한국 정상 소아의 폐기능검사 추정 정상치
Predicted normal values of pulmonary function tests in normal Korean children
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초록
Purpose: Pulmonary function tests are useful and important methods for evaluating patients with respiratory diseases. To assess lung function, we need to establish normal values of lung function, which vary according to population, age, gender and growth, particularly in children. This study was undertaken to establish normal predicted values of pulmonary function tests and to predict renewed reference values by spirometry in Korean school children. Methods: Spirometric forced vital capacity (FVC), forced expiratory volume in 1 second (FEV1), forced expiratory flow at 25% to 75% of FVC (FEF25%-75%), and peak expiratory flow rate (PEFR) were measured in 406 healthy elementary school children (age, 6–12 years old) in May, 2012. Multiple linear regression analysis was performed for each spirometric parameter against age, height, weight and body surface area (BSA) separately for boys and girls, and derived reference equations and coefficients for all the spirometric parameters. Results: All the measured spirometric parameters were significantly correlated with age, height, weight, and BSA. FVC was higher in boys aged 6–10 years than girls at ages matched. Height showed the highest correlation coefficient for all the spirometric parameters followed by BSA, weight and age in both genders. The normal predicted values of FVC and FEV1 at 130 cm in this study using renewed reference equations were approximately in the middle compared to previous studies. Conclusion: We reported here the renewed reference equations for normal predicted values of pulmonary function tests with high coefficients of determination based on updated data in healthy Korean children.
Abstract
Purpose: Pulmonary function tests are useful and important methods for evaluating patients with respiratory diseases. To assess lung function, we need to establish normal values of lung function, which vary according to population, age, gender and growth, particularly in children. This study was undertaken to establish normal predicted values of pulmonary function tests and to predict renewed reference values by spirometry in Korean school children. Methods: Spirometric forced vital capacity (FVC), forced expiratory volume in 1 second (FEV1), forced expiratory flow at 25% to 75% of FVC (FEF25%-75%), and peak expiratory flow rate (PEFR) were measured in 406 healthy elementary school children (age, 6–12 years old) in May, 2012. Multiple linear regression analysis was performed for each spirometric parameter against age, height, weight and body surface area (BSA) separately for boys and girls, and derived reference equations and coefficients for all the spirometric parameters. Results: All the measured spirometric parameters were significantly correlated with age, height, weight, and BSA. FVC was higher in boys aged 6–10 years than girls at ages matched. Height showed the highest correlation coefficient for all the spirometric parameters followed by BSA, weight and age in both genders. The normal predicted values of FVC and FEV1 at 130 cm in this study using renewed reference equations were approximately in the middle compared to previous studies. Conclusion: We reported here the renewed reference equations for normal predicted values of pulmonary function tests with high coefficients of determination based on updated data in healthy Korean children.
참고문헌 (31)
- Ruppel GL, "Pulmonary function testing", Respir Care, 57, pp.165~175 (2012)
- Beydon N, "An official American Thoracic Society", European Respiratory Society statement: pulmonary function testing in preschool children, 2007, pp.175, 1304~1345
- Lim DH, "Normal predicted values of pulmonary function test in Korean primary school-aged children", J Korean Pediatr Soc, 37, pp.240~249 (1994)
- Yoon KA, "Normal predicted values of pulmonary function test in Korean school-aged children", J Korean Pediatr Soc, 36, pp.25~37 (1993)
- Cha IA, "Normal predicted vlues of pulmonary function test in children", J Korean Pediatr Soc, 37, pp.672~688 (1994)
- Nam SY, "Normal predicted values of pulmonary function test in healthy Korean children", J Korean Pediatr Soc, 41, pp.338~345 (1998)
- Cho A, "Expected normal values of pulmonary function test in normal children (ages 6 years through 12 years)", Allergy, 12, pp.517~527 (1992)
- Yoon JS, "A study of predicted values of peak expiratory flow rates in primary school children", J Korean Pediatr Soc, 34, pp.487~496 (1991)
- Yang SY, "Expected normal values of pulmonary function test in pediatric age 1. by spirometry", J Korean Pediatr Soc, 32, pp.206~214 (1989)
- Lim SY, "A study on predicted values of peak expiratory flow rate (PEER) in primary school children", J Korean Pediatr Soc, 29, pp.1104~1113 (1986)
- Ip MS, "Lung function reference values in Chinese children and adolescents in Hong Kong. I. Spirometric values and comparison with other populations", Am J Respir Crit Care Med, 162(2 Pt 1), pp.424~429 (2000)
- Nystad W, "Feasibility of measuring lung function in preschool children", Thorax, 57, pp.1021~1027 (2002)
- Torres LA, "Correlation between standing height, sitting height, and arm span as an index of pulmonary function in 6-10-year-old children", Pediatr Pulmonol, 36, pp.202~208 (2003)
- Al-Riyami BM, "Normal spirometric reference values for Omani children and adolescents", Respirology, 9, pp.387~391 (2004)
- Jeng MJ, "Spirometric pulmonary function parameters of healthy Chinese children aged 3-6 years in Taiwan", Pediatr Pulmonol, 44, pp.676~682 (2009)
- 2007 Korean Children and Adolescents Growth Standard(commentary for the development of 2007 growth chart), "Korea Centers for Disease Control and Prevention", Korea Centers for Disease Control and Prevention, Division of Chronic Disease Surveillance, ~ (2007)
- Gehan EA, "Estimation of human body surface area from height and weight", Cancer Chemother Rep, 54, pp.225~235 (1970)
- Primhak RA, "Factors affecting the peak expiratory flow rate in children", Br J Dis Chest, 78, pp.26~35 (1984)
- Morse M, "The lung volume and its subdivisions in normal boys 10-17 years of age", J Clin Invest, 31, pp.380~391 (1952)
- Knudson RJ, "Changes in the normal maximal expiratory flow-volume curve with growth and aging", Am Rev Respir Dis, 127, pp.725~734 (1983)
- Thurlbeck WM, "Postnatal human lung growth", Thorax, 37, pp.564~571 (1982)
- Crapo RO, "Reference spirometric values using techniques and equipment that meet ATS recommendations", Am Rev Respir Dis, 123, pp.659~664 (1981)
- Schoenberg JB, "Growth and decay of pulmonary function in healthy blacks and whites", Respir Physiol, 33, pp.367~393 (1978)
- Peabody FW, "Clinical studies of the respiration. IV. The vital capacity of the lungs and its relation to dyspnea", Arch Int Med, 20, pp.443~467 (1917)
- Lundsgaard C, "Studies of lung volume. I: relation between thorax size and lung volume in normal adults", J Exp Med, 27, pp.65~86 (1918)
- Dockery DW, "Distribution of forced vital capacity and forced expiratory volume in one second in children 6 to 11 years of age", Am Rev Respir Dis, 128, pp.405~412 (1983)
- Leeder SR, "Maximum expiratory flow-volume curves in children: changes with growth and individual variability", Bull Eur Physiopathol Respir, 13, pp.249~260 (1977)
- Taussig LM, "Different mechanical properties of the lung in boys and girls", Am Rev Respir Dis, 123, pp.640~643 (1981)
- Taussig LM, "Maximal expiratory flows at functional residual capacity: a test of lung function for young children", Am Rev Respir Dis, 116, pp.1031~1038 (1977)
- Zapletal A, "Pulmonary function studies in children living in an air-polluted area", Am Rev Respir Dis, 107, pp.400~409 (1973)
- Tager IB, "Longitudinal study of the effects of maternal smoking on pulmonary function in children", N Engl J Med, 309, pp.699~703 (1983)