본문 바로가기
KERD
논문

한국의 소아 천식의 연구 현황과 과제

Studies and proposals of childhood asthma in Korea

1

조회

0

다운로드

6

인용

0

참고문헌

키워드

주제분류소아과학

초록

This review mainly focuses on the academy and research group published on childhood asthma and aims to investigate the impact of Korean study results in this field. The International Study of Asthma and Allergies in Childhood (ISAAC) questionnaires have shown that the prevalence of childhood asthma is increasing worldwide. The ISAAC, which Korea joined in 1995, has enabled us to compare prevalence between countries. Korea has participated in three ISAAC surveys: 3 nationwide surveys in 1995, 2000, and 2010. The 12-month prevalence of asthma symptoms from the questionnaires was 4.9%–10.1% for children aged 6–7 years. In Korea, ISAAC surveys demonstrated that risk factors for asthma are obesity, secondhand smoking, diet patterns, raising pets, fever in infancy, and the use of antibiotics. However, because these were large-scale but cross-sectional studies, prospective cohort studies on growth patterns from prenatal through postnatal periods are needed to elucidate accurate risk factors. In 2016, 2 research groups were united to Korea childhood Asthma RESearch (KARES). Several studies were published from KARES. We reported prevalence of each asthma severity category and the controller prescription patterns according to asthma severity assessed by a Western (Global Initiative for Asthma) and an Asia-Pacific (Japanese Pediatric GuideLine) guideline were evaluated. And we translate the Test for Respiratory and Asthma Control in Kids instrument into Korean, with subsequent linguistic validation. The role of the Korean Academy of Pediatric Allergy and Respiratory Disease will be important for the prevent the child and adolescent asthma through the various Korean child data made.

Abstract

This review mainly focuses on the academy and research group published on childhood asthma and aims to investigate the impact of Korean study results in this field. The International Study of Asthma and Allergies in Childhood (ISAAC) questionnaires have shown that the prevalence of childhood asthma is increasing worldwide. The ISAAC, which Korea joined in 1995, has enabled us to compare prevalence between countries. Korea has participated in three ISAAC surveys: 3 nationwide surveys in 1995, 2000, and 2010. The 12-month prevalence of asthma symptoms from the questionnaires was 4.9%–10.1% for children aged 6–7 years. In Korea, ISAAC surveys demonstrated that risk factors for asthma are obesity, secondhand smoking, diet patterns, raising pets, fever in infancy, and the use of antibiotics. However, because these were large-scale but cross-sectional studies, prospective cohort studies on growth patterns from prenatal through postnatal periods are needed to elucidate accurate risk factors. In 2016, 2 research groups were united to Korea childhood Asthma RESearch (KARES). Several studies were published from KARES. We reported prevalence of each asthma severity category and the controller prescription patterns according to asthma severity assessed by a Western (Global Initiative for Asthma) and an Asia-Pacific (Japanese Pediatric GuideLine) guideline were evaluated. And we translate the Test for Respiratory and Asthma Control in Kids instrument into Korean, with subsequent linguistic validation. The role of the Korean Academy of Pediatric Allergy and Respiratory Disease will be important for the prevent the child and adolescent asthma through the various Korean child data made.

참고문헌 (36)

