Effect of Extraction Time on the Rheological Properties of Sericin Solutions and Gels
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초록
Recently, silk sericin has attracted the attention of researchers owing to its useful properties as a biomaterial including 1) good wound healing and cell activities, 2) fast gelation character,and 3) high water retention property. In the present study, silk sericin was prepared using different extraction times in hot water and the effect of extraction time on the rheological properties of sericin solutions and gels was examined. It was found that the production yield of sericin increased with extraction time. The shear viscosity of sericin solutions and gels decreased with increasing extraction time due to a decrease in sericin molecular weight. When the sericin solution transformed to a gel, the viscosity increased and the shear thinning behavior was more evident. In addition, the shear stress measurements indicated that the slip between the sericin samples and the measuring plate of the rheometer was increased by the gelation of sericin. The compression strength of sericin gel could be increased remarkably (by more than 100 fold) by preparation using the freezing and thawing method.
Abstract
Recently, silk sericin has attracted the attention of researchers owing to its useful properties as a biomaterial including 1) good wound healing and cell activities, 2) fast gelation character,and 3) high water retention property. In the present study, silk sericin was prepared using different extraction times in hot water and the effect of extraction time on the rheological properties of sericin solutions and gels was examined. It was found that the production yield of sericin increased with extraction time. The shear viscosity of sericin solutions and gels decreased with increasing extraction time due to a decrease in sericin molecular weight. When the sericin solution transformed to a gel, the viscosity increased and the shear thinning behavior was more evident. In addition, the shear stress measurements indicated that the slip between the sericin samples and the measuring plate of the rheometer was increased by the gelation of sericin. The compression strength of sericin gel could be increased remarkably (by more than 100 fold) by preparation using the freezing and thawing method.
참고문헌 (11)
- Cho HJ, "Effect of molecular weight and storage time on the wet- and electro-spinning of regenerated silk fibroin", Polym Degrad Stab, 97, pp.1060~1066 (2012)
- 조윤남, "The Effect of Extraction Conditions and Film Side on the Molecular Conformation of Silk Sericin Film", International Journal of Industrial Entomology, 26(2), pp.113~118 (2013), 한국잠사학회
- Ko JS, "Effect of degumming condition on the solution properties and electrospinnablity of regenerated silk solution", Int J Biol Macromol, 55, pp.161~168 (2013)
- Limpeanchob N, "Sericin reduces serum cholesterol in rats and cholesterol uptake into caco-2 cells", J Agric Food Che, 58, pp.12519~12522 (2010)
- Nagai N, "Enhancing effects of sericin on corneal wound healing in Otsuka long-evans Tokushima fatty rats as a model of human type 2 Diabetes", Biol Pharm Bull, 32, pp.1594~1599 (2009)
- HanJin Oh, "Enhanced Mechanical Property of Silk Sericin Beads Prepared fromEthanol-precipitated Sericin", International Journal of Industrial Entomology, 15(2), pp.171~174 (2007), 한국잠사학회
- Oh HJ, "Refining hot-water extracted silk sericin by ethanol-induced precipitation", Int J Biol Macromol, 28, pp.32~37 (2011)
- Seo C-W, "Antihyperlipidemic and Body Fat-Lowering Effects of Silk Proteins with Different Fibroin", Sericin Compositions in Mice Fed with High Fat Diet, 2011, pp.59, 4192~4197
- Tsubouchi K, "Sericin enhances attachment of cultured human skin fibroblasts", Biosci Biotechnol Biochem, 69, pp.403~405 (2005)
- Young Jin Yoo, "Examination of thermo-gelation behavior of HPMC and HEMC aqueous solutions using rheology", The Korea-Australia Rheology Journal, 25(2), pp.67~75 (2013), 한국유변학회
- Yun H, "Extraction conditions of Antherea mylitta sericin with high yields and minimum molecular weight degradation", Int J Biol Macromol, 52, pp.59~65 (2013)