돼지고기에 감작된 환아에서 발생한 돼지고기 의존성 운동 유발성 아나필락시스 1례
A Case Report of Food-Dependent Exercise-Induced Anaphylaxis in a Patient who was Sensitive to Pork
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초록
식품 의존성 운동 유발성 아나필락시스는 물리적 운동과 특정 음식물에 의해 아나필락시스가 유발된다. 저자는 돼지고기 섭취 후 격렬한 운동 뒤에 아나필락시스가 유발된 15세 여아에서, 알레르기 피부시험, 식품유발시험 및 운동유발시험으로 확진된 돼지고기 의존성 운동 유발성 아나필락시스를 경험하였기에 보고하는 바이다.
Abstract
Food-dependent exercise-induced anaphylaxis (FDEIA) is a specific variant of exercise-induced anaphylaxis that requires both vigorous physical activity and the ingestion of specific foods. In particular, it is rare occurrence for FDEIA to be associated with meat in Korea. A 15-year-old female had generalized urticaria, dyspnea, severe cough, headache, dizziness, and vomiting after singing and dancing for 1 hour and after ingesting grilled pork. Skin prick tests showed a strong positive reaction to pork, whereas the results of an oral food challenge and exercise provocation tests were negative. However, the exercise provocation test after pork ingestion showed a positive reaction manifested by generalized urticaria, cough, mild dyspnea, and a 23% decreased peak expiratory flow rate. Three allergens to pork (67 kDa, 90 kDa, and 15 kDa) reacted with the patient’s serum on immunoglobulin E immunoblotting. We report a case of pork-dependent exercise-induced anaphylaxis in a patient who was sensitive to pork.
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