신경근육접합의 구조 및 생리와 전기진단학적 검사
The Anatomy, Physiology, and Electrophysiologic Study of Neuromuscular Junction
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초록
The principal components of neuromuscular junction (NMJ) include the presynaptic terminal, synapticspace and postsynaptic muscle end-plate. This complex structure converts nerve action potentials intomuscle contraction. One must understand normal NMJ anatomy and physiology in order to interpret thepathophysiological mechanism of NMJ disorders such as Myasthenia Gravis (MG) or Lambert-EatonMyasthenic Syndrome (LEMS). In any patients with symptoms of possible the NMJ disorder, one shouldperform repetitive nerve stimulation (RNS) as part of the electrodiagnostic (EDX) evaluation. Thisreview provides the outline of the anatomy and physiology of NMJ and it also focuses on the EDX evaluationof NMJ disorder. Therefore, the goals of this article are the link NMJ physiology and the patient’sclinical examination to EDX planning to test.
Abstract
The principal components of neuromuscular junction (NMJ) include the presynaptic terminal, synapticspace and postsynaptic muscle end-plate. This complex structure converts nerve action potentials intomuscle contraction. One must understand normal NMJ anatomy and physiology in order to interpret thepathophysiological mechanism of NMJ disorders such as Myasthenia Gravis (MG) or Lambert-EatonMyasthenic Syndrome (LEMS). In any patients with symptoms of possible the NMJ disorder, one shouldperform repetitive nerve stimulation (RNS) as part of the electrodiagnostic (EDX) evaluation. Thisreview provides the outline of the anatomy and physiology of NMJ and it also focuses on the EDX evaluationof NMJ disorder. Therefore, the goals of this article are the link NMJ physiology and the patient’sclinical examination to EDX planning to test.
참고문헌 (22)
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