Clinical and Microbiological Risk Factors for Community-Associated Clostridioides difficile Infections
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초록
Background: The incidence of community-associated (CA) Clostridioides difficile infection(CDI) has increased in Korea. In this study, we evaluated CA-CDI risk factors in terms of clinicalfeatures and ribotype considering its region-specific molecular epidemiology. Methods: A retrospective case-control study was performed on two groups of CDI patients:127 subjects with CA-CDI and 265 subjects with healthcare-associated (HA)-CDI. Risk factorsfor CA-CDI were evaluated in terms of clinical and microbiological features such as toxin typeand ribotype. Results: A comparison of the two groups of CDI patients revealed that inflammatory boweldisease, diarrhea, abdominal pain, and fever were more closely associated with CA-CDI. Thetoxin types and ribotypes of C. difficile were similar between the two groups. After adjustingfor variables, no risk factors were identified for CA-CDI compared with HA-CDI. Conclusion: Specific risk factors for CA-CDI were not identified in this study.
Abstract
Background: The incidence of community-associated (CA) Clostridioides difficile infection(CDI) has increased in Korea. In this study, we evaluated CA-CDI risk factors in terms of clinicalfeatures and ribotype considering its region-specific molecular epidemiology. Methods: A retrospective case-control study was performed on two groups of CDI patients:127 subjects with CA-CDI and 265 subjects with healthcare-associated (HA)-CDI. Risk factorsfor CA-CDI were evaluated in terms of clinical and microbiological features such as toxin typeand ribotype. Results: A comparison of the two groups of CDI patients revealed that inflammatory boweldisease, diarrhea, abdominal pain, and fever were more closely associated with CA-CDI. Thetoxin types and ribotypes of C. difficile were similar between the two groups. After adjustingfor variables, no risk factors were identified for CA-CDI compared with HA-CDI. Conclusion: Specific risk factors for CA-CDI were not identified in this study.
참고문헌 (11)
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