50세 이상 한국 남성의 알코올과 흡연력이 골밀도에 미치는 영향에 대한 복합표본 분석
Complex Sample Analysis of the Effect of Alcohol Drinking and Smoking Period on Bone Mineral Densities in Korean Men Aged 50 Years and Over
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Purpose: This study aimed to identify the effect of the level of alcohol drinking and smoking period on the occurrence of lumbar and femoral neck osteoporosis in men aged 50 years and over. Methods: This study analyzed the data of 1,410 men based on results of a National Survey on Nutritional Health for the period 2010-2012. Complex sample multi-variate logistic regression analysis was conducted to determine whether alcohol drinking and smoking period were associated with osteoporosis in men aged 50 years older. Results: The risk of osteoporosis in the femoral neck was 3.43 times (95% confidence interval [CI]=1.15~10.29) higher in men who consumed less alcohol and smoked for a long time comparedto men who smoked more than 40 years and consumed much alcohol at once. The risk of osteoporosis in the lumbar spine was 3.45 times (95% confidence interval [CI]=1.69~7.04) higher respectively. Men who consumed much alcohol at a time and smoked less than 40 years were 1.54 (1/0.65) times (95% confidence interval [CI]=0.45~0.93) more likely to be classified as normal than the men who consumed much alcohol and had a long smoking period. Conclusion: The interaction of excessive drinking and smoking has a more detrimental effect on bone mineral density.
Abstract
Purpose: This study aimed to identify the effect of the level of alcohol drinking and smoking period on the occurrence of lumbar and femoral neck osteoporosis in men aged 50 years and over. Methods: This study analyzed the data of 1,410 men based on results of a National Survey on Nutritional Health for the period 2010-2012. Complex sample multi-variate logistic regression analysis was conducted to determine whether alcohol drinking and smoking period were associated with osteoporosis in men aged 50 years older. Results: The risk of osteoporosis in the femoral neck was 3.43 times (95% confidence interval [CI]=1.15~10.29) higher in men who consumed less alcohol and smoked for a long time comparedto men who smoked more than 40 years and consumed much alcohol at once. The risk of osteoporosis in the lumbar spine was 3.45 times (95% confidence interval [CI]=1.69~7.04) higher respectively. Men who consumed much alcohol at a time and smoked less than 40 years were 1.54 (1/0.65) times (95% confidence interval [CI]=0.45~0.93) more likely to be classified as normal than the men who consumed much alcohol and had a long smoking period. Conclusion: The interaction of excessive drinking and smoking has a more detrimental effect on bone mineral density.
참고문헌 (29)
- Karina M. Berg, "Association Between Alcohol Consumption and Both Osteoporotic Fracture and Bone Density", The American Journal of Medicine, 121(5), pp.406~418 (2008), Elsevier BV[DOI]
- Billie Bonevski, "Associations between alcohol, smoking, socioeconomic status and comorbidities: Evidence from the 45 and Up Study", Drug and Alcohol Review, 33(2), pp.169~176 (2014), Wiley[DOI]
- John J. Callaci, "The Effects of Binge Alcohol Exposure on Bone Resorption and Biomechanical and Structural Properties are Offset by Concurrent Bisphosphonate Treatment", Alcoholism: Clinical & Experimental Research, 28(1), pp.182~191 (2004), Wiley[DOI]
- Peggy M. Cawthon, "Alcohol Intake and Its Relationship with Bone Mineral Density, Falls, and Fracture Risk in Older Men", Journal of the American Geriatrics Society, 54(11), pp.1649~1657 (2006), Wiley[DOI]
- Yoosun Cho, "Association between alcohol consumption and bone mineral density in elderly Korean men and women", Archives of Osteoporosis, 13(1), pp.46~ (2018), Springer Nature[DOI]
