알코올 금단 섬망 발생의 예측
Prediction of the Development of Alcohol Withdrawal Delirium
0
조회
0
다운로드
2
인용
0
참고문헌
키워드
초록
Abstract
Objectives：Alcohol withdrawal delirium is a serious clinical condition with high mortality rate if not treated. This study was to examine whether readily available clinical variables can predict the development of alcohol withdrawal delirium. Methods：The authors performed a retrospective study by reviewing charts of 566 patients who had been admitted for alcohol dependence. The cases were divided into two groups: delirium group (n=40) and control group (n=40). We compared baseline characteristics and serum analysis data at admission between two groups. We used logistic regression to predict risk factors for alcohol withdrawal delirium among potential risk factors. Results：The delirium group had significantly lower hemoglobin, hematocrit, platelet counts, and potassium level than countrol group. Presence of previous withdrawal delirium history, AST, GGTP, and bilirubin level of delirium group were significantly higher than those of control group. Among potential risk factors, past history of withdrawal delirium, decreased hemoglobin, elevated bilirubin level, and number of previous detoxification were predictable factors of the development of alcohol withdrawal delirium by 72.5%. Conclusion：Our results suggest that the infomation obtained at admission can be useful to predict the development of alcohol withdrawal delirium. Also, it makes the individualization of detoxification strategies possible. (J Korean Neuropsychiatr Assoc 2004;43(5):559-563)
참고문헌 (21)
- "Pharmacological management of alcohol withdrawal:A meta-analysis and evidence-based practice guideline", 278, pp.144~151 (1997)
- "Synopsis of psychiatry: behavioralscience", clinical psychiatry, 2003, 403~406
- "Substance use disorders", pp.317~ (2003), The American Psychiatric Press
- "Clinical Predictorsof Alcohol Withdrawal Delirium", 18, pp.1100~1102 (1994)
- "Thehistories of withdrawal convulsions and delirium tremens in 1648alcohol dependent subjects", 90, pp.1335~1347 (1995)
- "Risk factorsfor delirium tremens development", 11, pp.410~414 (1996)
- "Delirium tremens:update on an old disorder", 82, pp.117~122 (1987)
- "Diagnostic and StatisticalManual of Mental Disorders" (1994)
- "Alcohol detoxificationand withdrawal seizures:clinical support for a kindling hypothesis", 23, pp.507~514 (1988)
- "Seizure risk with recurrent alcohol detoxification", 47, pp.535~538 (1990)
- "Relative kindling effect of detoxificationand non-detoxification admissions in alcoholics", 26, pp.221~225
- "Risk for deliriumtremens in patients with alcohol withdrawal syndrome", 23, pp.83~94 (2002)
- "Kindling as a model for alcohol withdrawalsyndromes", 133, pp.1~14 (1978)
- "Alcoholic withdrawalsyndrome and seizures", 29, pp.323~328 (1994)
- "Persistent delirium following cessationof heavy alcohol consumption:diagnostic and treatment implications", 154, pp.846~851 (1997)
- "Assessment of the role of kindlingin the pathogenesis of alcohol withdrawal seizures and deliriumtremens", 23, pp.204~208 (1999)
- "Pathogenesis,diagnosis,and treatmentof alcoholic liver disease", 76, pp.1021~1029 (2001)
- "Delirium tremens in Copenhagen", 187, pp.1~92
- "Haematological changes and state of hydrationduring delirium tremens and related clinical states", 62, pp.511~518 (1980)
- "The hematologic complications of alcoholism", 21, pp.42~52 (1997)
- "Does hypokalemia precede delirium tremens", 8089, pp.549~550 (1978)