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Changing No Response Rate of Superficial Peroneal Nerve Conduction Study According to Aging in Normal Korean Healthy Adults

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초록

Objective: To investigate the relationship between the absent rates of superficial peroneal sensory nerve action potential (SNAP) and age increase in healthy adults without symptoms of peripheral neuropathy. Method: We recruited 120 healthy adults (240 low extremities) and divided into the age groups 20~29, 30~39, 40~49, 50~59, 60~69 and more than 70 years. All subjects underwent sensory nerve conduction study of superficial peroneal nerve. Diabetic history, exposed to neurotoxic agent, neurologic problem, trauma history on low extremity and pitting edema were excluded in this study. Results: All subjects of age groups 20~29, 30~39, 40~49 and 50~59 years were elicited, but 2 subjects (1.7%) in age group 60~69 years and 7 subjects (5.8%) in age group more than 70 years were not elicited. Increasing age and the no response rate of superficial peroneal nerve conduction study were correlated statically significant (p-value = 0.004). Using a receiver operator characteristic (ROC) curve, absent superficial peroneal SNAP could be observed more than 70.5 years with sensitivity of 77.8% and specificity of 89.2%. Conclusion: The ratio of absent superficial peroneal SNAP can be increase in elderly healthy adults. This study shows reference that superficial peroneal SNAP might be absent as age increase.

Abstract

Objective: To investigate the relationship between the absent rates of superficial peroneal sensory nerve action potential (SNAP) and age increase in healthy adults without symptoms of peripheral neuropathy. Method: We recruited 120 healthy adults (240 low extremities) and divided into the age groups 20~29, 30~39, 40~49, 50~59, 60~69 and more than 70 years. All subjects underwent sensory nerve conduction study of superficial peroneal nerve. Diabetic history, exposed to neurotoxic agent, neurologic problem, trauma history on low extremity and pitting edema were excluded in this study. Results: All subjects of age groups 20~29, 30~39, 40~49 and 50~59 years were elicited, but 2 subjects (1.7%) in age group 60~69 years and 7 subjects (5.8%) in age group more than 70 years were not elicited. Increasing age and the no response rate of superficial peroneal nerve conduction study were correlated statically significant (p-value = 0.004). Using a receiver operator characteristic (ROC) curve, absent superficial peroneal SNAP could be observed more than 70.5 years with sensitivity of 77.8% and specificity of 89.2%. Conclusion: The ratio of absent superficial peroneal SNAP can be increase in elderly healthy adults. This study shows reference that superficial peroneal SNAP might be absent as age increase.

참고문헌 (11)

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