골아세포가 배양된 치과 임플란트용 Ti-Ta합금의 전기화학적 특성
Electrochemical Characteristics of Osteoblast Cultured Ti-Ta Alloy for Dental Implant
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Electrochemical behaviors of surface modified and MC3T3-E1 cell cultured Ti-30Ta alloys have been investigated using various electrochemical methods. The Ti alloys containing Ta were melted by using a vacuum furnace and then homogenized for 6 hrs at 1000oC. MC3T3-E1 cell culture was performed with MC3T3-E1 mouse osteoblasts for 2 days. The microstructures and corrosion resistance were measured using FE-SEM, XRD, EIS and potentiodynamic test in artificial saliva solution at 36.5℃. Ti-Ta alloy showed the martensite structure of a+b phase and micro-structure was changed from lamellar structure to needle-like structure as Ta content increased.Corrosion resistance increased as Ta content increased. Corrosion resistance of cell cultured Ti-Ta alloy increased predominantly in compared with non cell cultured Ti-Ta alloy due to inhibition of the dissolution of metal ion by covered cell. Rp value of MC3T3-E1 cell cultured Ti-40 Ta alloy showed 1.60106 Wcm2 which was higher than those of other Ti alloy. Polarization resistance of cell-cultured Ti-Ta alloy increased in compared with non-cell cultured Ti alloy.
Abstract
Electrochemical behaviors of surface modified and MC3T3-E1 cell cultured Ti-30Ta alloys have been investigated using various electrochemical methods. The Ti alloys containing Ta were melted by using a vacuum furnace and then homogenized for 6 hrs at 1000oC. MC3T3-E1 cell culture was performed with MC3T3-E1 mouse osteoblasts for 2 days. The microstructures and corrosion resistance were measured using FE-SEM, XRD, EIS and potentiodynamic test in artificial saliva solution at 36.5℃. Ti-Ta alloy showed the martensite structure of a+b phase and micro-structure was changed from lamellar structure to needle-like structure as Ta content increased.Corrosion resistance increased as Ta content increased. Corrosion resistance of cell cultured Ti-Ta alloy increased predominantly in compared with non cell cultured Ti-Ta alloy due to inhibition of the dissolution of metal ion by covered cell. Rp value of MC3T3-E1 cell cultured Ti-40 Ta alloy showed 1.60106 Wcm2 which was higher than those of other Ti alloy. Polarization resistance of cell-cultured Ti-Ta alloy increased in compared with non-cell cultured Ti alloy.
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