The Predictive Value of the Electrophysiologic Parameters for the Recovery of the Motor Functions in Patients with Stroke
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Objectives: Objective: We conducted this study to analyze correlations between baseline electrophysiological parameters and baseline motor and functional ones in patients with subacute stroke; to identify the electrophysiological parameters with a predictive value for the motor and functional recovery after a 4-week rehabilitation. Method: We enrolled 60 patients with subacute stroke. Electrophysiological parameters include the Somatosensory evoked potential(SSEP), compound motor action potential (CMAP) and sensory nerve action potential(SNAP) amplitude ratio. Clinical parameters consisted of Korean-Modified Barthel Index (K-MBI), Motricity index (MI) and manual function test (MFT). After a 4-week rehabilitation, we reevaluated the K-MBI, MFT and MI. Results: Ulnar CMAP amplitude ratio had a significant correlation with all the clinical outcome indices. Additionally, a multivariate linear regression analysis revealed that the ulnar CAMP amplitude ratio was a independent predictor for the baseline MI of the upper extremity and K-MBI. The median SSEP amplitude ratio was a independent prognostic factor for the follow-up MI of the upper extremity, MFT and the follow-up K-MBI. Conclusions: Our results indicate not only that the median SSEP amplitude ratio was a prognostic factor for the motor functions and functional recovery but also that the ulnar CMAP amplitude might be an independent predictor for the motor functions and functional recovery in subacute stroke patients.
Abstract
Objectives: Objective: We conducted this study to analyze correlations between baseline electrophysiological parameters and baseline motor and functional ones in patients with subacute stroke; to identify the electrophysiological parameters with a predictive value for the motor and functional recovery after a 4-week rehabilitation. Method: We enrolled 60 patients with subacute stroke. Electrophysiological parameters include the Somatosensory evoked potential(SSEP), compound motor action potential (CMAP) and sensory nerve action potential(SNAP) amplitude ratio. Clinical parameters consisted of Korean-Modified Barthel Index (K-MBI), Motricity index (MI) and manual function test (MFT). After a 4-week rehabilitation, we reevaluated the K-MBI, MFT and MI. Results: Ulnar CMAP amplitude ratio had a significant correlation with all the clinical outcome indices. Additionally, a multivariate linear regression analysis revealed that the ulnar CAMP amplitude ratio was a independent predictor for the baseline MI of the upper extremity and K-MBI. The median SSEP amplitude ratio was a independent prognostic factor for the follow-up MI of the upper extremity, MFT and the follow-up K-MBI. Conclusions: Our results indicate not only that the median SSEP amplitude ratio was a prognostic factor for the motor functions and functional recovery but also that the ulnar CMAP amplitude might be an independent predictor for the motor functions and functional recovery in subacute stroke patients.
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