(Review) Solid-state NMR Study on Membrane Protein Structure in Biological Condition
2
조회
0
다운로드
0
인용
0
참고문헌
키워드
초록
Membrane proteins play a essential role in the biological systems and it is not easy to handle a membrane protein for its structural study. Solid-state NMR (ssNMR) can be a good tool to investigate the structures and dynamics of membrane proteins. In ssNMR, Magic Angle Spinning (MAS) and Cross Polarization (CP) can be utilized to reduce the line-broadening, leading to high resolution and sensitivity in the spectrum. ssNMR, if combined with other spectroscopic methods, can provide us a enough knowledge on structures and dynamics of membrane proteins in biological condition.
Abstract
Membrane proteins play a essential role in the biological systems and it is not easy to handle a membrane protein for its structural study. Solid-state NMR (ssNMR) can be a good tool to investigate the structures and dynamics of membrane proteins. In ssNMR, Magic Angle Spinning (MAS) and Cross Polarization (CP) can be utilized to reduce the line-broadening, leading to high resolution and sensitivity in the spectrum. ssNMR, if combined with other spectroscopic methods, can provide us a enough knowledge on structures and dynamics of membrane proteins in biological condition.
참고문헌 (15)
- R. B. Russell, , Nat. Struct. Biol, 7, pp.928~ (2000)
- N. Nielsen, , Mol. Membr. Biol, 21, pp.129~ (2004)
- M. Auger, , Curr. Issues Mol. Biol, 2, pp.119~ (2000)
- S. Luca, , Acc. Chem. Res, 36, pp.858~ (2003)
- S. J. Opella, , Biochem. Cell. Biol, 80, pp.597~ (2002)
- S. J. Opella, "NMR Structural Studies of Membrane Proteins", Journal of the Korean Magnetic Resonance Society, 2(2), pp.120~130 (1998), 한국자기공명학회
- G. Wang, , Curr Protein Pept. Sci, 9, pp.50~ (2008)
- C. Glaubitz, , J. Magn. Reson, 130, pp.305~ (1998)
- 한덕영, "Solid-State High-Resolution ¹H-NMR Study for Ammonia Borane of Hydrogen Storage Material", Journal of the Korean Magnetic Resonance Society, 14(1), pp.38~44 (2010), 한국자기공명학회
- A. Drechsler, , IUBMB Life, 55, pp.515~ (2003)
- M. J. Duer, "Solid-State NMR Spectroscopy Principles and Applications", pp.i~xviii (2007), Blackwell Science Ltd
- S. Paasch, , Anal. Bioanal. Chem, 398, pp.2351~ (2010)
- M. Renault, , Angew. Chem. Int. Ed Engl, 49, pp.8346~ (2010)
- R. G. Griffin, , Nat. Struct. Biol, 5, pp.508~ (1998)
- "Introductory Solid State NMR Notes"[URL]