큰꽃삽주의 생육 특성 및 유효성분 함량 변이
Growth Characteristics and Change of Major Components in Atractylodes macrocephala
2
조회
0
다운로드
0
인용
0
참고문헌
키워드
초록
Background: The rhizome of Atractylodes macrocephala is used in traditional medicine. Atractylenolides I, II and III are the major components used in traditional medicine and possess gastroprotective properties. Although the domestic cultivation and production scale of A. macrocephalaare currently expanding, research on cultivation physiology remains insufficient. Methods and Results: A. macrocephala seeds were sown in a greenhouse in mid-March, and the seedlings were transplanted in mid-May to investigate growth characteristics and atractylenolide content on a monthly basis. While the shoot growth decreased after peaking in mid-October, the growth of the rhizome increased sharply from mid-June to mid-July and continued to increase until mid-November. The length of the rhizome increased until mid-October, and then stopped, but its diameter continued to increased steadily until mid-November. The total content of the three atractylenolides was the highest in mid-November followed by mid-August. Conclusions: Growth of the rhizome continued until mid-November, when the shoot had dried, and the active content was highest at this time, followed by mid-August before flowering. These findings provide basic imformation regarding the phsiology of A. macrocephala that can be useful to researchers and farmers.
Abstract
Background: The rhizome of Atractylodes macrocephala is used in traditional medicine. Atractylenolides I, II and III are the major components used in traditional medicine and possess gastroprotective properties. Although the domestic cultivation and production scale of A. macrocephalaare currently expanding, research on cultivation physiology remains insufficient. Methods and Results: A. macrocephala seeds were sown in a greenhouse in mid-March, and the seedlings were transplanted in mid-May to investigate growth characteristics and atractylenolide content on a monthly basis. While the shoot growth decreased after peaking in mid-October, the growth of the rhizome increased sharply from mid-June to mid-July and continued to increase until mid-November. The length of the rhizome increased until mid-October, and then stopped, but its diameter continued to increased steadily until mid-November. The total content of the three atractylenolides was the highest in mid-November followed by mid-August. Conclusions: Growth of the rhizome continued until mid-November, when the shoot had dried, and the active content was highest at this time, followed by mid-August before flowering. These findings provide basic imformation regarding the phsiology of A. macrocephala that can be useful to researchers and farmers.
참고문헌 (41)
- 안찬훈, "천속단의 수확시기에 따른 수량과 Loganin 성분 변이", 한국약용작물학회지, 24(2), pp.110~114 (2016), 한국약용작물학회[DOI]
- "Animal and Plant Quarantine Agence(APQA)" (2020)[URL]
- Baraldi R, "Distribution of artemisinin and bioactive flavonoids from Artemisia annua L. during plant growth", Biochemical Systematics and Ecology, 36, pp.340~348 (2008)
- Cheng Y, "Antiviral activities of atractylon from Atractylodis rhizoma", Molecular Medicine Reports, 14, pp.3704~3710 (2016)
- 조준형, "포장조건에 따른 백출의 역병 발생", 한국약용작물학회지, 9(3), pp.211~219 (2001), 한국약용작물학회
- Cho JH, "Study on quantitative growth analysis in yam(Dioscorea sp. )", Korean Journal of Medicinal Crop Science, 8, pp.362~372 (2000)
- 한정훈, "백출 지상부의 항산화 성분", 약 학 회 지, 51(2), pp.88~95 (2007), 대한약학회
- Hoffmann WA, "Avoiding bias in calculations of relative growth rate", Annals of Botany, 90, pp.37~42 (2002)
- Hwang JM, "Inhibitory effect of atractylon on tert-butyl hydroperoxide induced DNA damage and hepatic toxicity in rat hepatocytes", Archives of Toxicology, 70, pp.640~644 (1996)
- 정의민, "한의학 고전 문헌과 현대 약리 연구에서 보고된 백출(白朮)의 효능에 관한 비교연구", 한약정보연구회지(韓藥情報硏究會誌), 3(2), pp.1~16 (2015), 한약정보연구회[DOI]
- 김정훈, "朮類 한약재의 외․내부형태와 이화학패턴 연구", 대한본초학회지, 24(2), pp.77~85 (2009), 대한본초학회