- Fini, M, "Role of obesity, alcohol and smoking on bone health", Frontiers in Bioscience(Elite edition), 4, pp.2586~2606 (2012)
- Rafael Gómez Navarro, "Prevalencia de los factores de riesgo de fractura por fragilidad en varones de 40 a 90 años de una zona básica de salud rural", Revista Española de Salud Pública, 85(5), pp.491~498 (2011), FapUNIFESP (SciELO)[DOI]
- González-Reimers, E, "Serum sclerostin in alcoholics: A pilot study", Alcohol and Alcoholism, 48(3), pp.278~282 (2013)[DOI]
- Marian T. Hannan, "Risk Factors for Longitudinal Bone Loss in Elderly Men and Women: The Framingham Osteoporosis Study", Journal of Bone and Mineral Research, 15(4), pp.710~720 (2000), Wiley[DOI]
- G. Holt, "Gender differences in epidemiology and outcome after hip fracture", The Journal of Bone and Joint Surgery. British volume, 90-B(4), pp.480~483 (2008), British Editorial Society of Bone & Joint Surgery[DOI]
- 홍지연, "생애주기별 남성 음주자의 문제음주 영향요인에 관한 연구", 성인간호학회지, 26(2), pp.139~148 (2014), 한국성인간호학회[DOI]
- John A. Kanis, "Alcohol intake as a risk factor for fracture", Osteoporosis International, 16(7), pp.737~742 (2005), Springer Nature[DOI]
- J. A. Kanis, "Smoking and fracture risk: a meta-analysis", Osteoporosis International, 16(2), pp.155~162 (2005), Springer Nature[DOI]
- 김은해, "성인 남성에서 골밀도와 관련된 생화학적 지표 및 생활습관 요인", Korean Journal of Family Medicine, 30(5), pp.359~368 (2009), 대한가정의학회
- 김영란, "60세 이상 노년 한국 남성들의 골밀도 수준 및 관련요인", 한국산학기술학회논문지, 14(3), pp.1180~1190 (2013), 한국산학기술학회[DOI]
- 이동하, "남성의 골밀도 영향요인", 근관절건강학회지, 18(1), pp.5~15 (2011), 대한근관절건강학회
- 이혜상, "우리나라 성인 남성의 골밀도에 연관성을 보이는 요인 : 국민건강영양조사자료, 2010∼2011", 대한지역사회영양학회지, 22(2), pp.136~144 (2017), 대한지역사회영양학회[DOI]
- Young Woo Lee, "Effect of Quantity and Frequency of Alcohol Consumption on Bone Mineral Density in Korean Adult Men: The Fifth Korean National Health and Nutrition Examination Survey 2010-2011", Korean Journal of Family Practice, 8(2), pp.207~213 (2018), The Korean Academy of Family Medicine[DOI]
- A. C. Looker, "Trends in osteoporosis and low bone mass in older US adults, 2005–2006 through 2013–2014", Osteoporosis International, 28(6), pp.1979~1988 (2017), Springer Nature[DOI]
- Peter Mikosch, "Alkohol und Knochen", Wiener Medizinische Wochenschrift, 164(1-2), pp.15~24 (2014), Springer Nature[DOI]
- A. Moghaddam, "Cigarette smoking decreases TGF-β1 serum concentrations after long bone fracture", Injury, 41(10), pp.1020~1025 (2010), Elsevier BV[DOI]
- A. G. Need, "Relationships Between Intestinal Calcium Absorption, Serum Vitamin D Metabolites and Smoking in Postmenopausal Women", Osteoporosis International, 13(1), pp.83~88 (2002), Springer Nature[DOI]
- 오기원, "한국인 중년남성에서 골밀도에 관련된 인자", 대한내과학회지, 65(3), pp.315~322 (2003), 대한내과학회
- 박혜진, "한국 성인의 문제 음주 유병률 및 위험요인", 한국산학기술학회논문지, 19(1), pp.389~397 (2018), 한국산학기술학회[DOI]
- C. Sioka, "Smoking and alcohol use as risk factors for low bone mineral density", Rheumatology International, 27(2), pp.207~208 (2006), Springer Nature[DOI]
- Kuen Tak Suh, "Decreased Osteogenic Differentiation of Mesenchymal Stem Cells in Alcohol-induced Osteonecrosis", Clinical Orthopaedics and Related Research, (431), pp.220~225 (2005), Ovid Technologies (Wolters Kluwer Health)[DOI]
- A. Tenenhouse, "Estimation of the Prevalence of Low Bone Density in Canadian Women and Men Using a Population-Specific DXA Reference Standard: The Canadian Multicentre Osteoporosis Study (CaMos)", Osteoporosis International, 11(10), pp.897~904 (2000), Springer Nature[DOI]
- S. W. Wade, "Estimating prevalence of osteoporosis: examples from industrialized countries", Archives of Osteoporosis, 9(1), pp.182~ (2014), Springer Nature[DOI]
- Nelson B. Watts, "Osteoporosis in Men: An Endocrine Society Clinical Practice Guideline", The Journal of Clinical Endocrinology & Metabolism, 97(6), pp.1802~1822 (2012), The Endocrine Society[DOI]