%) patients exhibited excessive protein intake (range, 1.215-2.121 g/ kg/day). The mean daily protein intake was 56.5 g (range, 7.2–136.0 g). Prevalence of low muscle strength (handgrip strength <18 kg in women and <26 kg in men) was de- tected in 13 (37%) women and 8 (67%) men (P = 0.076). Sarcopenia (lower muscle mass and lower muscle strength) was detected in 9 (26%) women and 6 (50%) men (P = 0.119). Although lower protein intake was marginally associated with sarcopenia (P = 0.189), it was significantly associated with lower grip strength (P = 0.042). Conclu- sions: The present study demonstrated that insufficient protein intake in elderly patients with hip fractures was common, and lower protein intake was significantly associated with lower muscle strength.
Abstract
Background: The purpose of the present study was to assess the daily protein uptake and its relationship with sarcopenia, as defined by the Asian Working Group for Sarcope- nia (AWGS), among elderly patients with hip fractures. Methods: Forty-seven elderly pa- tients with hip fractures were enrolled in this retrospective observational study. The main outcome measures included protein uptake, muscle mass, and grip strength for sarcopenia in elderly patients. Sarcopenia was diagnosed according to AWGS. Whole- body densitometry was used to measure skeletal muscle mass, and muscle strength was evaluated using handgrip testing. Results: Of 47 patients with hip fractures (12 men and 35 women), 37 (79%) patients exhibited insufficient protein intake (range, 0.01-0.588 g/ kg/day), and 10 (21%) patients exhibited excessive protein intake (range, 1.215-2.121 g/ kg/day). The mean daily protein intake was 56.5 g (range, 7.2–136.0 g). Prevalence of low muscle strength (handgrip strength <18 kg in women and <26 kg in men) was de- tected in 13 (37%) women and 8 (67%) men (P = 0.076). Sarcopenia (lower muscle mass and lower muscle strength) was detected in 9 (26%) women and 6 (50%) men (P = 0.119). Although lower protein intake was marginally associated with sarcopenia (P = 0.189), it was significantly associated with lower grip strength (P = 0.042). Conclu- sions: The present study demonstrated that insufficient protein intake in elderly patients with hip fractures was common, and lower protein intake was significantly associated with lower muscle strength.
참고문헌 (20)
- Cao L, "Sarcopenia is recognized as an independent condition by an international classification of disease, tenth revision, clinical modification (ICD-10-CM) code", J Am Med Dir Assoc, 17, pp.675~677 (2016)[DOI]
- Chen LK, "Asian working group for sarcopenia : 2019 consensus update on sarcopenia diagnosis and treatment", J Am Med Dir Assoc, 21, pp.300~307 (2020)[DOI]
- Chen LK, "Sarcopenia in Asia : consensus report of the Asian Working Group for Sarcopenia", J Am Med Dir Assoc, 15, pp.95~101 (2014)[DOI]
- 유준일, "High Prevalence of Sarcopenia in Korean Patients after Hip Fracture: A Case-Control Study", Journal of Korean Medical Science, 31(9), pp.1479~1484 (2016), 대한의학회
- Landi F, "The association between sarcopenia and functional outcomes among older patients with hip fracture undergoing in-hospital rehabilitation", Osteoporos Int, 28, pp.1569~1576 (2017)[DOI]
- 김유근, "Effect of Sarcopenia on Postoperative Mortality in Osteoporotic Hip Fracture Patients", 대한골대사학회지, 25(4), pp.227~233 (2018), 대한골대사학회
- Chang CD, "Effect of sarcopenia on clinical and surgical outcome in elderly patients with proximal femur fractures", Skeletal Radiol, 47, pp.771~777 (2018)[DOI]
- 유준일, "Osteosarcopenia in Patients with Hip Fracture Is Related with High Mortality", Journal of Korean Medical Science, 33(4), pp.37~45 (2018), 대한의학회
- Marzetti E, "Sarcopenia : an overview", Aging Clin Exp Res, 29, pp.11~17 (2017)[DOI]
- Marty E, "A review of sarcopenia : Enhancing awareness of an increasingly prevalent disease", Bone, 105, pp.276~286 (2017)[DOI]
- Yoo JI, "Malnutrition and chronic inflammation as risk factors for sarcopenia in elderly patients with hip fracture", Asia Pac J Clin Nutr, 27, pp.527~532 (2018)[DOI]
- Walrand S, "Optimizing protein intake in aging", Curr Opin Clin Nutr Metab Care, 8, pp.89~94 (2005)[DOI]
- Inoue T, "Undernutrition, sarcopenia, and frailty in fragility hip fracture: Advanced strategies for improving clinical outcomes", Nutrients, 12, pp.3743~ (2020)[DOI]
- Taylor BE, "Guidelines for the Provision and Assessment of Nutrition Support Therapy in the Adult Critically Ill Patient: Society of Critical Care Medicine (SCCM) and American Society for Parenteral and Enteral Nutrition (A.S.P.E.N.)", Crit Care Med, 44, pp.390~438 (2016)[DOI]
- Coelho-Júnior HJ, "Low protein intake is associated with frailty in older adults : A systematic review and meta-analysis of observational studies", Nutrients, 10, pp.1334~ (2018)[DOI]
- Misra D, "Does dietary protein reduce hip fracture risk in elders? The Framingham Osteoporosis Study", Osteoporos Int, 22, pp.345~349 (2011)[DOI]
- Wolfe RR, "Optimal protein intake in the elderly", Clin Nutr, 27, pp.675~684 (2008)[DOI]
- Wolfe RR, "The role of dietary protein in optimizing muscle mass, function and health outcomes in older individuals", Br J Nutr, 108(Suppl 2), pp.S88~S93 (2012)[DOI]
- Volpi E, "Is the optimal level of protein intake for older adults greater than the recommended dietary allowance?", J Gerontol A Biol Sci Med Sci, 68, pp.677~681 (2013)[DOI]
- Eglseer D, "Association between sarcopenia and nutritional status in older adults : A systematic literature review", J Gerontol Nurs, 42, pp.33~41 (2016)[DOI]