개 대망의 악성 중피종
Malignant mesothelioma of omentum in a dog
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An 8-year old intact female poodle was presented to clinics due to abdominal distension, anorexia, and labored breath associated with pleural effusion. Intra-operative findings revealed multiple neoplasm of the greater omentum, involving anterolateral abdominal wall, sterna surface in the pleural cavity and diaphragm. These masses were 0.1∼0.5 cm in diameter and extended to ovaries, pancreas, and serosal surface of stomach. Microscopically, most neoplastic cells had oval nuclei with prominent nucleoli and abundant eosinophilic cytoplasm. In deeper area, neoplastic acinus or glandular structures showed in-vaginated growth resembling adenocarcinoma. High mitotic figures were observed. By immunohisto-chemistry, the neoplastic cells were strong positive both cytokeratin and vimentin. The present case de-scribed for malignant mesothelioma in a dog. Our findings might be helpful for diagnosis and in-formation and helped the clinics choose the treatment including chemotherapy such as cisplatin.
Abstract
An 8-year old intact female poodle was presented to clinics due to abdominal distension, anorexia, and labored breath associated with pleural effusion. Intra-operative findings revealed multiple neoplasm of the greater omentum, involving anterolateral abdominal wall, sterna surface in the pleural cavity and diaphragm. These masses were 0.1∼0.5 cm in diameter and extended to ovaries, pancreas, and serosal surface of stomach. Microscopically, most neoplastic cells had oval nuclei with prominent nucleoli and abundant eosinophilic cytoplasm. In deeper area, neoplastic acinus or glandular structures showed in-vaginated growth resembling adenocarcinoma. High mitotic figures were observed. By immunohisto-chemistry, the neoplastic cells were strong positive both cytokeratin and vimentin. The present case de-scribed for malignant mesothelioma in a dog. Our findings might be helpful for diagnosis and in-formation and helped the clinics choose the treatment including chemotherapy such as cisplatin.
참고문헌 (12)
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