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독감 예방 접종 후에 발생한 길랑-바레 증후군 - 증례 보고 -

A Case of Guillain-Barre′Syndrome Following Influenza Vaccination

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초록

A 55-year-old man with a history of preceding influenza vaccination was admitted complaining of bilateral weakness of lower extremities, headache, and disequilibrium. Guillain-Barre′Syndrome (GBS) was diagnosed by the neurologic examination and electrophysiological studies. His symptoms progressed relentlessly to the condition requiring mechanical ventilation but he showed near full recovery within two months. Our case reminds us of the possible relationship of influenza vaccination and development of GBS.

Abstract

A 55-year-old man with a history of preceding influenza vaccination was admitted complaining of bilateral weakness of lower extremities, headache, and disequilibrium. Guillain-Barre′Syndrome (GBS) was diagnosed by the neurologic examination and electrophysiological studies. His symptoms progressed relentlessly to the condition requiring mechanical ventilation but he showed near full recovery within two months. Our case reminds us of the possible relationship of influenza vaccination and development of GBS.

참고문헌 (11)

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  7. Schonberger LB, "Guillain-Barre syndrome: its epidemiology and associations with influenza vaccination", Ann Neurol, 9, pp.31~38 (1981)
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  9. Haber P, "Guillain-Barre syndrome following influenza vaccination", JAMA, 292, pp.2478~2481 (2004)
  10. Fletcher DD, "Long-term outcome in patients with Guillain-Barre syndrome requiring mechanical ventilation", Neurology, 54, pp.2311~2315 (2000)
  11. Shattner A, "Consequence or coincidence? The occurrence, pathogenesis and significance of autoimmune manifestations after viral vaccines", Vaccine, 23, pp.3876~3886 (2005)

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