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한국 40세 이상 성인의 치주질환, 잔존 치아 수와 고감도 C-반응성 단백의 연관성: 2015 국민건강영양조사 제6기 자료

Association between periodontal disease, number of remaining teeth and high-sensitivity C-reactive protein in Korean adults aged 40 and older: Based on data from 2015 Korea National Health and Nutrition Examination Survey

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Objectives: The purpose of this study was to investigate the relationship between periodontal disease, number of remaining teeth with high-sensitivity C-Reactive protein in Korean adults aged 40 and older. Methods: The study used the Sixth Korea National Health and Nutrition Examination Survey (KNHANES Ⅵ-3), 2015. The study sample consisted of 3,883 aged 40 years or older who had completed the health survey and the health examination. Logistic regression analyses were performed to examine the odds ratios of high-sensitivity C-Reactive protein by periodontal disease and number of remaining teeth, adjusting for demographic characteristics, chronic diseases and oral health behavior�related variables. Results: When the demographic and chronic diseases were adjusted, the risk of high�sensitivity C-Reactive protein (hs-CRP) average 1.23 mg/L or higher was 1.36 times higher in patients with periodontal disease between the ages of 40 and 49, but it was not significant (OR=1.36; 95% CI=0.82-2.23). In addition, in the group of 0~23 remaining teeth aged 40~49 years, the risk of higher than the average 1.23 mg/L of high-sensitivity C-Reactive protein was 2.03 times higher (OR=2.03; 95% CI=1.10-3.74), and 1.49 times higher in 60~69 years (OR=1.07; 95% CI=1.04-2.76). Conclusions: This study found that periodontal disease and tooth loss in Korean adults aged 40 and older was significantly associated with high-sensitivity C-reactive protein.

Abstract

Objectives: The purpose of this study was to investigate the relationship between periodontal disease, number of remaining teeth with high-sensitivity C-Reactive protein in Korean adults aged 40 and older. Methods: The study used the Sixth Korea National Health and Nutrition Examination Survey (KNHANES Ⅵ-3), 2015. The study sample consisted of 3,883 aged 40 years or older who had completed the health survey and the health examination. Logistic regression analyses were performed to examine the odds ratios of high-sensitivity C-Reactive protein by periodontal disease and number of remaining teeth, adjusting for demographic characteristics, chronic diseases and oral health behavior�related variables. Results: When the demographic and chronic diseases were adjusted, the risk of high�sensitivity C-Reactive protein (hs-CRP) average 1.23 mg/L or higher was 1.36 times higher in patients with periodontal disease between the ages of 40 and 49, but it was not significant (OR=1.36; 95% CI=0.82-2.23). In addition, in the group of 0~23 remaining teeth aged 40~49 years, the risk of higher than the average 1.23 mg/L of high-sensitivity C-Reactive protein was 2.03 times higher (OR=2.03; 95% CI=1.10-3.74), and 1.49 times higher in 60~69 years (OR=1.07; 95% CI=1.04-2.76). Conclusions: This study found that periodontal disease and tooth loss in Korean adults aged 40 and older was significantly associated with high-sensitivity C-reactive protein.

참고문헌 (30)

