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Production of Tropane Alkaloids by Optimal CultureConditions in Adventitious Root of Hyoscyamus niger L.

Myung Suk Choi|Dong Jin Park|Ji Yun Min|Yong Duck Kim|Seung Mi Kang|Ha Na Jung|Hoon Serg Kang
한국약용작물학회|2005.10|한국약용작물학회지 (KOREAN JOURNAL OF MEDICINAL CROP SCIENCE)|제13권 제5호|pp. 237-241

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Abstract

Scopolamine and hyoscyamine are important anticholinergic compounds obtained from Hyoscyamus niger. Adventitious roots induced from rhizome of H. niger and roots were cultured in SH medium supplemented with 3% (w/v) sucrose and 0.5㎎/L IBA. Roots were grown rapidly after 10 days of cultures. Scopolamine production was increased 7 times and hyoscyamine production was increased 12 times after 10 day of cultures. SH medium was best in root growth. But, highest scopolamine productivity was observed in WPM medium, followed White medium and best hyoscyamine productivity was resulted in MS medium. Sucrose was increased scopolamine and hyoscyamine production were increased the medium supplemented by sucrose comparing to than those by other carbon sources.

참고문헌 (20)

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관련 논문AI추천

Production of Tropane Alkaloids by Two-stage Culture of Scopolia parviflora Nakai Adventitious Root김운정한국약용작물학회 · 한국약용작물학회지2004 · 제12권 제5호Growth Pattern and Content of Tropane Alkaloids of Metabolic Engineered Scopolia parviflora Hairy Root LinesYoung Min Kang한국약용작물학회 · 한국약용작물학회지2004 · 제12권 제2호미치광이풀 모상근 배양에서 Tropane Alkaloids 생산성 증진을 위한 최적 생물학적 엘리시터 선발강승미, 강영민, 김용덕, 양재경, 정영관, 정희영, 최명석한국약용작물학회 · 한국약용작물학회지2003 · 제11권 제5호Optimization of Aconitine Production in Suspension Cell Cultures of Aconitum napellus L.황성진한국약용작물학회 · 한국약용작물학회지2004 · 제12권 제5호Effects of Elicitors on Scopolamine Production of Scopolia parviflora Nakai Adventitious Roots in Bubble Column Bioreactor정희영한국약용작물학회 · 한국약용작물학회지2004 · 제12권 제5호The First Step of Biotechnological Approaches for Alkaloid Biosynthesis in Papaveraceae: In vitro Plant Regenerations박상운한국약용작물학회 · 한국약용작물학회지2004 · 제12권 제5호

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