  1. Asher MI, "International Study of Asthma and Allergies in Childhood (ISAAC): rationale and methods", Eur Respir J, 8, pp.483~491 (1995)[DOI]
  2. Asher MI, "Worldwide time trends in the prevalence of symptoms of asthma, allergic rhinoconjunctivitis, and eczema in childhood: ISAAC Phases One and Three repeat multicountry cross-sectional surveys", Lancet, 368, pp.733~743 (2006)[DOI]
  3. Hong SJ, "Self-reported prevalence and risk factors of asthma among Korean adolescents: 5- year follow-up study, 1995-2000", Clin Exp Allergy, 34, pp.1556~1562 (2004)[DOI]
  4. 안강모, "2010년 한국 어린이·청소년의 천식, 알레르기 비결막염, 아토피피부염 증상 유병률 조사: 복합표본설계를 이용한 전국 서베이", 대한의사협회지, 54(7), pp.769~778 (2011), 대한의사협회
  5. Lee SI, "Prevalences of symptoms of asthma and other allergic diseases in korean children: a nationwide questionnaire survey", J Korean Med Sci, 16, pp.155~164 (2001)[DOI]
  6. Cha JK, "Development and multicenter study on Korean pediatric asthma caregiver's quality of life questionnaire (KPACQLQ)", J Asthma Allergy Clin Immunol, 20, pp.480~491 (2000)
  7. 김미숙, "초등학생 기도과민성의 유병률과 연관 인자", Allergy Asthma & Respiratory Disease, 2(3), pp.171~178 (2014), 대한 소아알레르기 호흡기학회
  8. Kim YY, "Prevalence of childhood asthma based on questionnaires and methacholine bronchial provocation test in Korea", Clin Exp Allergy, 27, pp.761~768 (1997)[DOI]
  9. 권지원, "Changes in the Prevalence of Childhood Asthma in Seoul from 1995 to 2008 and Its Risk Factors", Allergy, Asthma & Immunology Research, 3(1), pp.27~33 (2011), 대한천식알레르기학회
  10. 이연희, "한국 어린이 청소년의 알레르기질환에 관한 지역별 유병률에 대한 분석", Allergy Asthma & Respiratory Disease, 3(1), pp.62~69 (2015), 대한 소아알레르기 호흡기학회
  11. 박종진, "학동기 천식에서 성인 초기까지 천식의 지속에 미치는인자들 : 폐기능 및 기관지 과민성을 중심으로", Allergy Asthma & Respiratory Disease, 18(2), pp.29~38 (2008), 대한 소아알레르기 호흡기학회
  12. Lai CK, "Global variation in the prevalence and severity of asthma symptoms: phase three of the International Study of Asthma and Allergies in Childhood (ISAAC)", Thorax, 64, pp.476~483 (2009)[DOI]
  13. Investigation of the reference ranges of respiratory and allergic diseases test based on disease diagnosis in nationwide randomized general pediatric population, "Korea Centers for Disease Control and Prevention", Korea Centers for Disease Control and Prevention, ~ (2015)
  14. Standardization study or the diagnosis and treatment of pediatric allergic diseases, "Korea Centers for Disease Control and Prevention", Korea Centers for Disease Control and Prevention, ~ (2010)
  15. Clifford RD, "Symptoms, atopy, and bronchial response to methacholine in parents with asthma and their children", Arch Dis Child, 62, pp.66~73 (1987)[DOI]
  16. Townley RG, "Segregation analysis of bronchial response to methacholine inhalation challenge in families with and without asthma", J Allergy Clin Immunol, 77(1 Pt 1), pp.101~107 (1986)[DOI]
  17. Hopp RJ, "Methacholine inhalation challenge studies in a selected pediatric population", Am Rev Respir Dis, 134, pp.994~998 (1986)[DOI]
  18. Hopp RJ, "Genetic analysis of allergic disease in twins", J Allergy Clin Immunol, 73, pp.265~270 (1984)[DOI]
  19. Kim YK, "Skin reactivity to inhalant allergens, total serum IgE levels, and bronchial responsiveness to methacholine are increased in parents of nonatopic asthmatic children", J Allergy Clin Immunol, 104(2 Pt 1), pp.311~316 (1999)[DOI]
  20. Johnston SL, "Natural and experimental rhinovirus infections of the lower respiratory tract", Am J Respir Crit Care Med, 152(4 Pt 2), pp.S46~S52 (1995)[DOI]
  21. Rakes GP, "Rhinovirus and respiratory syncytial virus in wheezing children requiring emergency care. IgE and eosinophil analyses", Am J Respir Crit Care Med, 159, pp.785~790 (1999)[DOI]
  22. Olenec JP, "Weekly monitoring of children with asthma for infections and illness during common cold seasons", J Allergy Clin Immunol, 125, pp.1001~1006 (2010)[DOI]
  23. Corne JM, "The relationship between atopic status and IL-10 nasal lavage levels in the acute and persistent inflammatory response to upper respiratory tract infection", Am J Respir Crit Care Med, 163, pp.1101~1107 (2001)[DOI]
  24. Johnston NW, "Asthma exacerbations. 1: epidemiology", Thorax, 61, pp.722~728 (2006)[DOI]
  25. Wark PA, "Asthmatic bronchial epithelial cells have a deficient innate immune response to infection with rhinovirus", J Exp Med, 201, pp.937~947 (2005)[DOI]
  26. Wood LG, "Induced sputum 8-isoprostane concentrations in inflammatory airway diseases", Am J Respir Crit Care Med, 171, pp.426~430 (2005)[DOI]
  27. Veitenhansl M, "40th EASD Annual Meeting of the European Association for the Study of Diabetes : Munich, Germany, 5-9 September 2004", Diabetologia, 47(Suppl 1), pp.A1~A464 (2004)[DOI]
  28. Green RM, "Synergism between allergens and viruses and risk of hospital admission with asthma: case-control study", BMJ, 324, pp.763~ (2002)
  29. Kondo S, "Progressive bronchial obstruction during the acute stage of respiratory tract infection in asthmatic children", Chest, 106, pp.100~104 (1994)[DOI]
  30. Chang YT, "The significance of a rapid cold hemagglutination test for detecting mycoplasma infections in children with asthma exacerbation", J Microbiol Immunol Infect, 39, pp.28~32 (2006)
  31. Yamashita R, "Eosinophil cationic protein in the sera of patients with Mycoplasma pneumonia", Pediatr Infect Dis J, 13, pp.379~381 (1994)[DOI]
  32. Kondo N, "Japanese pediatric guidelines for the treatment and management of bronchial asthma 2008", Pediatr Int, 52, pp.319~326 (2010)[DOI]
  33. [URL]
  34. 서동인, "Asthma Severity and the Controller Prescription in Children at 12 Tertiary Hospitals", Allergy, Asthma & Immunology Research, 9(1), pp.52~60 (2017), 대한천식알레르기학회
  35. 오혜린, "Test for Respiratory and Asthma Control in Kids 설문지의 한국어 번역 및 번역본의 언어 타당도", Allergy Asthma & Respiratory Disease, 4(1), pp.22~30 (2016), 대한 소아알레르기 호흡기학회[DOI]
  36. 서민아, "Prevalence of Allergic Diseases among Korean School-age Children: A Nationwide Cross-Sectional Questionnaire Study", Journal of Korean Medical Science, 26(3), pp.332~338 (2011), 대한의학회

관련 논문AI추천