  1. World Health Organization, "Noncommunicable diseases country profiles 2011", World Health Organization, 5~ (2011)
  2. Korea Centers for Disease Control, "2018 Chronic disease status and issues", Korea Centers for Disease Control and Prevention, 6~ (2018)
  3. "Disease classification Frequency Sickness Benefit Status"[URL]
  4. Beck JD, "Dental infections and atherosclerosis", Am Heart J, 138(5), pp.528~533 (1999)[DOI]
  5. Paul IE, "Periodontal disease is associated with increased risk of future cardiovascular diseases", J Evidence Based Dental Practice, 4(2), pp.160~162 (2004)[DOI]
  6. Taylor GW, "Bidirectional interrelationships between diabetes and periodontal diseases: An epidemiologic perspective", Ann Periodontol, 6(1), pp.99~112 (2001)[DOI]
  7. Nagasawa T, "Relationship between periodontitis and diabetes-importance of a clinical study to prove the vicious cycle", Intern Med, 49(10), pp.881~885 (2010)[DOI]
  8. Haverkate F, "Production of C-reactive protein and risk of coronary events in stable and unstable angina. European concerted action on thrombosis and disabilities angina pectoris study group", Lancet, 349, pp.462~466 (1997)
  9. Pearson TA, "Markers of inflammation and cardiovascular disease: application to clinical and public health practice: A statement for healthcare professionals from the centers for disease control and prevention and the american heart association", Circulation, 107(3), pp.499~511 (2003)[DOI]
  10. Ridker PM, "High-sensitivity C-reactive protein: potential adjunct for global risk assessment in the primary prevention of cardiovascular disease", Circulation, 103(13), pp.1813~1818 (2001)[DOI]
  11. Lee SY, "Association between periodontitis and blood lipid levels in a Korean population", J Periodontol, 89, pp.28~35 (2018)[DOI]
  12. 최준선, "만 30세 이상 성인에서 치주염과 고중성지방혈증과의 연관성 : 2015년 국민건강영양조사 자료를 이용하여", 한국치위생학회지, 20(1), pp.53~62 (2020), 한국치위생학회[DOI]
  13. Noack B, "Periodontal infections contribute to elevated systemic C-reactive protein level", J Periodontol, 72(9), pp.1221~1227 (2001)[DOI]
  14. 손소현, "한국 성인의 치주질환과 고감도 C-반응단백질 농도의 상관관계", 한국치위생학회지, 19(6), pp.919~929 (2019), 한국치위생학회[DOI]
  15. The Sixth Korea National Health and Nutrition Examination Survey (KNHANES Ⅵ-3), "Korea Center for Disease Control and Prevention", Korea Center for Disease Control and Prevention, ~ (2015)
  16. Babor TF, "The alcohol use disorders identification test:guidelines for use in primary care", World Health Organization, 15~20 (2001)
  17. Lee SY, "Cut-off points of waist circumference for defining abdominal obesity in the Korean population", J Obes Metab Syndr, 15(1), pp.1~9 (2006)
  18. 원영순, "한국 성인의 치주질환 위험 요인", 대한구강보건학회지, 38(3), pp.176~183 (2014), 대한예방치과·구강보건학회
  19. 이선미, "한국 성인의 전신건강상태와 치주질환과의 관련성 분석 - 2012년도 제 5기 국민건강영양조사 결과 분석 -", 대한구강악안면병리학회지, 39(2), pp.447~456 (2015), 대한구강악안면병리학회[DOI]
  20. 이유희, "성인의 비만과 치주질환과의 융합적 관계", 한국융합학회논문지, 8(11), pp.215~222 (2017), 한국융합학회[DOI]
  21. Anand SS, "C-reactive protein as a screening test for cardiovascular risk in a multiethnic population", Arterioscler Thromb Vasc Biol, 24, pp.1509~1515 (2004)
  22. 이석준, "구강건강행태와 고감도 C-반응성 단백질의 상관관계: 국민건강영양조사 제6기(2015년)자료", 보건정보통계학회지, 43(1), pp.64~69 (2018), 한국보건정보통계학회[DOI]
  23. Kim SK, "The relation of high-sensitivity C-reactive protein with metabolic syndrome in Korean adults: Based on the Korean health and nutrition examination survey, 2015", Korean J Fam Pract, 8(5), pp.684~689 (2018)[DOI]
  24. 성기철, "외견상 건강한 한국인의 혈중 C-Reactive Protein농도와H. Pylori 감염 및 심혈관질환의 다른 위험인자와의 연관성", Korean Circulation Journal, 32(7), pp.573~580 (2002), 대한심장학회
  25. Loos BG, "Elevation of systemic markers related to cardiovascular diseases in the peripheral blood of periodontitis patients", J Periodontol, 71(10), pp.1528~1534 (2000)[DOI]
  26. Lee KO, "Relationship between inequalities in health and inequalities in socioeconomic status", J Korean Acad Community Health Nurs, 12(3), pp.609~619 (2001)
  27. Lee NY, "Relationship between obesity, lifestyle and demographic factors and CRP", Korean Society for the Study of Obesity, 13(2), pp.141~149 (2004)
  28. Morohoshi M, "Glucose-dependent interleukin 6 and tumor necrosis factor production by human peripheral blood monocytes in vitro", Diabetes, 45(7), pp.954~959 (1996)[DOI]
  29. Ylostalo PV, "Self-reported gingivitis and tooth loss poorly predict C-reactive protein levels : a study among Finnish young adults", J Clin Periodontol, 35(2), pp.114~119 (2008)[DOI]
  30. 정재홍, "변연치조골소실 및 치아 상실과 C-Reactive Protein의 연관성에 관한 연구", 석사, 고급치과보철학, pp.2010

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