한국산 겨우살이의 산화적 DNA 손상 억제작용
Inhibitory effect of Korean mistletoes on the oxidative DNA damage
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Abstract
Korean mistletoes extracts were investigated for in vitro antioxidation activity, with 1,1-diphenyl-2-picrylhydrazine(DPPH), and an ingibitory effect on oxidative DNA damage by using comet assay. The Korean mistletoes were 4 different kinds classified by their host plnats (Korean Viscum sp. in Quercus acutissima Carr., Korean Viscum sp. in Castanea crenata, Korean Viscum sp. in Betula platyphylla, and Korean Viscum sp. in Salix koreensis). The samples were extracted with ethanol, and fractonationed with η-butanol, Korean Viscum sp. in Betula platyphylla showed the strongest activities to electron donating ability on ,1-diphenyl-2-picrylhydrazyl(DPPH) and the protective effect on oxidative DNA damage.