소아에서 성공한 isoniazid와 rifampin에 대한 신속탈감작요법 1예
Rapid desensitization to isoniazid and rifampin in an adolescent with active pulmonary tuberculosis
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초록
Hypersensitivity reactions to antituberculosis medicine are obstacles to the treatment of tuberculosis. However, rapid drug desensi- tization can secure successful treatment with essential antituberculosis medicines in pediatric patients. A 17-year-old boy with ac- tive pulmonary tuberculosis complained of generalized erythematous rashes, pruritus on the 11th day of tuberculosis treatment. He was diagnosed with hypersensitivity reactions to isoniazid and rifampin by the oral provocation test. After desensitization, the patient continued to take antituberculosis treatment with isoniazid, rifampin, pyrazinamide, and ethambutol. We report here a case of successful desensitization in an adolescent with hypersensitivity to isoniazid and rifampin.
Abstract
Hypersensitivity reactions to antituberculosis medicine are obstacles to the treatment of tuberculosis. However, rapid drug desensi- tization can secure successful treatment with essential antituberculosis medicines in pediatric patients. A 17-year-old boy with ac- tive pulmonary tuberculosis complained of generalized erythematous rashes, pruritus on the 11th day of tuberculosis treatment. He was diagnosed with hypersensitivity reactions to isoniazid and rifampin by the oral provocation test. After desensitization, the patient continued to take antituberculosis treatment with isoniazid, rifampin, pyrazinamide, and ethambutol. We report here a case of successful desensitization in an adolescent with hypersensitivity to isoniazid and rifampin.
참고문헌 (17)
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