Storage stability of silk solution for viscosity and electrospinnability
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In the present study, silk fibroin (SF) was dissolved in CaCl2/H2O/EtOH solution at 85℃. After the dissolution, the SF solution was cooled down and stored at 4℃ for 28 d. The stability of the solution`s viscosity and electrospinnability was observed to examine the stability of SF molecules during storage in CaCl2/H2O/EtOH solution. The viscosities of SF/CaCl2/H2O/ EtOH solution and SF formic acid solution did not change during 28 days` storage of SF in CaCl2/H2O/EtOH solution. The electrospinnability of the SF solution, mean diameter of the electrospun SF fiber, and crystallinity index of electrospun SF web did not change, regardless of the length of the storage period. These results imply that SF molecules do not degrade during 28 days` storage in CaCl2/H2O/EtOH solution.
Abstract
In the present study, silk fibroin (SF) was dissolved in CaCl2/H2O/EtOH solution at 85℃. After the dissolution, the SF solution was cooled down and stored at 4℃ for 28 d. The stability of the solution`s viscosity and electrospinnability was observed to examine the stability of SF molecules during storage in CaCl2/H2O/EtOH solution. The viscosities of SF/CaCl2/H2O/ EtOH solution and SF formic acid solution did not change during 28 days` storage of SF in CaCl2/H2O/EtOH solution. The electrospinnability of the SF solution, mean diameter of the electrospun SF fiber, and crystallinity index of electrospun SF web did not change, regardless of the length of the storage period. These results imply that SF molecules do not degrade during 28 days` storage in CaCl2/H2O/EtOH solution.
참고문헌 (21)
- Hee Jung Cho, "The Effect of Dissolution Condition on the Yield, Molecular Weight, and Wet- and Electro-spinnability of Regenerated Silk Fibroins Prepared by LiBr Aqueous Solution", International Journal of Industrial Entomology, 20(2), pp.99~105 (2010), 한국잠사학회
- Hee Jung Cho, "The Effect of Molecular Weight on the Gelation Behavior of Regenerated Silk Solutions", International Journal of Industrial Entomology, 23(1), pp.183~186 (2011), 한국잠사학회
- Cho HJ, "Effect of molecular weight and storage time on the wet- and electro-spinning of regenerated silk fibroin", Polym Degrad Stabil, 97, pp.1060~1066 (2012)
- Chung DE, "Effects of different Bombyx mori silkworm varieties on the structural characteristics and properties of silk", Int J Biol Macromol, 79, pp.943~951 (2015)
- Chung DE, "Effect of molecular weight and concentration on crystallinity and post drawing of wet spun silk fibroin fiber", Fiber Polym, 15, pp.153~160 (2014)
- Hirabayashi K, "Gelation of silk fibroin", Sen-I Gakkaish, 46, pp.521~524 (1990)
- Kim HJ, "Effect of degumming ratio on wet spinning and post drawing performance of regenerated silk", Int J Biol Macromol, 67, pp.387~393 (2014)
- Kim J, "Comparison of methods for the repair of acute tympanic membrane perforations: Silk patch vs. paper patch", Wound Rep Reg, 18, pp.132~138 (2010)
- Ko JS, "Effect of degumming condition on the solution properties and electrospinnablity of regenerated silk solution", Int J Biol Macromol, 55, pp.161~168 (2013)
- Kweon HY, "Development of Nano-Hydroxyapatite Graft With Silk Fibroin Scaffold as a New Bone Substitute", J Oral Maxillofac Surg, 69, pp.1578~1586 (2011)
- Lee JH, "Effect of residual sericin on the structural characteristics and properties of regenerated silk films", Int J Biol Macromol, 89, pp.273~278 (2016)
- 이우영, "Effectiveness of Woven Silk Dressing Materials on Full-skin Thickness Burn Wounds in Rat Model", Maxillofacial Plastic Reconstructive Surgery, 36(6), pp.280~284 (2014), 대한악안면성형재건외과학회[DOI]
- Minoura N, "Attachment and growth of cultured fibroblast cells on silk protein matrices", J Biomed Mater Res, 29, pp.1215~1221 (1995)
- Park BK, "Effect of MW, concentration and electric field on electrospinnability and electrospun web characters of regenerated silk", Master, pp.2016
- Park BK, "Effect of Korean Bombyx mori variety on electro-spinning performance of regenerated silk fibroin", Fiber Polym, 16, pp.1935~1940 (2015)
- Sakabe H, "In vivo blood compatibility of regenerated silk fibroin", Sen’i Gakkaishi, 45, pp.487~490 (1989)
- Song JY, "Accelerated healing with the use of a silk fibroin membrane for the guided bone regeneration technique", Oral Surg Oral Med Oral Pathol Oral Radiol Endod, 112, pp.e26~e33 (2011)
- Um IC, "Wet spinning of silk polymer: II. Effect of drawing on the structural characteristics and properties of filament", Int J Biol Macromol, 34, pp.107~119 (2004)
- InChulUm, "Structural Characteristics and Properties of Silk Fibroin", Polyurethane Blend Films, 2002, pp.5(2), 163~170[DOI]
- Um IC, "Structural characteristics and properties of the regenerated silk fibroin prepared from formic acid", Int J Biol Macromol, 29, pp.91~97 (2001)
- Yoon K, "Effects of degumming conditions on electro-spinning rate of regenerated silk", Int J Biol Macromol, 61, pp.50~57 (2013)