Taenia saginata infection incidentally detected during workup for lymphoma from an 8-year-old boy in Korea: a case report
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Human taeniasis is presumed to have almost disappeared from Korea. Recently, weincidentally detected a Taenia saginata infection in an 8-year-old boy undergoing lymphomadiagnosis. The patient had been suffering for 4 months from intensifying snoring andobstructive sleep apnea. A neck computed tomography scan revealed a nasopharyngealmass, and malignant B-cell lymphoma was supported by punch biopsy. On day 6 of thelymphoma workup period, the patient experienced anal itching, and two proglottids weredetected in his stool. The patient had experienced four or five similar episodes within thepast 2 years. He self-reported a history of raw beef and fish consumption and no history oftraveling abroad. Laboratory findings revealed mild eosinophilia (eosinophil count: 791/μL). Two proglottids exhibited movement and possessed more than 15 branched uterinestructures. Long segments approximately 84 cm in length were expelled after praziquanteltreatment. Sequencing of the cytochrome oxidase 1 gene confirmed T. saginata, ruling outrelated Taenia species. After treatment, no proglottids or ova were detected in his stool, andthe patient finally started chemotherapy for lymphoma. This case highlights the importanceof timely diagnosis of hidden taeniasis in low-frequency endemic regions.
Abstract
Human taeniasis is presumed to have almost disappeared from Korea. Recently, weincidentally detected a Taenia saginata infection in an 8-year-old boy undergoing lymphomadiagnosis. The patient had been suffering for 4 months from intensifying snoring andobstructive sleep apnea. A neck computed tomography scan revealed a nasopharyngealmass, and malignant B-cell lymphoma was supported by punch biopsy. On day 6 of thelymphoma workup period, the patient experienced anal itching, and two proglottids weredetected in his stool. The patient had experienced four or five similar episodes within thepast 2 years. He self-reported a history of raw beef and fish consumption and no history oftraveling abroad. Laboratory findings revealed mild eosinophilia (eosinophil count: 791/μL). Two proglottids exhibited movement and possessed more than 15 branched uterinestructures. Long segments approximately 84 cm in length were expelled after praziquanteltreatment. Sequencing of the cytochrome oxidase 1 gene confirmed T. saginata, ruling outrelated Taenia species. After treatment, no proglottids or ova were detected in his stool, andthe patient finally started chemotherapy for lymphoma. This case highlights the importanceof timely diagnosis of hidden taeniasis in low-frequency endemic regions.
참고문헌 (9)
- Dorny P, "Taenia saginata in Europe", Vet Parasitol, 149, pp.22~24 (2007)
- Braae UC, "Epidemiology of Taenia saginata taeniosis", cysticercosis : a systematic review of the distribution in the Americas, 2018, pp.11, 518~
- National survey of intestinal parasitic infections in Korea. 8th report; 2013, "Korea Centers for Disease Control and Prevention", KCDC, 89~94 (2014)
- Eun Jeong Won, "Four Taeniasis saginata Cases Diagnosed at a University Hospital in Korea", Parasites, Hosts and Diseases, 57(3), pp.313~318 (2019), 대한기생충학ㆍ열대의학회[DOI]
- Su-Min Song, "Ten Cases of Taenia saginata Infection Confirmed by Analysis of the Internal Transcribed Spacer 1 rDNA Region in the Republic of Korea", Parasites, Hosts and Diseases, 57(4), pp.417~422 (2019), 대한기생충학ㆍ열대의학회[DOI]
- Jeon HK, "Molecular identification of Taenia specimens after long-term preservation in formalin", Parasitol Int, 60, pp.203~205 (2011)
- Thompson JD, "CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice", Nucleic Acids Res, 22, pp.4673~4680 (1994)
- Saitou N, "The neighbor-joining method : a new method for reconstructing phylogenetic trees", Mol Biol Evol, 4, pp.406~425 (1987)
- 채종일, "Human Taeniasis in the Republic of Korea: Hidden or Gone?", Parasites, Hosts and Diseases, 51(1), pp.9~17 (2013), 대한기생충학ㆍ열대의학회