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논문KCI 등재

통풍 환자에서 콜키친에 의해 유발된 근긴장증을 동반한다발신경병 1예

A Case of Acute Colchicine-induced Polyneuropathy with Myotonia in a Gout Patient

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초록

Colchicine is widely used in gout patients and its complications include neuropathy and myopathy. These complications are more prevalent to patients with kidney failure who have increased serum concentration of the drug. Domestically, there has not been a report of peripheral neuropathy caused by colchicine with exception of patients with renal failure. The authors describe a case of colchicine induced neuropathy with myotonia who had not a renal failure. His myotonia was disappeared with the discontinuation of colchicine.

Abstract

Colchicine is widely used in gout patients and its complications include neuropathy and myopathy. These complications are more prevalent to patients with kidney failure who have increased serum concentration of the drug. Domestically, there has not been a report of peripheral neuropathy caused by colchicine with exception of patients with renal failure. The authors describe a case of colchicine induced neuropathy with myotonia who had not a renal failure. His myotonia was disappeared with the discontinuation of colchicine.

참고문헌 (6)

  1. Choi SS, "Colchicine-induced myopathy and neuropathy", Hong Kong Med J, 5, pp.204~207 (1999)
  2. Kuncl RW, "Colchicine myopathy and neuropathy", N Engl J Med, 316, pp.1562~1568 (1987)
  3. Caglar K, "Colchicine-induced myopathy with myotonia in a patient with chronic renal failure", Clin Neurol Neurosurg, 105, pp.274~276 (2003)
  4. Rutkove SB, "Myotonia in colchicine myoneuropathy", Muscle Nerve, 19, pp.870~875 (1996)
  5. Shinde A, "Accumulation of microtubule-based motor protein in a patient with colchicine myopathy", Neurology, 55, pp.1414~1415 (2000)
  6. 오세호, "베체트병에서 관찰된 콜치신에 의한 근긴장성 근병증 1예", 대한신경과학회지, 21(2), pp.220~223 (2003), 대한신경과학회

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