Hydroxychloroquine 치료 후 38일과 40일에 재발한 삼일열 말라리아 2예
Two Cases of Vivax Malaria Recurred at 38 and 40 Days afterHydoxychloroquine Therapy
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초록
전세계적으로 삼일열 말라리아는 재발을 잘하는 말라리아로 보고되고 있으나 최근 우리나라에 재유행한 삼일열 말라리아의 재발에 대한 보고는 드물어 원인 추정과 함께 2 예를 보고하는 바이다.
Abstract
There are two stages in the life circle of Plasmodiumspp in humans: exoerythrocytic and erythrocytic stages. Hydroxychloroquine is the major chemotherapeutic agent against malarial parasites in their erythrocytic stage. The recurrence of Plasmodium vivax malaria, which is usually caused by an inadequate treatment or the presence of drug resistant parasites, has been reported frequently in the world, but rarely in Korea. We experienced two patients who recurred with P. vivaxmalaria after hydroxychloroquine therapy, and treating with insufficient doses of the drug was suspected as the cause of the recurrence.
참고문헌 (12)
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