- Kim KJ, "Changes of root yield and paeoniflorin content by cultivated years in Paeonia lactiflora Palls", Korean Journal of Medicinal Crop Science, 4, pp.68~73 (1996)
- Kwan Su Kim, "Evaluation of Sesquiterpenoids Content and Growth Characters inClonal Lines from a Cross between Atractylodes japonicaKoidz. ex Kitam. and A. macrocephala Koidz.", 한국약용작물학회지, 14(2), pp.107~112 (2006), 한국약용작물학회
- Kim SY, "Effects of flower removal on growth and content of essential oil in Atractylodes macrocephala Koidz", Korean Journal of Plant Resources, 14, pp.152~156 (2001)
- 김영국, "단삼의 수확시기에 따른 생육 특성 및 주요 성분 변이", 한국약용작물학회지, 23(5), pp.395~399 (2015), 한국약용작물학회[DOI]
- "Nongjeonghoeyo" (2010)[URL]
- "Jeungbosallimgyeongje" (2010)[URL]
- 이정훈, "황해쑥(Artemisia argyi H.Lév. & Vaniot)의 작물 특성과 플라보노이드 함량", 원예과학기술지, 36(5), pp.647~657 (2018), 한국원예학회
- 이상훈, "지황의 비대시기와 수확시기 구명 연구", 한국약용작물학회지, 27(5), pp.315~321 (2019), 한국약용작물학회[DOI]
- 이상훈, "미네랄 및 호르몬 제제 처리에 따른 당귀의 생육특성 및 Decursin, Decursinol Angelate 함량 변화", 한국약용작물학회지, 26(3), pp.227~232 (2018), 한국약용작물학회[DOI]
- 이성옥, "백출 추출물의 암세포증식 저해 효과", 생약학회지, 36(3), pp.201~204 (2005), 한국생약학회
- Lee ST, "Crude saponin contents of Platycodon grandiflorum(Jacq. )A. DC", Korean Journal of Medicinal Crop Science, 7, pp.172~176 (1999)
- Li C, "Atractylenolide I and Atractylenolide III inhibit lipopolysaccharide-induced TNF-αand NO production in macrophages", Phytotherapy Research, 22, pp.557~559 (2009)
- 임현, "Effects of the Rhizomes of Atractylodes japonica and Atractylenolide I on Allergic Response and Experimental Atopic Dermatitis", Archives of Pharmacal Research, 35(11), pp.2007~2012 (2012), 대한약학회
- Matsuda H, "Imaging analysis of antiulcer action and the active constituent of atractylodis rhizoma", Journal of the Pharmaceutical Society of Japan, 111, pp.36~39 (1991)
- Ministry of Agriculture, Food and Rural Affair(MAFRA)., "Final results of the 2020 census of agriculture, forestry and fisheries", Ministry of Agriculture, Food and Rural Affairs, 6~41 (2020)
- "Food standards and specifications" (2020)[URL]
- Park JM, "Growth and yield of Atractylodes japonica Koidz. affected by shading and flower bud pinching", Korean Journal Medicinal Crop Science, 12, pp.231~236 (2014)
- Rees M, "Partitioning the components of relative growth rate: How important is plant size variation?", The American Naturalist, 176, pp.152~161 (2010)
- Rural Development Administration(RDA)., "A collection of agricultural technology in the field of medicinal crops", Rural Development Administration, 458~ (2005)
- Rural Development Administration(RDA)., "Manual for agriculture investigation", Rural Development Administration, 771~835 (2012)
- Rural Development Administration(RDA)., "Manual for agriculture investigation", Rural Development Administration, 503~ (2012)
- Rural Development Administration(RDA)., "GAP standard cultivation techniques in medicinal crops", Rural Development Administration, 131~133 (2016)
- Rural Development Administration(RDA), "Atractylodes rhizome white. Agriculture technology guide 218", Rural Development Administration, 30~31 (2018)
- "Data by period of agricultural meteorology" (2019)[URL]
- Satoh K, "Specific inhibition of Na+, K+-ATPase activity by atractylon, a major component of Byaku-Jutsu, by interaction with enzyme in the E2 state", Biochemical Pharmacology, 51, pp.339~343 (1996)
- 서태철, "DQI와 단기 상대생장률 분석을 이용한 원통형 종이포트 토마토 접목묘의 우량묘 기준 설정", 생물환경조절학회지, 27(4), pp.302~311 (2018), (사) 한국생물환경조절학회[DOI]
- Wang C, "Inhibitory effect of atractylenolide I on angiogenesis in chronic inflammation in vivo and in vitro", European Journal of Pharmacology, 612, pp.143~152 (2009)
- Wang CC, "Cytotoxic activity of sesquiterpenoids from Atractylodes Ovata on leukemia cell lines", Planta Medica, 68, pp.204~208 (2002)
- Wang KT, "Gastroprotective activity of atractylenolide III from Atractylodes ovata on ethanol-induced gastric ulcer in vitro and in vivo", Journal of Pharmacy and Pharmacology, 62, pp.381~388 (2010)
- 윤보라, "백출의 Atractylenolide I과 Atractylenolide III의 함량분석", 생약학회지, 44(1), pp.53~59 (2013), 한국생약학회