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흡수성이 우수한 창상치료용 미더덕껍질 셀룰로오스필름의 제조 및 특성 분석

Preparation and Characterization of High Absorptive Cellulose Film Derived from Styela Clava Tunic for Wound Dressing

정영진|고은경|이승현|황대연|손홍주|이희섭|성금용|곽문화
한국염색가공학회 (The Korean Society Of Dyers And Finishers)|2015.03|한국염색가공학회지 (Textile Coloration and Finishing)|제27권 제1호|pp. 70-79

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참고문헌

키워드

absorptionStyela clava tuniccellulose filmfreeze-dryingwound dressing

초록

To establish the optimal conditions for the manufacture of high absortive cellulose film(CF) originated fromStyela clava tunic(SCT), the physicochemical properties included absorption was measured in CFs prepared under the variousconditions. The highest absorption was observed for SCT-CF20 prepared from the cellulose solution dissolved at 80°C for20 min, although the filtration treatment did not induce any significance alteration. Also, the absorption was higher inSCT-CF20-F prepared by the freeze drying than SCT-CF20-N (ambient air drying) and SCT-CF20-H (heat drying). Theaddition of porogen (NaHCO3) induced an increase of absorption in SCT-CF20-PF relative to SCT-CF20-F, while thenumber of interconnected porous structures was enhanced in SCT-CF20-PF. Furthermore, a high level of SK-MEL-2 cellsviability was observed in SCT-CF20-PN and SCT-CF20-PF cultured group. These results show that SCT-CF may havehigh absorption and biocompatibility when prepared from SCT cellulose solution dissolved at 80°C for 20 min after additionof porogen and then subjected to freeze drying.

Abstract

To establish the optimal conditions for the manufacture of high absortive cellulose film(CF) originated fromStyela clava tunic(SCT), the physicochemical properties included absorption was measured in CFs prepared under the variousconditions. The highest absorption was observed for SCT-CF20 prepared from the cellulose solution dissolved at 80°C for20 min, although the filtration treatment did not induce any significance alteration. Also, the absorption was higher inSCT-CF20-F prepared by the freeze drying than SCT-CF20-N (ambient air drying) and SCT-CF20-H (heat drying). Theaddition of porogen (NaHCO3) induced an increase of absorption in SCT-CF20-PF relative to SCT-CF20-F, while thenumber of interconnected porous structures was enhanced in SCT-CF20-PF. Furthermore, a high level of SK-MEL-2 cellsviability was observed in SCT-CF20-PN and SCT-CF20-PF cultured group. These results show that SCT-CF may havehigh absorption and biocompatibility when prepared from SCT cellulose solution dissolved at 80°C for 20 min after additionof porogen and then subjected to freeze drying.

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